Researchers discover inherited mutation for leukemia
...ylation. Healthy cells use this process to silence unneeded genes. But abnormal DNA methylation can turn off genes that control cell growth, and that lead to tumor growth. "Our findings identify for the first time a gene that appears to be associated with hereditary CLL," says coauthor John C. Byrd, profes...Popular herbal supplement hinders the growth of pancreatic cancer cells
...normal method of disposing of damaged, unwanted or unneeded cells. This process often is faulty in cancer cells. Results of the study, abstract number LB-142, are being presented in a late-breaking session at the annual meeting of the American Association for Cancer Research, April 14-18, at the Los Angeles C...Heart failure: Intervention possibilities from imaging programmed cell loss
...d cell lossthe body's normal way of getting rid of unneeded or abnormal cellsmay help in early identification of those individuals who are at risk of developing heart failure, say researchers in the April Journal of Nuclear Medicine. "Our study indicates that it is feasible to noninvasively identify cell lo...Prefrontal cortex loses neurons during adolescence
...n some brain regions are lost. The pruning away of unneeded or disruptive neural circuits appears to be as important to development as the growing of new neural connections, Juraska said. Although other researchers had seen reductions in the size of the cortex, "no one thought neurons were lost, unless som...Ecological change, climate variation addressed at international conference, September 20-24
...process isn't happening: the fungi are absent. The unneeded sugars are then used for increased plant growth.Without the mycorrhizal fungi to "mine" soils for organic nitrogen, there may be a long-term increase in amount of organic matter found in these soils, says John Hobbie, with unknown effects. Plant co...Keeping amyloid - and Alzheimer's - in check
...signaling. In fact, it may just be a way to remove unneeded protein stubs from cellular membranes. However, new findings from Howard Hughes Medical Institute (HHMI) international research scholar Peter St George-Hyslop at the University of Toronto argue against this hypothesis. St George-Hyslop's group recen...NJIT students present leading research during Provost's Student Research Showcase
... The technology we are developing will cut down on unneeded operations and thus be a big benefit to medicine." Aysegul Ergin, of Kearny, a doctoral student in biomedical engineering, is designing an optical glucometer that could radically improve the way diabetics manage their glucose levels. The device -- ...Studies suggest new targets for tuberculosis treatments
...human cells also contain proteasomes for degrading unneeded proteins. This process is essential for human cell survival. So any drug targeting the TB proteasome would have to be extremely specific. This was one reason for conducting such detailed structural and biochemical studies, to try to identify the uniq...Bacterial protein mimics host to cripple defenses
...otential cancers in the bud, and get rid of old or unneeded cells. However, runaway PCD leads to everything fr...cells use to attach the small protein ubiquitin to unneeded or defective proteins. Other enzymes then chew up and "recycle" the ubiquitin-tagged proteins. To c...Study finds protein is required for human chromosome production
...enger RNA molecule in two, but also then chews the unneeded portion of the histone mRNA molecule into pieces. It is rare to find two such activities within a single protein, Dominski said. "From the point of view of understanding biology, our findings provide a unified mechanism for the synthesis of all messe...Cellular dumping site is not garbage after all
... can bypass the assembly plant altogether and send unneeded mRNAs straight to P-bodies to be degraded or eventually recycled. Parker said his lab's next step is examining the potential role of P-bodies in memory and in viral infections....Failure to dispose of unneeded cells during development linked to cancer
...ions in these genes disrupt the normal disposal of unneeded or damaged cells during development, thereby allowing potentially dangerous premalignant cells that should not have survived to persist. The mechanism described in the work, published in the August issue of Cancer Cell, may play a role in other form...U-M scientists see ubiquitin-modified proteins in living cells
...tin was simply a universal "destroy me" signal for unneeded or harmful proteins, but it has recently been found to be associated with many other cellular functions. "The same ubiquitin signal can cause one protein to be degraded, but another protein to be moved to a new location," Kerppola says. "We're in...