JCI table of contents: September 7, 2006
...mune cells coming The red, flaky patches of skin visible on individuals with atopic dermatitis and psoriasis are caused by an ongoing immune reaction in the skin. Large numbers of T cells (one of the immune cell types that causes the skin irritation) expressing a protein known as CD30 on their surface accu...Mature muscle fibers can revert to become cancerous, researchers find
...sts used the insect because its muscles are easily visible through its outer shell. The genes were linked with another gene that made cells glow green if the PAX-FKHR genes were active. They examined flies with both the PAX7-FKHR complex and PAX3-FKHR complex. Both gene complexes created fatal conditions si...Study finds how organs monitor themselves during early development
...arkers of those conditions so the results would be visible under the microscope every step of the way. Over several years, Dr. Gilboa developed both the methods and know-how to explore what she calls "a black hole": the process that transforms an embryonic ovary into an adult one. As the painstaking exper...Gabriela Cezar's stem cell research targets birth defects and cancer
...ew circles. "Gabby has given the department a very visible presence in the biotechnology and bio-business networks," Schaefer says. The department has had such visibility in the past, he notes - through the efforts of reproductive physiologist Neal First, a pioneer in cloning research, and others. "Gabby i...Alternative approaches to marine management prove successful in reef conservation
...ad higher compliance with conservation rules, were visible to the local community, and had been under management for a longer period of time than the less successful protected areas. The areas associated with the successful sites also tended to have less involvement in formal or professional economic activit...Study establishes safety of spinal cord stem cell transplantation
...erived from human embryonic stem cells suffered no visible injury or ill effects as a result of the treatment...ly injured that the transplantation does not cause visible harm and the injury is not hiding any damage the cells may have caused to the spinal cord or the sur...UCLA study finds same genes act differently in males and females
...ere not related to reproductive systems they were visible across the board and related to primary functions of a wide variety of organs." The UCLA findings support the importance of gender-specific clinical trials. Most medication dosages for women have been based on clinical trials primarily conducted o...New tool tracks brain development in babies
...issue. Ischemia results in tissue changes that are visible with diffusion tensor imaging at least two to three hours before they can be seen on conventional MRI. The team then applied fiber tracking to construct a 3-D visualization of the brain's white matter tracts based on the diffusion tensor images. The ...New method for dating art prints and early books borrows know-how from genetic science
...of copperplate prints. The analyses reinforced the visible evidence that prints made from the same woodblock or copperplate were qualitatively different in later editions. Surprisingly, the analyses also revealed that the changes were usually clock-like on average, and therefore could be useful for calculati...Airborne mold spores increase kids' risk for multiple allergies
...ll and cement. Previous allergy studies focused on visible mold or total mold concentrations, not the identification of specific airborne fungal spores. The UC-led study showed that exposure to specific airborne fungal spores may increase allergic reactions and others could help reduce them. These findings ...UC Davis researchers report new molecule that targets leukemia and lymphoma cells
...es found and locked onto a tumor, the tumor became visible to a near-infrared scanner. LLP2A was identified using a combinatorial chemistry method Lam developed more than a decade ago. Known as the "one-bead-one-compound" method, Lam's technique allows scientists to synthesize millions of novel compounds in ...Seeing beyond the gray areas: New tool uncovers the importance of the brain's white matter
...erve fibers. Until now, white matter has been less visible because its structures are missed by magnetic resonance imaging (MRI) and other techniques. Now, because DTI has the ability to measure and model white matter tracts in the human brain, researchers believe there is new potential to discover the rol...Just-right PET/CT imaging for patients of all sizes
... detection of small lesions, some of which are not visible in a conventional reconstruction without TOF information, he explained. Research needs to continue, said Surti. "Our data indicate that more robust measures are needed to fully quantify the gains in imaging quality and to better define the relation...Colorful, rare-patterned male guppies have survival advantage in the wild
...ting, because guppies are highly polymorphic for a visible trait and they are easy to work with in field experiments. Researchers conducted 34 separate manipulations across 19 replicate pools in three streams over four years. They collected guppies from two tributaries of the Quare River and the main branch ...Satellite images obtained by AAAS program provide strong evidence of Zimbabwe repression
...eventive intervention. For example, he said, fires visible from government satellites may be able to signal that a campaign of repression is beginning. Bromley said that other scholars are trying to assemble and analyze a range of data from past conflicts--demographic and economic data, drought and other wea...Salk research suggests the existence of specialized neurons that distinguish swagger from sway
...l cortex are finely tuned to certain attributes of visible objects such as the color red, a certain shape or objects moving in a specific direction. These specialized neurons reveal their existence through a telltale effect called adaptation. For example, if you stare at a red patch and then look at a neutra...'Dead zone' summer killed billions of ocean state mussels
...s devastated. If the magnitude of this die-off was visible from the surface, there would've been public alarm." Altieri conducted the surveys with Jon Witman, a marine ecologist and an associate professor in the Department of Ecology and Evolutionary Biology. In a report on their research, published in Ecolo...Sea coral's trick helps scientists tag proteins
... to create a tiny fluorescent tag that responds to visible light. The two-color tag should help researchers f... when the tags are zapped with an intense pulse of visible blue light. The dramatic color change "makes it possible to precisely label an object, such as a cel...Molecule by molecule, new assay shows real-time gene activity
... membrane, where each attaches firmly. The clearly visible flash from each Tsr-Venus molecule -- which when viewed across a population of cells looks somewhat akin to a sea of cellular paparazzi -- serves as an indication of that single protein molecule's production. "Dr. Xie's experiments are the first to o...UCR researchers design chip that can improve citrus varieties
...on the chip. The locations of the bound RNA have a visible signal because of the tag, rather like bright and dim pixels on a computer screen. Analysis of which pieces of DNA on the chip have signals indicates which genes are expressed in the tissue. The chip is the first commercial citrus microarray and all...