Researchers extend mouse lifespan by protecting against free radicals
... we're realizing now is that by intervening in the underlying aging process, we may be able to produce very significant increases in 'healthspan,' or healthy lifespan."...Researchers map 'circuitry' of yeast genes using technique that could be applied to humans
...tic interactions in yeast are thought to mimic the underlying basis of human diseases in which combinations of mutated genes, rather than mutations of single genes, are at fault. Geneticists have traditionally studied yeast because it grows rapidly and each stage of its cell cycle is easy to visualize. Scientis...Employing ecology to predict and manage emerging infectious diseases
...tists that share questions of common interest." An underlying theme throughout the conference was the need to incorporate ecological methods into traditional epidemiological studies. Participant Dr. Andy Dobson, an ecologist at Princeton University, noted, "When trying to unravel the infectious diseases of plan...NIH funds DOE lab for cellular studies
...mbrane in order to provide an understanding of the underlying mechanisms. Researchers will also examine which factors are important in the resistance of P. aeruginosa for antibiotics designed to disrupt the outer membrane, giving insight into why P. aeruginosa is elusive to treatment. The structures of the out...Heart failure wall stress drops 38% with moderate thyroid hormone therapy
...important, Gerdes said, because no matter what the underlying cause of heart failure in humans, the last phase in heart failure progression to dilatation is always accompanied by elongation of heart muscle cells (myocytes), without concomitant cell widening. The paper notes that "it isn't clear at this time ...Clincal trials indicate NEXIUM can reduce upper GI symptoms in patients using NSAIDS
...ny patients because of the chronic nature of their underlying condition, said James M. Scheiman, M.D., Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan. These two trials demonstrate that NEXIUM was effective in reducing upper GI symptoms of patients on c...For young canaries learning their song, freedom in youth gives way to rules in adulthood
...would not normally do you can learn more about the underlying mechanisms." "The song of canaries is characterized by a successive repetition of sounds, each sound repeated many times forming a phrase," Nottebohm explains, "for example, AAAAA BBBBB CCCCC and so on, where each letter stands for a sound repeated ...Lipids get new comprehensive classification system
...dividual lipids and their derivatives. The concept underlying the new methodology is that head groups are drawn on the right side and the hydrocarbon chain extends to the left. In the simplest case of the fatty acid derivatives, the acid group is drawn on the right and the hydrophobic hydrocarbon chain is on th...Function of cancer genes discovered
...enetic screens to discover the molecular mechanism underlying cylindromatosis. Nijman's research revealed that the CYLD protein plays an important role in the NF-kappa B signalling route. This is a cellular communications system which becomes overactive if the CYLD protein is mutated. This results in increased ...Colleagues, friends gather to commemorate Nobel Laureate Axelrod
...he brain responds to stress; neural communications underlying appetite and addiction; and how individuals react differently to drugs depending on their genetic makeup. Overflow rooms for NIH staff will be available in Natcher Auditorium. The symposium can also be viewed online at http://videocast.nih.gov/ . F...To stop evolution: New way of fighting antibiotic resistance demonstrated by Scripps scientists
...se the mutations responsible for evolution are the underlying causes of cancer and aging as well. ...e force," says Romesberg. "There is a biochemistry underlying it and it is subject to intervention." The Scourge of Antibiotic Resistance One th...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...nced graduate course at Scripps--that analyzed the underlying dynamics responsible for major shifts in biological and physical conditions of the North Pacific Ocean over the 20th century. Scientists hoping to understand the behavior of the North Pacific have centered their analyses on "regime shifts," decades-l...Fibromyalgia patients may benefit from cough remedy, UF study finds
...ave problems related to memory and confusion." The underlying cause of fibromyalgia remains unknown, but in the past 25 years substantial progress has been made toward understanding the mechanisms behind specific features of fibromyalgia, Staud said. One is central sensitization, a feature of many chronic pain ...Lack of coherent cloning policies reflects polarized debate, limited understanding, study says
...ese divergent views in turn are based on different underlying values, including the view of the moral worth of a human embryo, conceptions of human personhood and human dignity, the importance of human individuality, the imperative to heal the sick, the right to reproductive autonomy, and the proper role of gov...The lopsided brain: Attention bias is shared by humans and birds
...ut past work has suggested that brain organization underlying attention asymmetries may offer benefits in spatial learning and in performing simultaneous spatial tasks, such as looking for food while being vigilant for predators....Protein prevents detrimental immune effects of bacterial sepsis
...ems. When such patients are unable to control the underlying bacterial infection, their immune systems overcompensate and trigger a dangerous cascade of tissue damage. Thus, to prevent death from sepsis, physicians must not only control the bacterial infection but better control the detrimental effects of th...Vampires beware: Scripps scientists describe molecular basis of raw garlic's pungency
...ed to Patapoutian's longstanding research into the underlying mechanisms of how we feel pain. Knowing that allicin activates TRPV1 and TRPA1 reveals important information about these receptors, which may help in the eventual design of compounds to modulate the activity of these channels. Indeed, several compoun...Study: 'homemade' gene expression technology unreliable
...orthwest National Laboratory focuses on mechanisms underlying Superfund chemicals with neurotoxic properties; the other with the OHSU School of Medicine's Department of Pediatrics focuses on neurotoxicogenomics and child health. Srinivasa Nagalla, M.D., associate professor of pediatrics, and cell and developmen...Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
...epression. Our study may also suggest some of the underlying physiology of stalking behavior," she added. Fisher noted that their study, which took barely an hour for each participant but many years for the researchers to process and interpret the data, also found a "fascinating continuity between human roman......d Lipowsky, will elucidate the molecular mechanism underlying this force generation and will explore new possibilities for the integration of these molecular machines into nano- and microsystems. The network was launched on May 1, 2005. Biomimetic systems mimic or imitate certain aspects of biological systems....