Virus-host interactions at sea effect global photosynthesis
...s-related genes, some of which could mean that the virus helps the host maintain photosynthesis during infe...hesis, which the authors speculate could allow the virus to reproduce in nutrient-poor environments, and all three cyanophages carry genes involved in metabo...Friendly bacteria in humans may protect against HIV
...do not cause disease. They target HIV because the virus is coated with the sugar mannose, which they use a...revealed two strains that specifically trapped the virus and blocked infection. Due to high rates of mutation, repeated attempts at developing a vaccine to p...Scientists infuse rat spinal cords with brain-derived human stem cells
...the cells were infected, the scientists washed the virus away, leaving self-sustaining colonies of GDNF-producing progenitor cells. The next problem was actually getting the cells into the right location of the ALS rat spinal cord. "Nobody had shown that human progenitors could be delivered right into th...Other highlights in the April 20 JNCI
...VPositive Women Women with human immunodeficiency virus (HIV)/AIDS have high rates of human papillomavirus (HPV) infection and an elevated risk of developing cervical cancer. However, information is lacking regarding several fundamental aspects of the association between HIV and HPV infections. A new stud...Turning viruses into allies against cancer
...ges of development, including modifications of the virus that causes measles and another, the herpes simple... cancer. In early clinical studies, the engineered virus -- developed by Biovex Ltd. under the trade name OncoVEX -- showed promise of causing necrosis (deat...Molecule on immune cells linked to sexual transmission of HIV
...ndritic cells may cut their ability to smuggle the virus into other immune cells. Published in the May edition of the Journal of Virology, the discovery may lead to new drugs to prevent sexually transmitted HIV infection. "Dendritic cells act like sentries to alert the immune system when a foreign agent tr...Researchers uncover sequence of major rice pathogen
... what Dean calls "hot spots" in the genome. "These virus remnants live in discreet parts of the genome and have high rates of recombination, which may be why the fungus can evolve new strains so quickly," Dean says. M. grisea undoubtedly produces toxins which may enable it to be a more effective pathogen. ...Researchers make gains in understanding antibiotic resistance
...the drugs attack several sites at once. And if the virus mutates to avoid the effects of one drug, it still gets hit by another. However, in the case of these antibiotics, the binding sites are linked in one molecule. It's like a multi-drug treatment, but in one compound," he said....Viral protein influences key cell-signaling pathway
... shows that a protein produced by a cancer-causing virus influences a key signaling pathway in the immune cells that the virus infects. This stimulates the cells to divide, helping the virus spread through the body. The study,...Respiratory syncytial virus poses a significant threat to elderly
Respiratory syncytial virus (RSV), primarily seen as a cause of illness in inf...old, but they are more severe and last longer. The virus is highly contagious, entering the nose or eyes by hands and by direct contact with residue from cou...ASU researcher creates novel 'bioelectronic signatures' to detect DNA mutations
...daptable for identifying protein targets or single virus molecules, which is what makes it suitable for diagnosing genetic diseases, detecting infectious agents and providing reliable forensic analysis. In addition, the technology is scalable for the so-called "high throughput," or large-scale DNA sequenci...Blocking COX-1 slows tumor growth in mice
... induce ovarian cancer in a mouse model by using a virus to deliver two cancer-causing genes into ovarian surface epithelial cells that lacked a tumor suppressor gene. In the current study, the Vanderbilt researchers used Orsulic's model to test whether celecoxib (Celebrex), a selective COX-2 inhibitor, a...JCI table of contents May 2, 2005
...d on the cell surface, a process that benefits the virus in a novel immune evasion strategy. This decreas... cell surface, a process that can only benefit the virus in infected cells?" TITLE: Regulation of CD1d display and function by a herpesvirus infection AUTH...Identification of specific genes predicts which patients will respond to Hepatitis C treatment
...s a disease of the liver caused by the hepatitis C virus (HCV). About 230,000 Canadians are infected with i...feron. This treatment can currently get rid of the virus in only roughly 50% of persons infected with genotype 1, the most common genotype in North America a...Discoveries by UAB and Florida scientists may help transplanted organs survive longer
...y, Atkinson said, "was the use of adeno-associated virus as a way to deliver IL-10 into the body, allowing sustained levels of the molecule to be persistently secreted into the blood stream. The next step will be to evaluate the treatment to try to protect kidney transplants in non-human primates and if s...Cancer exploits the body's wound-healing process
...tional Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding. However, the biological mechanism for this process hasn't been clear. Now, through studying ...ESA's Epidemio and Respond assist during Angolan Marburg outbreak
...ombating an Angolan outbreak of the lethal Marburg virus used high-resolution satellite-based urban maps pr... through a pair of ESA-led activities. The Marburg virus causes Ebola-like internal bleeding in humans, with an incubation period of between five and nine da...High fidelity keeps human DNA assembly line humming
...ions for how a normal cell forms a tumor and how a virus runs amok. The work is published in the May 13 edition of the scientific journal Molecular Cell . Behind the basic research is a story that melds exquisite nanotechnology in living systems and cutting-edge biochemistry and molecular biology with a s...Yale scientist studying virus infections named Burroughs Wellcome Investigator
.... The focus will be on the interaction of host and virus at the natural routes of entry for a variety of vi...and that would be effective at the site of natural virus entry," said Iwasaki. "Ultimately we would like to incorporate these factors into vaccine designs an...Tips from the Journals of the American Society for Microbiology
...icult because there are eight known strains of the virus and saliva appears to be the most prominent mode o...h valacyclovir did keep levels of the Epstein-Barr virus (EBV) strain low at both postoperative visits. EBV, the virus that causes mononucleosis, is one of ...