Tag: "variant" at biology news
Drug lowers inflammatory markers associated with risk for heart attack
...y previously reported the identification of a gene variant
that predisposes patients to MI. The gene encodes ...ipoxygenase activating protein (FLAP) and its risk variant
results in an almost 2-fold increased risk of MI. Hakon Hakonarson, M.D., Ph.D., of Decode genetics ...
To stop evolution: New way of fighting antibiotic resistance demonstrated by Scripps scientists
...to rifampicin or ciprofloxin, when they harbored a variant
of LexA that was catalytically inactive. In control experiments, the rodents were given rifampicin or ciprofloxin, and the scientists found that nearly all the wild-type E. coli cells had grown fully resistant to the antibiotics after three days. ...
NIMH research showcased at APA meeting
...by which nurture can modify nature A suspect gene variant
that boosts risk for psychosis triggers a telltale pattern of brain activity. Certain subgroups of teens with depression may respond better than others to treatment. "We view our research track at the APA meeting as an extraordinary opportunity to...
Tendency to hair loss inherited from the mother
...ected lay the gene for the androgen receptor. "One variant
of this gene was found among men who suffered from...rogen receptors in the scalp Probably the genetic variant
results in more androgen receptors in the scalp. "Our findings permit two explanations," Axel Hillme...
First technology to remove prions that cause vCJD from blood launched
...5)-- The risk of receiving blood contaminated with variant
Creutzfeldt-Jakob (vCJD) prions may no longer be a concern for the thousands of people who require a transfusion. Pall Corporation (NYSE: PLL) announced today the Council of Europe (CE) marking of its Leukotrap Affinity Prion Reduction Filter System...
New finding in studying dopamine transporter
...der (ADHD). "Healthy people who carry a particular variant
of the dopamine transporter gene, the nine repeat ...r, M.D. "We are not yet sure if the effects of the variant
on transporter levels in our healthy subjects can be generalized to neuropsychiatric disorders," van...
Marshfield Clinic researchers launch study of environmental causes of Alzheimer's disease
... to consider more than one factor because one gene variant
by itself may not confer a detectable risk of gett...even the most probable genetic link, APOE4, a gene variant
of the protein APOE that functions in the transport of cholesterol and phospholipids, is estimated t...
Gene variant linked to chronic kidney disease
...chool of Public Health and other institutions. One variant
increases risk and the other decreases risk with a...site direction. Results of the study found that a variant
of the APOE gene, the e2 allele, was associated with a moderately increased risk for chronic kidney ...
Arsenic - not the same for everyone
...y given gene, we ask, 'Do people with one sequence variant
metabolize arsenic differently than people with an...nly be found in children. Adults carrying the same variant
of CYT19 do not metabolize arsenic differently. "Apparently the genetic variation affects arsenic me...
Study in Royal Society journal on holly as an indicator of climate change
...s variable MHC genes. Furthermore, we found that a variant
of a specific MHC gene gave the same protection. Hence, genetic factors are important for survival in birds.Contacts: Dr H Westerdahl, Animal Ecology, Lund University, Ecology Building, LUND, 22362, Sweden Environmental quality and evolutionary pote...
New results validating Pall prion reduction filter disclosed at ISBT Congress
...o blood services worldwide as new threats, such as variant
Creutzfeldt-Jakob Disease (vCJD), emerge. An update on the latest measures to protect the public from the human form of Bovine Spongiform Encephalopathy (BSE), commonly called Mad Cow Disease, and minimize risk of transmission through blood transfus...
Other highlights in the July 6 JNCI
... familial melanoma in individuals who carried MC1R variant
genotypes when compared with carriers of the wild-... They also report that individuals who carry MC1R variant
genotypes were more likely to have thick melanomas than those with the wild-type MC1R genotype. In c...
DNA meets heart drugs with resistance
...f a structural motif in the C-terminus. Thus, the variant
channel is distinguishable from wild-type only with drug exposure, and this variable drug access to its target binding site is through a mechanism has not previously been reported for ion channels....
Asthma, allergies may reduce risk of brain cancer
...f the journal Cancer Research. The kind of genetic variant
Schwartzbaum is talking about is called a polymorphism. While a mutation consists of a rare and abnormal DNA pattern, a polymorphism consists of common patterns, each considered normal. "We needed an objective way to measure the accuracy of allergy s...
Multiple genetic 'flavors' may explain autism
...ow well they functioned. With the exception of one variant
common to both studies, most of these variants had...sly linked to any clinical conditions. While the variant
SERTs could perform their basic function of 'vacuuming' up excess serotonin, intracellular signaling...
Toxins drove evolution of human taste sense, global study reveals
...e that release cyanide when digested. The receptor variant
also is more sensitive to certain beneficial compo...umans out of Africa. Further study of the receptor variant
found that K172N had a clear effect on receptor function. In particular, taste receptors carrying th...
Report recommends renewed focus on food and agriculture research
...tato famine in Ireland in the 19th Century. A new variant
of the blight emerged in the United States in the 1980s causing serious losses and even bankruptcy for some potato growers. Microorganisms continue to cause harm to the food supply beyond the farm, causing spoilage and, in some cases poisoning and d...
Corn grain mould used as pesticide
...n with Beelzebub. "Apart from that the aspergillus variant
has to be so sturdy that it can assert itself against its toxic cousin in the wild," Professor Sikora says. Promising strains among 3,000 isolates The Federal Ministry of Economic Co-operation and Development (the BMZ) is supporting the project unt...
Gene's discovery could help prevent a leading cause of blindness in the elderly
...ty used similar methods to identify the first gene variant
thought to be a major contributor to ARM, complement factor H (CFH) on chromosome 1. The Pittsburgh study confirms involvement of this gene and, for the first time, shows that the association results also accounted for findings from previous genetic ...
'Mad cow' proteins successfully detected in blood
...vine spongiform encephalopathy (BSE) in cattle and variant
Creutzfeldt-Jakob disease (vCJD) in humans. The blood test would make it much easier to keep BSE-infected beef out of the human food supply, ensure that blood transfusions and organ transplants do not transmit vCJD, and give researchers their first c...
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