Tag: "variant" at biology news

Gene variation affects pain sensitivity and risk of chronic pain

A new NIH-funded study shows that a specific gene variant in humans affects both sensitivity to short-term (...ors also may be able to screen people for the gene variant to predict their risk of chronic post-surgical pain before they undergo surgery. The results appear...

Diabetes gene carries similar risk to obesity

Carrying two copies of a common variant of a particular gene doubles your chances of devel... UK for 15 years, and found that carrying a common variant of the gene increased their risk of developing diabetes by 50 per cent. Carrying two copies of the v...

Scientists find gene target that may protect against Crohn's disease and ulcerative colitis

...iguing because we appear to have identified a gene variant that protects against development of IBD," said Dr. Cho, who is also director of the Inflammatory Bowel Disease Center at Yale. While mutations of the gene which codes for a receptor in a major inflammatory pathway are strongly associated with Crohn...

New gene found for Crohn's disease

...iguing because we appear to have identified a gene variant that protects against development of IBD, a finding that may lead us to think about the genetics of health as much as about the genetics of disease," said Dr. Cho, who also is director of the Inflammatory Bowel Disease Center at Yale. The study's a...

Crohn's disease gene identified

...iguing because we appear to have identified a gene variant that protects against development of IBD," said Ch...ifferences in the CARD 15 gene, they found a third variant SNP, which was in a different gene on a different chromosome--the interleukin-23 receptor. "We kn...

Scientists find major susceptibility gene for Crohn's disease

...iguing because we appear to have identified a gene variant that protects against development of IBD, a finding that may lead us to think about the genetics of health as much as about the genetics of disease," said Dr. Cho, who also is director of the Inflammatory Bowel Disease Center at Yale. Because IBD t...

ACS News Service Weekly PressPac -- Oct. 25, 2006

...reaks down acetaldehyde. Individuals with the gene variant produce little aldehyde dehydrogenase and high levels of acetaldehyde build up in their blood after alcohol consumption. Millions of people have the gene variant, which occurs mainly in individuals of East Asian heritage. "Taken together, the observ...

Gene linked with mental illness shapes brain region, researchers find

DALLAS Nov. 7, 2006 -- A gene variant associated with mental illness goes hand-in-hand with enlargement of a brain region that handles negative emotions, researchers at UT Southwestern Medical Center and the Central Texas Veterans Health Care System have found. The region of the brain...

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

...reast cancer cells in mice. CDDO and its synthetic variant CDDO-ME are undergoing clinical trials for leukemia and solid tumors. Beginning at 10 weeks of age, mice that were genetically altered to become susceptible to breast cancer were fed either a control diet, a dose of CDDO-ME, LG 100268, or a combin...

Diet can provide protection against development of certain cancers, new studies show

...he interaction between vitamin E and GSTM1, a gene variant known to produce enzymes that efficiently detoxify carcinogens in tobacco smoke, and found a greater effect of the vitamin among men with this gene. "We all want to know if vitamins help protect us against disease, and measuring their effects in th...

Gene linked to aggressive 'wet' age-related macular degeneration

A gene variant that increases the risk of developing the aggressi...nd that both wet and dry AMD are associated with a variant in the complement factor H (CFH) gene on chromosome 1. Hoh now reports they have found a single nu...

Living view in animals shows how cells decide to make proteins

...use the exons presence or absence determines which variant of the FGFR2 protein is produced, she said. Such subtle variations in proteins can alter the cells behavior, just as switching ingredients in a favorite recipe can change the foods flavor, according to the scientists. "Viewing these decisions is mo...

Evolution of influenza A virus

...fecting a host or the introduction of a particular variant from elsewhere. These factors make predicting future patterns of influenza virus evolution more difficult, as vaccine strain selection then becomes dependent upon intensive surveillance, whole-genome sequencing, and phenotypic analysis....

New approach to BSE successful in lab

... this years Nobel Prize for Medicine. Scrapie is a variant of the cattle disease BSE and the human equivalent...on protein is known as PrP-Scr, whereas the normal variant is PrP-C. PrP-C seems to have a protective effect in diseases like a stroke. Interestingly, mice whi...

Study reveals molecular basis of botulism toxin's deadly activity

... may be able to engineer toxins that bind to these variant receptors....

Gene tied to longevity also preserves ability to think clearly

December 25, 2006 -- (Bronx, NY) -- A gene variant linked to living a very long life--to 90 and beyon...his colleagues had previously shown that this gene variant helps people live exceptionally long lives and apparently can be passed from one generation to the n...

Longevity gene also protects memory, cognitive function

...of the American Academy of Neurology. The gene variant alters the cholesterol particles in the blood, mak...were 95 years old or older. Those who had the gene variant were twice as likely to have good brain function compared to those who did not have the gene variant...

Genetic mutation alters response to heart failure drugs

...beta blocker. Engelhardt and colleagues examined variant beta1-adrenergic receptors in which the amino acid...toprolol, and carvedilol on the Arg389 and Gly389 variant beta1-adrenergic receptors in rat cardiac cells. They found that while each of these drugs caused a ...

JCI table of contents: January 2, 2007

...beta blocker. Engelhardt and colleagues examined variant beta1-adrenergic receptors in which the amino acid...toprolol, and carvedilol on the Arg389 and Gly389 variant beta1-adrenergic receptors in rat cardiac cells. They found that while each of these drugs caused a ...

Other highlights in the January 3 JNCI

...study raises the possibility that some mutation or variant on the Y chromosome may be involved in prostate cancer. Although several studies have identified risk factors for prostate cancer and found some gene mutations that are associated with the disease, none of these can account for large numbers of pro...

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(Date:8/28/2014)... . Cars, planes ... of sophisticated assembly lines. Mobile assembly carriers, on to which ... assembly lines. In the case of a car body, the ... a precise spatial and chronological sequence, resulting in a complete ... of such an assembly line at molecular level has been ...
(Date:8/28/2014)... Log exports from Washington, Oregon, northern California, and Alaska ... second quarter of 2014, an increase of more than ... the U.S. Forest Service,s Pacific Northwest Research Station reported ... decreased by 4 percent to 247 million board feet. ... by more than 5 percent to $390 million in ...
(Date:8/28/2014)... will be fully saturated with pests by the middle ... a new study led by the University of Exeter. ... found in around half the countries that grow their ... rate, scientists fear that a significant proportion of global ... next 30 years. , Crop pests include fungi, bacteria, ...
Breaking Biology News(10 mins):Nanoscale assembly line 2Nanoscale assembly line 3West coast log exports up, lumber exports down in second quarter of 2014 2New study charts the global invasion of crop pests 2
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