Other highlights in the November 3 JNCI
...ith melphalan alone. They state that these results warrant further evaluation in a clinical setting. Contact: Timo L. M. ten Hagen, Daniel den Hoed Cancer Center, t.l.m.tenhagen@erasmusmc.nl Also in the November 3 JNCI: Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunot...Sick Kids researchers confirm that cancer stem cells initiate and grow brain tumours
...e new insight into patient prognosis that may then warrant individual tailoring of therapy." Dr. Dirks' laboratory was able to regrow an exact replica of patients' brain tumours in a mouse from the isolated cancer stem cells, or brain tumour initiating cells. They were then able to study the growth of the hu...The Cochrane Library Newsletter, 2005, Issue 1
... outcome, but the research wasn't strong enough to warrant alkalinisation as a standard therapy. "Further research into alkalinisation should be a priority, particularly to see whether sodium bicarbonate can help, because this chemical showed promising outcomes in early research, is cheap, wide...Highlights of the February Journal of the American Dietetic Association
...is beneficial effect becomes significant enough to warrant a general intake recommendation," say the researchers. The Journal of the American Dietetic Association is the official research publication of the American Dietetic Association and is the premier peer-reviewed journal in the field of nutrition and ...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...same. In fact, there are striking differences that warrant more investigation." The team included Roded Sharan, a computer scientist currently at the Tel-Aviv University in Israel; Tanja Kuhn and Peter Uetz, researchers at the Institute of Genetics in Karlsruhe, Germany; Ideker, Silpa Suthram, Ryan M. Kelley...Most older people with mild cognitive impairment have AD or cerebral vascular disease
...erformance on these tests was not severe enough to warrant a diagnosis of dementia. After death, the investigators measured the amount of Alzheimer's disease pathology and cerebral infarcts (strokes) through brain autopsy. Of the 37 individuals with MCI, more than half (23) met pathologic criteria for Alzhe...Beyond lithium for bipolar disorder
...der." They concluded that "the data presented here warrant further investigation of PACAP signaling in the brain and of the orphan receptor GPR88 as potential new targets in bipolar disorder." Philip E. Brandish, Ming Su, Daniel J. Holder, Paul Hodor, John Szumiloski, Robert R. Kleinhanz, Jaime E. Forbes, Mo...Science, AAAS select two for new minority internship
...e their editor that science is important enough to warrant more coverage." Which is exactly what Ornelas, a graduating senior, plans to do upon the completion of her Science internship. She said that her community newspaper's coverage of science tends to be untimely and doesn't delve deeply enough into the...AIUM to honor ultrasound pioneers at the 2005 AIUM 50th Anniversary convention
...utions to the development of diagnostic ultrasound warrant special merit. The 2005 Honorary Fellow Award will be presented to Michel Claudon, MD. The Honorary Fellow Award recognizes nonmembers who have contributed significantly to the field of ultrasound. Dr. Claudon will receive a complimentary lifetime ...DuPont announces additional $25 million funding for DuPont MIT alliance
...IT. "The successes and experiences of the Alliance warrant our continued funding," Connelly said. "In 2000, we asked MIT scientists to give us their best ideas on science that could enhance our everyday lives. The response and resulting research has led to significant scientific achievements. These first ...Racehorses, asthmatics, meatpackers may have similar etiology of airway disturbances
...proinflammatory cytokine expression. "These issues warrant further investigation, for which the equine model is ideally suited," the study notes. Some other "next steps" include: Looking at viral immunity in these cold-air scenarios, including "challenging" horses to see if blocking short-term inflammatio...Study is first to show side-stream smoking is as damaging to IVF success as being a smoker
...rmatory study, the findings from our study already warrant a warning to women to reduce or, if possible, prevent exposure to cigarette smoking, especially if they are trying to conceive," he said. The researchers plan to undertake a prospective study if funding for a research proposal under review is forthco...Discovery offers promising lead in prostate cancer diagnosis
...rived ETS factor (PDEF). "These novel observations warrant further studies looking into the functional effects of ERG overexpression in model systems of prostate cancer. It is likely that additional prostate cancer-relevant gene alterations also will be discovered by the microgenomics approach used in this s...National Academies news: DOE should consider enhancing cleanup and stabilization
... little residual waste or if special circumstances warrant closure, the committee said. It added that revising the closure schedule for tanks with insoluble wastes does not need to affect previously agreed-upon milestones for final closing of the tanks. In fact, if new technologies become available, they m...Study in Royal Society journal on possiblity of human organ regeneration
...o of the resulting populations are small enough to warrant special conservation consideration as a result of this fragmentation. Contact: Dr MF Proctor, Biological Sciences, University of Alberta, PO Box 920, KASLO, BRITISH COLUMBIA, V0G 1M0, Canada Molecular evolution of the sheep prion protein gene by Dr...To stem disease, keep cats indoors, stop feeding strays, scientist urges
...nion that the current evidence is strong enough to warrant an assumption of validity." Toxoplasma can infect most warm-blooded animals, as well as humans and birds. Domestic cats and some wild cats are the only animals that can transmit the parasite by shedding the organism in feces. Other animals become inf...ECCO 13 explores issues in cancer patient management
...ced levels of anxiety and depression sufficient to warrant further evaluation and management. High levels of depression, beyond their detrimental effects on global quality of life, may also hamper treatment decision-making and have been found to impede recovery and increase mortality. Despite worldwide recog...Genetic analysis of glioblastoma brain tumors can aid in treatment decisions, study shows
...c makeup often fail to show enough of an effect to warrant FDA approval for a drug because only a subset of patients respond well to the treatment. The researchers are now planning prospective clinical trials to determine whether selecting treatment based on each tumor's genetic activity can lead to better p...Langerhans cells regulate immune reactions in the skin
... Most such challenges are not dangerous and do not warrant an immune response." Langerhans cells may function generally to prevent excessive responses in the skin. "Failure of this mechanism could result in chronic inflammatory skin conditions like lupus and psoriasis, said Shlomchik. "This is the new theory...Patient outcomes linked to biomarker levels by quantitative technology
...ssociated withimmunohistochemistry. These findings warrant review by pathologists inquestioning the validity of current practices and before the data frompredictive biomarker studies is formally integrated into practice and patienttreatment."...