International team finds gene variants that affect response to HIV infection
...rson resists infection with human immunodeficiency virus (HIV). Their work shows that mothers with a specif... molecules grab pieces of the proteins made by the virus and display the protein fragments on their surface. Other immune system cells recognize the foreign ...Chicken genome analysis will benefit human health and agriculture
...t we want to look at whether it's resistance to a virus or how the bird responds to a new type of feed we can hone in on the genetic component." He compared biologists' knowing the genome sequence to a sociologist's wanting to study the population of New York City and using a telephone director...Study identifies key aspect of immune response against HIV
... a key role in the body's defense against HIV, the virus that causes AIDS. The findings may lead to ways o...s of HLA-B were associated with high or low plasma virus levels. Additional tests that looked at levels of the helper T cells that are destroyed by HIV and t...Gene therapy reduces skin cancer to sunburn in mouse model
...f mouse Xpa into the mutant mice, using a disabled virus that infects multiple cells. They then exposed the...foreign genes. Also, infection of the skin with a virus carrying the gene of interest, as we did with the mice, allows for many, many cells to receive the a...Purdue scientists hunt for 'secret X' to treat liver cancer
...ri-SAH-nee) has shown that a protein the hepatitis virus instructs chronically infected liver cells to prod... Cellular Biology. Viruses like the hepatitis B virus incorporate their genes into a healthy cell's genetic material. This way, many viruses not only inst...JCI table of contents, December 15 2004
.../12/1704 . Immune cooperation foils influenza A virus infection Influenza A virus (fluA) is a major human pathogen. The role of certain white bloods cells, known as natural killer (N...Encouraging results of gene therapy for severe combined immunodeficiency
...row cells and spliced into a leukaemia virus. This virus was then introduced back into the patients where the gene was replicated. Almost normal immune functioning became established in all 4 patients after the procedure. Lead investigator Adrian Thrasher (Institute of Child Health, London) comments: "At l...Combined stem cell-gene therapy approach seen as potential treatment for cystic fibrosis
..., the researchers used the Maloney murine leukemia virus as a vector to shuttle the CFTR gene into the stem...ally delivering them to patients. In addition, the virus vector being studied by Dr. Kolls is bigger than others being used in trials and has the capacity fo...Tips from the Journals of the American Society for Microbiology
... issue of the Journal of Virology. Herpes simplex virus type 2 (HSV-2), or genital herpes, is a virus that infects approximately 22% of adult Americans. Bearing physical, psychological, and social effe...An unusual RNA structure in the SARS virus offers a promising target for antiviral drugs
SANTA CRUZ, CA--Research on the genome of the virus that causes severe acute respiratory syndrome (SAR...f RNA. Their findings suggest that it may help the virus hijack the protein-building machinery of infected cells. The SARS virus is a type of RNA virus, mean...JCI table of contents, 3 January 2005
...used on increasing the turnover of latent pools of virus through activation of latent infected cells (which promotes cell death and accelerates viral clearance) and combining this approach with intense antiretroviral therapy. In the January 3 issue of the Journal of Clinical Investigation, Roger Pomera......used on increasing the turnover of latent pools of virus through activation of latent infected cells (which promotes cell death and accelerates viral clearance) and combining this approach with intense antiretroviral therapy. In the January 3 issue of the Journal of Clinical Investigation, Roger Pomerantz,...Protein transformation gives new twist to medical research
...a that try to enter the eye. But Lyz is made by a virus growing inside the bacterial cell. The virus has to destroy the cell wall, or the virus babies would be trapped inside the dead body of the bac...Scientists discover key genetic factor in determining HIV/AIDS risk
...ht HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Ins...Novel antiviral technology inhibits RSV infection in mice
...hnologies thwarts attacks of respiratory syncytial virus (RSV) -- a virus associated with severe bronchitis and asthma, an animal study by University of South Florida researc...UCI researchers create new technique for speeding development of vaccines
...mong a total of 200 proteins that make up the live virus that is used to vaccinate against smallpox today. Humans react strongly only to these 11 proteins, explained Philip Felgner, principal investigator of the research project and director of the proteomics laboratory within the Center for Virus Research...Columbia research lifts major hurdle to gene therapy for cancer
...orporating it into a specially designed virus. The virus eradicated prostate cancer cells in the lab and in...a), skin (melanoma) and colon cancer - because the virus is constructed to exploit a characteristic of all solid cancers. "What's exciting is we may now be a...US government list of cancer-causing agents grows
...e been added to the "known" category: Hepatitis B virus (HBV) and hepatitis C virus (HCV) are viruses that cause acute or chronic liver disease. They are listed in the report as "known......this approach "may serve to turn the tables on the virus by interfering with the very pathways that are req...de C promoter triggered massive replication of the virus in cells and during primary infection in monkeys. The preferential replication of clade C in primar...Blocking cell signaling can stymie viral infections, study shows
... movement the actual steps that take place once a virus has invaded the body." In the study, Reinherz ...nkey kidney cells, the drug prevented the smallpox virus from spreading to other cells. In lab mice infected by a virus similar to the smallpox virus, a comb...