Brain-mapping technique aids understanding of sleep, wakefulness
...in sleep, he said, his and other studies will help unravel the mechanisms involved in sleep homoeostasis. In addition to his laboratory at UT Southwestern, Dr. Yanagisawa also directs the ERATO Yanagisawa Orphan Receptor Project in Japan, where these studies were carried out. He and his colleague, Dr. Takes......ic DNA sampling is part of a larger undertaking to unravel the origins and migratory history of mankind thousands of years back in time by analyzing genetic samples from at least 200,000 people all over the world. National Geographic and IBM are embarking on the Genographic Project, a landmark, five-year glo...Ebola virus: from wildlife to dogs
...ntists and their partners (1) have been working to unravel the virus's biological cycle, in other words the whole range of ways in which the virus circulates in its natural environment, from its natural host (or reservoir) right up to humans. They showed that strong epidemics of Ebola have decimated populati...Satellite images give a better picture of sediment transport
...ars been applying modelling techniques in order to unravel the system of current circulation and sediment transport (1). Satellite remote sensing provides reliable quantified data on the concentration of suspended matter in water. The researchers compared the data transmitted by the Landsat satellite with fi...JCI table of contents April 1, 2005
...f North Carolina use a mouse model of pemphigus to unravel the mechanisms of this disease. The researchers show that activity of a protein called plasmin is an essential step in the early phase of blister formation in the mouse model. They further show that plasmin joins another protein, MMP-9, in a pathol...Researchers identify cause of 'early bird' sleep disorder
...search team wrote in Nature. Such studies may help unravel some of the fundamental mysteries of how circadian rhythms are established and maintained in creatures that have evolved along very different paths.As for the affected individuals, Ptacek said most are able to live normal lives, and some are proud of...UCSD researchers maintain stem cells without contaminated animal feeder layers
...or in mediating these cellular events will help to unravel the biochemical pathways responsible for 'stemness'. An increased efficiency in the generation and culture of human stem cells for potential clinical applications is timely, given the recent report of 17 newly derived stem cell lines available for n...Conserved amino acids play both structural and mechanistic roles in sandwich-like protein
...ize the final protein structure? In our paper, we unravel an unprecedented answer to this question." Wittung-Stafshede and graduate student Corey Wilson analyzed the purpose of six of the eight amino acids by exchanging a nonessential amino acid for each of them and monitoring the effect on the protein stru...Signaling protein builds bigger, better bones in mice
... she says. In future research, MacDougald hopes to unravel the molecular mechanism for Wnt10b's bone-building effect. "It's not only an important scientific question, it's important to the understanding and potential treatment of osteoporosis and other human diseases," he says. "Right now, there is a need f...Prehistoric jawbone reveals evolution repeating itself
...id. "Only the evidence of fossils has been able to unravel this tangled history of a complex adaptation." Anne M. Musser, Ph.D., of the Australian Museum and Timothy F. Flannery, Ph.D., of the South Australian Museum also were co-authors of the paper....PET/MRI scans may help unravel mechanisms of prenatal drug damage
... mother and her fetus during pregnancy may help us unravel the mechanisms of the drug's damaging effects on unborn children," said SNM member Helene Benveniste, M.D., Ph.D., chair of Brookhaven's medical department in Upton, N.Y., and lead author of the paper, "Maternal and Fetal 11C-Cocaine Uptake and Kinet...Steroid discoveries could add bulk to crop harvests
...these two articles is that we are now beginning to unravel the molecular mechanisms by which steroid hormones regulate gene expression in plants," said Chory, who is at The Salk Institute for Biological Studies. The first study reveals how plant steroid hormones, called brassinosteroids, plug into and activa...Scientific heavyweights to speak at Jan. 28 Hopkins symposium
...ed saw scientists blend traditional disciplines to unravel basic genetic functions. These efforts were reward...,' is beginning as researchers use genomes to help unravel fundamental biological and disease processes," says symposium co-organizer Aravinda Chakravarti, Ph....Deciphering the genetic babel of brain cells
...the scientists report using their new technique to unravel the genes that are active in corticospinal motor neurons (CSMN), which connect the cortex and spinal cord and carry the signals that operate muscles. These neurons are important because their degeneration contributes critically to amyotrophic lateral...Research may speed development of new oral drugs for fertility treatments
...eprint of FSH and its receptor because it may help unravel the structural framework of a trio of other hormones, notably, luteinizing hormone (LH), chorionic gonadotropin (CG), and thyroid-stimulating hormone (TSH). Hendrickson acknowledges that many biochemical studies by other researchers contributed piece...Queen's discovery sheds new light on ancient temperatures
...e of the main thrusts of our research is trying to unravel the ancient history of the planet," says James. "If we understand what has happened in the past and how the earth has responded and recovered, it will give us some idea of how the world will respond to some of the things that are happening to it now....Vollum Institute discovery may unlock human genome
... map them to the entire genome. Our work will help unravel the genomic instruction set that governs how genes are regulated in a given cell type. If one views the genome as a multidimensional puzzle, our method helps make the puzzle a little simpler." The discovery already has demonstrated its implications f...Scientists find impaired chromatin structure formation & imprinted gene involvement in Rett Syndrome
...ow them the opportunity to continue their work and unravel if and how DLX5 contributes to Rett Syndrome symptoms," said Monica Coenraads, co-founder and Director of Research for RSRF. Future experiments will include the analysis of gene expression in the neighboring chromatin affected by the loss of the sil...Genetic discovery paves way to decode sense of smell in mammals
...he finding in mice paves the way for scientists to unravel the underlying code that allows the brain to interpret smells, according to the researchers. Using genetic manipulations, the team found two proteins in mice that chaperone odorant receptors to the surface of olfactory nerves in the nose. Odorant rec...... break, you can imagine that the nucleosomes might unravel and the stacking of the nucleosomes fall apart, exposing the site that 53BP1 recognizes," Halazonetis says. "This is the model we are proposing for how cells sense the presence of DNA breaks to activate the p53 pathway."...