Tag: "unmask" at biology news
News tips from the Journal of Neuroscience
...nd Jakob B. Srensen This week, Gulys-Kovcs et al. unmask
a dual role for Munc18 in docking and priming of vesicles in chromaffin cells. In vitro , Munc18 binds the "closed" state of syntaxin1 and thus occludes binding of the SNARE proteins SNAP-25 and synaptobrevin. However, Munc18 cannot be simply a nega...
Analysis reveals extent of DNA repair army
...cell's response to DNA damage has the potential to unmask
the molecular interplay at the root of many diseases and conditions. "These things are really important," he said. "This is how things get coordinated and how the different repair pathways are activated. Every time you duplicate a cell, there are eno...