Dr. Harris receives NIH Javits Neuroscience Investigator Award
... synapses that likely will not only help us better understand how we learn and remember but also pave the way for better treatments of diseases that disrupt these processes. Her latest grant helps take critical forward steps, from studying slices of brain tissue to intact, living models." Dr. Harris' stud...Gene-altered mouse is model for rare autoimmune syndrome
...l models lacking the gene we would not only better understand its role in immune development, but see disease ch... was suspected," he said. "For example, we need to understand why autoimmunity so specifically affects the lachrymal and salivary glands when the Id3 gene is very...Gene for Joubert syndrom with excessive brain folds discovered by UCSD researchers and Harvard team
...lso have autism, Gleeson explained that "if we can understand how the AHI1 gene works and how its dysfunction leads to disordered brain development, it can tell us something about the biology underlying a common disorder like autism." Also important are the implications for genetic testing, Gleeson adde...Genetic data crunching achieves milestone at Stanford
...n. Microarray data have also allowed scientists to understand how various drugs affect the malaria bug, to find out what the immune system attacks in patients with autoimmune diseases and to pinpoint genes involved in multiple sclerosis. Sherlock estimates the database now supports 400 campus researchers doing ...Babies born after surgery on eggs
... but he has concerns. He points out that we do not understand the consequences of moving mitochondria from one cell type to another. For instance, in eggs and early embryos mitochondria do not replicate, while they do in granulosa cells. More seriously, he says the group should have done more extensive experime...For inferring the biological tree of life, simple is better
... phylogenetic methods with experimental studies to understand how genes evolve new functions. He is particularl...e laboratory and expressed it in cultured cells to understand its function, work that was published in the journal Science. He also is an expert in environmental ...OHSU study: Bacterial switching mechanism key to survival
...lography helps all biomedical scientists to better understand its function. "Our major focus is to determine str...nd their biologically relevant complexes so we can understand the biology more completely," he said. "My lab focuses on bacterial systems. If you can understand t...New genomic method can identify disease-causing genes
...ics at Roche Palo Alto. "It will help researchers understand the relationship between trait differences and variations in the mouse genome, which will move us a long way toward understanding the impact of human genetic differences. As that happens, we should be able to translate genetic data more effectively a...Mouse study: 'Critical' Down syndrome region isn't
...eat the problems seen in Down syndrome, we need to understand what is really happening and when in development it happens. "Until very recently, we wouldn't have even thought it possible to 'treat' Down syndrome problems," he adds. "The task seems insurmountable -- the genetic problem is there from conception, ...UF scientist: 'Brain' in a dish acts as autopilot, living computer
...ching the brain cells interact, scientists hope to understand what causes neural disorders such as epilepsy and ...st starting out. But using this model will help us understand the crucial bit of information between inputs and the stuff that comes out," he said. "And you can i...Latest buzz in research: Intoxicated honey bees may clue scientists into drunken human behavior
...eins in the honey bee brain may help us eventually understand how alcoholism affects memory and behavior in humans, as well as the molecular basis of addiction." The researchers presented their work on October 23 in San Diego at the annual Society for Neuroscience conference. Honey bees were secured into a smal......re affected in the autistic brain, we can begin to understand the underlying mechanisms that give rise to the be...at smaller range may indicate a reduced ability to understand a complex, fast-moving human speech stream. For example, to accurately decode speech, we need to be ...Calorie restriction leads to some brain benefits but not others in mice
...Annual Meeting in San Diego. "Our findings help us understand the processes underlying both normal aging and cal...need to do bigger, more extensive studies to fully understand these findings, but the bottom line is that you don't get uniformly positive results from calorie re...Pesticides may promote Parkinson's disease and exercise may offer protection
...o Parkinson's disease is helping scientists better understand some of the mechanisms of this serious and disabling brain disorder, which affects about 1 million people in the United States. Knowledge of the environmental factors and genetics of this illness has allowed investigators to create models of disease ...Soaking up signal: Endocytosis controls spreading and effective signaling range of Fgf8 protein
... of target cells are unknown. In seeking to better understand how this signaling is controlled, researchers Steffen Scholpp and Michael Brand of the University of Technology, Dresden and the Max Planck Institute-CBG, Dresden, have investigated the role of Fgf8 in the development of nascent neuroectoderm tissue ...New center to map DNA of key lab mice
...n extension of the Institute's ongoing research to understand the genetic basis for differences in response to d...over the complex interplay among genes in order to understand how diseases develop. Examples of diseases targeted for study include: cancer, Parkinson's, Alzheim...Medical informatics project targets ovarian, breast cancers
..., $8 million project that will help doctors better understand the damage caused by breast and ovarian cancers. Funded by the National Cancer Institute, the project will bring together clinical and basic science cancer researchers at the IU School of Medicine and the IU Cancer Center in Indianapolis and the Medi...Clues to the puzzle of 'talking' root cells
...th. In their studies, the researchers sought to understand details of how a protein made by a gene called Short-Root travels from one cell to another in the developing plant root. In previous studies, Benfey and his colleagues made the surprising finding that the Short-Root protein is one means by which one ...Yerkes researchers to present array of new data at Society for Neuroscience Meeting
... addiction. The data will help researchers further understand the neurochemical changes that underlie addiction ...tween the hypothalamus and CART in order to better understand and ultimately control appetite and addiction. (6 p.m. 7 p.m.) October 26, 2004 Each ......ould be the methods considered. "We don't really understand the link between the two conditions although some biochemical mediators have been implicated. It is possible that systemic spreading of prostaglandins produced by endometriosis may contribute to migraine and it has also been shown that upregulation o...