Tag: "understand" at biology news
Vollum Institute discovery may unlock human genome
...ompleted early last year. "The question was how to understand
the enormous amount of genomic information that ha... the relationships between identified genes and to understand
how complex patterns of gene expression take place. But the Goodman lab's discovery, Ginty said, wil...
Mouse brain tumors mimic those in human genetic disorder
... with NF1, and studying those tumors has helped us understand
the cellular events involved in NF1 brain tumor development," says principal investigator David H. Gutmann, M.D., Ph.D., the Donald O. Schnuck Family Professor of Neurology. The study appears online and will be published in the January 2005 issue of ...
Brain tumor study reveals why treatment efforts fail in genetic disorder
... neurofibromatosis tumors, and may help scientists understand
other cancers related to RAS. "The downside is our...unately, the results have been disappointing. To understand
why, Gutmann's team examined whether all forms of RAS are overly active in mouse cells lacking both ...
A key signaling molecule in osteoarthritis is identified
... critical in this sequence may not only help us to understand
the disease better, but may also provide information for the design of new therapeutic strategies for the treatment of osteoarthritis." Dr. Li and his colleagues found that the mutant mice had increased amounts of the protein discoidin domain recep...
Genome comparison of four campylobacter strains yields new genetic markers and clues to virulence
...ons" and other gene variations may help scientists understand
why there are major differences in the biology of ...ts also say the study has helped scientists better understand
the evolutionary relationships among Campylobacter species. In addition, the phage and megaplasmids ...
DNA movement linked to formation of antibody genes
...roduction of antibodies. This will help scientists understand
the mixing and matching of DNA in all organisms and the role this mixing plays in healthy and diseased cells. Nancy L. Craig from the Howard Hughes Medical Institute and Department of Molecular Biology & Genetics at Johns Hopkins Medical Institute le...
MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...ambitious experimental and computational effort to understand
the quantitative behavior of a cell signaling pathway in yeast. The Alpha Project is funded by the National Institutes of Health's National Human Genome Research Institute, which designated MSI as a Center of Excellence in Genomic Research. The CEGS ...
No blind mice, thanks to UF scientists
...e at work during retinopathy and it's important to understand
each of them," Sheibani said. "It's interesting that the researchers show how SDF-1 changes the levels of a protein called occludin, which affects junctions between cells that line the blood vessels. It helps explain why the blood vessels become leak...
New method simplifies search for genetic changes associated with disease
...ease, providing them the leads they need to better understand
and treat a wide range of disorders. Researchers report in the January issue of Nature Methods that they've already applied direct genomic selection to a region of DNA linked to psoriasis, a disfiguring and potentially debilitating inherited skin con...
Researchers tease out one critical role of tumor-suppressor gene
... Rb works in normal cells could help us to someday understand
how tumor-suppressor genes function in tumor devel... mutates. It could also ultimately help scientists understand
how other types of cancer progress. "Cancer cells are altered in so many different ways that it's ha...
Mutations in transporter protein shed light on neurodegenerative disorders
...n addition to the Finnish mutation." To better understand
how mutations in sialin cause the two diseases, Dr. Reimer and his colleagues at Stanford altered part of the sialin molecule, causing it to be expressed on the surface of cells rather than inside lysosomes. In doing this, the researchers were able t...
Gorillas in the midst of extinction
...s. NASA satellite imagery helps scientists better understand
land changes in the Virunga Conservation Area which covers the Virunga National Park in the Democratic Republic of Congo (DRC), the Mgahinga Gorilla National Park in Uganda and the Volcanoes National Park in Rwanda. In Swahili, the word virunga means...
Queen's discovery sheds new light on ancient temperatures
...ancient history of the planet," says James. "If we understand
what has happened in the past and how the earth has responded and recovered, it will give us some idea of how the world will respond to some of the things that are happening to it now." The researchers discovered ikaite at several different levels in...
Cleft palate research receives 200,000 award
... treatment and speech therapy but the more that we understand
about the way the palate develops normally, the more we can begin to analyse how and why congenital malformations such as cleft palate occur." Dr Dixon, who was recently appointed to a Lectureship in Basic Dental Sciences, has been awarded more than ...
New family of genes could serve as a potential cancer marker
...is going to add another critical tool in trying to understand
the errors of genetic language and the progression of cancer, therefore giving researchers possible new solutions to reversing this dreadful disease."...
Searle grant funds proteomics initiative
...CBC liaison. "It is a shift to wellness. If we can understand
proteins and their interactions, we can use protei...a trillion or more proteins, scientists seeking to understand
this complexity face a research challenge of enormous magnitude. Through the CBC's research collabor...
Scientists reveal molecular secrets of the malaria parasite
...rasites' complex life cycle is helping researchers understand
when different genes switch on and off as the pathogens metamorphose through seven different life stages. In turn, that molecular-level data may benefit biomedical scientists who are identifying new targets for vaccines that would impede the parasite...
Can plant research lead to new insights in cancer research?
...th a partner in cancer research in order to better understand
the factors that underlie cancer....
Healthy cleavage: How statins protect against Alzheimer disease
...(non-amyloidogenic) cleavage. In their quest to understand
how statins affect APP processing, Gandy and colleagues focused on a molecule called ROCK, a kinase enzyme that had recently been implicated in APP processing. Working in mouse neuroblastoma cells, they confirmed that two different statins increased ...
Unusual reproductive behavior of odd ants surprises scientists
...we gain access to more and more tools that help us understand
what's going on at the molecular level, we'll likely find that a lot of social insects and other animals aren't conforming to our predictions and expectations." Rissing and Cahan conducted this study with Glennis Julian of the University of Arizona, ...
1 2 3 4 5 6 7 8 9 10