Tag: "wanted" at biology news

Gene vaccine for Alzheimer's disease shows promising results

...r Biomedical Inventions and internal medicine. "We wanted to try a DNA-based genetic vaccine instead to see if we could enhance the immune response." Although prior studies of amyloid protein vaccination had shown some slowing in the plaque buildup, negative side effects also occurred in a handful of patien...

UCSD bioinformatics researcher studies tumor genome architectures with career award

..."Towards the end of my Ph.D. studies," he said, "I wanted to do something more applied, and bioinformatics was an exciting area." Raphael was awarded an Alfred P. Sloan Fellowship in 2002 because, he says, "the Foundation recognized the need for quantitative Ph.D.'s to work in biology." The 30-year-old res...

Potent anticancer drug increases function of axons in mouse model of neurodegeneration

...ojanowski. "We're working on that too, but we also wanted to find a drug that replaces the clumped tau in sick neurons." Microtubule-binding drugs derived from plants (taxol) and other biological organisms such as sponges (discodermolides) have been used as anti-cancer drugs because they prevent cells from ...

Immune system contributes to evolution of a new fluorescent protein

...all the genes they need," he said. "What we really wanted was an organism with cells that could rapidly produce mutations and target them to one specific gene," said Tsien. "To our surprise, that organism is us." SHM produces mutant genes at roughly a million times the rate of mutation elsewhere in the geno...

Don't count on vitamin C to boost your exercise performance

...effect, "we used sedentary older people because we wanted the highest level of oxidative stress as possible. But they were still healthy," Bell noted, and some earlier studies had "suggested that antioxidant administration may only prove to be beneficial for populations with elevated baseline oxidative stre...

Anti-seizure drugs slow aging in worms

...ofessor of molecular biology and pharmacology. "We wanted to look in an unbiased way at available compounds to see if any of them happened to have anti-aging activity." The researchers grew the roundworm C. elegans in the presence of the 19 drugs and found that an anticonvulsant, ethosuximide, extended the ...

Protein adiponectin appears protective against heart disease

...resistance to heart disease in type 1 diabetes, we wanted to evaluate whether adiponectin levels in these individuals might be predictive of future cardiac events." Adiponectin has been closely linked with insulin resistance, a known risk factor for heart disease. Adiponectin is one of the most abundant cir...

DNA molecules used to assemble nanoparticles

... of dendrimer clusters are in the works. "If you wanted to make a therapeutic that targeted five drugs to five different cells, it would be 25 synthesis steps the traditional way," Baker said. At two to three months per synthesis, and a significant loss of yield for each step, that approach just wouldn't ...

How do cells travel through our bodies?

...nd colleagues Christine Gurniak and Emerald Perlas wanted to know if it played a role in cell migration in the mouse. One stunning example of where the movement of a small group of cells is crucial occurs during the formation of an animal embryo. As the brain and head begin to take shape, a group of cells m...

Parents' attitudes to sperm donation still some concerns about being open

...ess to avoid accidental discovery and because they wanted to be honest. Almost half also said they believed ...was less inclined toward openness, and the parents wanted to remain consistent even if their own views had changed. Couples who had been together longer may a...

Chemists create 'Superbowl' molecule; May lead to better health

...and show more promise for wider applications." "I wanted a name for our compounds which acknowledged this and recognized their larger size and shape," says Sherburn. "'Superbowl' was perfect since it conjures up for me at least the image of a sports stadium, which the molecules are similar to in shape." ...

'Man the Hunter' theory is debunked in new book

...orate this key fossil evidence," Sussman says. "We wanted evidence, not just theory. We thoroughly examined literature available on the skulls, bones, footprints and on environmental evidence, both of our hominid ancestors and the predators that coexisted with them." Since the process of human evolution is...

Study finds direct association between cardiovascular disease and periodontal bacteria

...acteria tend to be dominant in dental plaque. "We wanted to know during the baseline examination of the participants whether it was true that the greater the proportion of so-called 'bad' bacteria in the mouth, the higher the likelihood of a thickened carotid artery," added Papapanou, whose laboratory perf...

Study methods, strains of Pfiesteria are both critical in determining organism's toxicity

...r a toxic strain is present." The researchers also wanted to test whether Pfiesteria can produce toxin without help from bacteria and as is known for other toxic algae whether bacteria enhance Pfiesteria's toxicity. Burkholder and her colleagues found that some strains of Pfiesteria were able to make toxi...

Study shows naturally occurring proteins protect against rapid tumor growth

...rs from developing into large malignant tumors. We wanted to better understand the important guards and checkpoints that our bodies possess." To test the hypothesis that angiogenesis inhibitor molecules were responsible for reining in tumor growth, Kalluri and his colleagues studied the proteins tumstatin, ...

Open microfluidic and nanofluidic systems

...er constraint applies to all length scales: if one wanted to build a robot which walks over water, for instance, a human-like robot is a bad idea while a spider-like robot is a much better choice....

ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors

...r attractiveness). As he studied these aspects, he wanted to understand more about what makes the colors of the birds possible, and then focused on "deconstructing the color into its component parts." McGraw said an interesting aspect of the five polyenal lipochromes that provide the red in parrots, is tha...

Brain region learns to anticipate risk, provides early warnings. suggests new study in Science

...he likelihood of making an error," Brown said. "We wanted to see if the cingulate would become more active even in situations where no conflict is presented and no errors are made, but the potential for error is still higher than normal" Methodolgy To test their hypothesis, Brown and Braver developed an e...

EU researchers in US want more contact with Europe

...n, over 90% of the 2000 respondents said that they wanted closer research links with Europe. The European Commission has therefore agreed to develop a networking and information tool called ERA-Link, which will be operational by the end of the year. ERA-Link will give European researchers working in the US ...

Scientists will discuss remarkable advances in whale research at the annual meeting of AAAS

...other mitochondrial gene called cytochrome b. ''We wanted to see if cytochrome b-a different gene with much nicer mutational characteristics than D loop-was going to give us the same answer,'' Palumbi says. ''Amazingly, we got the same estimate no matter which gene we used: The historic population of the An...

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(Date:10/17/2014)... Copenhagen have shown for the first time how bacteria ... patients, giving them the opportunity to get tremendous insights ... The study also discovered the bacterial growth in chronic ... or slowed down by the immune cells. The researchers ... helped "suffocate" the bacteria, forcing the bacteria to switch ...
(Date:10/16/2014)... on the human body. Battles are won, lost ... cancer, this stalemate—known as tumor dormancy—can last up ... phenomena that is poorly understood. , A ... Salvatore Torquato, a Professor of Chemistry at Princeton ... dormancy and the switch to a malignant state. ...
(Date:10/16/2014)... new synthesis of recent research findings to inform their ... two states. , The Ecology and Management of ... Synthesis of the Relevant Biophysical Science and Implications for ... the U.S. Forest Service,s Pacific Northwest Research Station, is ... a synthesis of the large body of scientific information ...
Breaking Biology News(10 mins):Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2Modeling tumor dormancy 2New report synthesizes best available science on management of moist mixed-conifer forests 2
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