New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...o the primary deficits in muscle metabolisms which underlie the progression of obesity-related diseases," Hittel said. In conclusion Hittel said, "we propose that changes in glucose metabolism which occur in aerobic exercise trained skeletal muscle are also responsible for the cardiovascular benefits...Mitochondria findings may help beat wide range of disease
...studies analyzing the mechanisms and proteins that underlie the fission-fusion cycle of the cellular powerplan... "Understanding the discrete molecular events that underlie dynamic mitochondrial behavior has the potential to reveal keen insights into the basic and essentia...Highlights of American Anthropological Assoc. meeting
...ions and misconceptions of what is meant by "race" underlie most health research. This session asks "how are race and human variation related to health?" (10.15-Noon) Anthropology Beyond Bagdad: A Roundtable Discussion. (1.45-3.30 p.m.) The Anthropology of Crisis in the Middle East: Presenters discu...Using fruitflies to examine alcohol tolerance
...y their suggestion that different genetic pathways underlie these two forms of tolerance." Crabbe had specific suggestions for future research in this area. "The authors of this study distinguish between two types of alcohol tolerance, rapid and chronic," he said. "There is a third general type of toleranc...Identifying genes that contribute to a low level of response to alcohol
...ation, which directly implies there are genes that underlie that heritability. Step three, he added, is the current study that seeks to identify those genes. Schuckit and his colleagues reviewed both animal and human English-language studies developed since January 1998, listed on Medline, and with appropri......ity that mutations in BMP signaling components may underlie some of the genetic variation in human osteoarthritis risk and suggests that treatments designed to mimic or augment BMP signaling might help to maintain healthy joints....Gene for Joubert syndrom with excessive brain folds discovered by UCSD researchers and Harvard team
...that the genes causing this condition are going to underlie more common childhood brain and behavioral abnormalities, such as autism, mental retardation, and poor coordination" said the UCSD paper's senior author, Joseph Gleeson, M.D., assistant professor of neurosciences at UCSD and Children's Hospital San D...Researchers discover gene mutations for Parkinson's disease
...rtant new information about genetic mutations that underlie this disease, giving us new understanding about molecular mechanisms. Ultimately, this research will help in the development of targeted interventions that could actually alter the course of this disabling disease." The gene, PARK8, encodes a protein...Brain differences in adolescents, psychopaths, lend to their impulsive, risk-taking behavior
...f adolescent brains compared with adult brains may underlie adolescents' immature decision making. The researchers intermittently administered primary rewards of squirts of juice and water to adolescents aged 13 to 17 and to adults aged 30 to 50, while simultaneously viewing their brain activity with f...Yerkes researchers to present array of new data at Society for Neuroscience Meeting
... further understand the neurochemical changes that underlie addiction and drug abuse. (2 pm 3 pm) Dr. Young and his research team: examined the potential genetic mechanisms underlying individual differences in personality traits by demonstrating an association between vasopressin receptor gene structure ...Rethinking new therapies for Crohn's disease at U.Va.
...nal hypotheses about the biological processes that underlie Crohn's disease, according to Cominelli, a leading Crohn's expert. More than half a million people in the U.S. suffer from Crohn's,a chronic disease involving inflammation of the intestines. Cominelli indicates that more cytokines- proteins tha...Signal for inflammation linked to Ras-induced tumor growth
...rounding environment. However, the mechanisms that underlie these interactions are unclear. Dr. Dafna Bar-Sagi from the Department of Molecular Genetics and Microbiology at the State University of New York at Stony Brook examined whether Ras-mediated induction of the inflammatory mediator CXCL-8 was required...Genetic influences on taste perception of alcohol may influence alcohol intake
...ing alcohol. Whether the genetic differences that underlie sensitivity to bitter tastes contribute to early experimentation with alcohol is an important area for future research."...Children's Hospital Boston launches major genetic study of autism
... uncover other genes and biochemical pathways that underlie autism. Children and families enrolled in the Children's study also will be invited to take part in research at MIT's Department of Brain and Cognitive Sciences. Study participants will be tested for their ability to recognize and respond to faces ...Genetic defect confers risk of major depression, resistance to SSRI drug therapy
...uggesting that the human variant of the gene might underlie psychiatric disorders characterized by low levels ...or aberrations in the production of serotonin that underlie depression and other neuropsychiatric disorders." "We believe this is a major finding with implicat...Mutant gene linked to treatment-resistant depression
...rk via serotonin, suggesting that the mutation may underlie a treatment-resistant subtype of the illness. The mutant gene codes for the brain enzyme, tryptophan hydroxylase-2, that makes serotonin, and results in 80 percent less of the neurotransmitter. It was carried by nine of 87 depressed patients, thre...Fox Chase Cancer Center scientists discover key proteins linked to aging and cancer
... irreversible stage in a cell's life cycle and may underlie the human aging process and have an impact on diseases of aging, such as adult cancers. "Most importantly, the failure of cells to stop growing through differentiation or senescence can lead to the uncontrolled growth of cancer," Adams emphasized. B...Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2005
...depict the infinitesimally complex structures that underlie the functionality and delicate spectacle of the flying insect's wing. Using the instrument, researchers can see nanometer-sized structural elements at resolutions that roughly equal the size of a DNA molecule. ORNL researcher Sergei Kalinin says the ...Cleft palate research receives 200,000 award
...introduce a mutation in p63 that has been shown to underlie cleft palate using gene-targeting technology. This strategy will allow her to investigate the downstream effects of this mutation on other proteins involved in palatal development. In the short term, the results of this research will help to dissect ......rch in order to better understand the factors that underlie cancer....