Australian-based research team finds the malaria parasite's 'housebreaking tool'
...e the red blood cells of its human victims. When a weak point is found, the intrusion proceeds. Scientists have known about the parasite's housebreaking habit for a decade, but just how it breaks in to blood cells has been unknown. Now, an international team of scientists, led by WEHI's Professor Alan C...Improving the potential of cancer vaccines
...cific immune responses, but such responses are too weak and transient to eradicate tumor cells." The answer lies in a group of cells called CD4+ regulatory T cells (Treg for short). These cells have the ability to suppress the body's natural immune response. If they are depleted, autoimmune diseases will ...New look at DNA hints at origin of ultraviolet damage
...hrough. "Even though paired bases are connected by weak chemical bonds, it's the interactions that take place without chemical bonds the interactions between stacked bases that are much more important for dissipating UV energy," Kohler said. The Nature paper builds on work from five years ago, when the ...Jonathan Baell wins Biota Award for Medicinal Chemistry
... effect of Khellinone is detectable but also quite weak certainly far too weak in its natural state to prevent myelin destruction. Dr Baell and his collaborators in Australia and ...How do you spell recognition? C-O-R-E-C-E-P-T-O-R
...ther part of the MHC molecule in a specific -- but weak -- interaction. Because of the specificity, CD8 is able to bind to MHC regardless of which antigen the MHC displays, and because the reaction is weak, CD8 and MHC can easily associate, dissociate, reassociate, and deassociate as the surfaces of a T c...Don Quixote's home shows way to future Earth Observation missions
...udy photosynthetic activity but the signal is very weak compared to direct sunlight. This campaign is the first time that large-scale outdoor measurements have been successfully carried out. Vegetation fluorescence represents a direct measurement of vegetation's ability to absorb atmospheric carbon diox...Sleeping beauty plays a significant role in identifying cancer genes
... be a major leap forward in understanding cancer's weak points and thus lead to better treatments." According to Largaespada, "About 300 human cancer-related genes have thus far been reported in the scientific literature. Most of those identified are involved in cancers of the blood system. So, there are......localization to the synovium (or joint lining) and weak localization to cartilage and bone. In addition, strong Wnt-7b expression most frequently correlated with areas of high inflammation. The authors also examined whether inflammatory cytokines were produced in primary cartilage and synovial cells fr...FSU meteorologists' work may lead to better tracking of hurricanes
...ethods do. The early spin of a tropical cyclone is weak and sometimes covered by clouds, and not easily detected by satellites that provide pictures of clouds. The ozone data gives scientists a "look beyond the clouds." Ozone is all around the world and in the upper and lower atmosphere. Ozone in the uppe...University of Chicago study overturns conventional theory in evolution
...icates strong selection; conversely, a high ratio, weak selection. Some genes have a ratio of 0, which means protein changes are not accepted. It is, in a sense, "perfect." For a pseudogene a stretch of DNA sequence that resembles a gene but has no function its Ka/Ks ratio is approximately 1.0, which me...Study: Plants use dual defense system to fight pathogens
...ogenic attackers. "The PAMP path induces a fairly weak immune response," Mackey said. "Even so, there is growing evidence that suggests these kinds of responses are extremely important in restricting the growth of many pathogens." The other pathway uses disease-resistant proteins, or R-proteins, which c...Super predators and mass extinctions; extreme NMR; and the world's smallest solenoids
...ing an NMR system that makes use of the relatively weak magnetic field of the Earth, rather than fields fr...niques that rely only on the Earth's natural, very weak magnetic field. Previous researchers have shown that the Earth's field is adequate for performing NM...New opportunities from old chemistry in surface science, say Purdue chemists
...termittent hold on the surface, and the relatively weak chemical bond makes them less attractive for applications that require environmentally durable coatings." Wei's team found that converting amines into DTCs empower them with an ability to grasp gold surfaces with a strength that thiols do not possess...Cure for common cold will need to wiggle to work, scientists say
... viruses. Their flexibility allows them to reach a weak spot in the viral shell." Post carried out the study with Purdue colleague Zhigang Zhou, a postdoctoral researcher in the Department of Medicinal Chemistry and Molecular Pharmacology, and Yumin Li, who performed the work as a Purdue postdoctoral rese...News tips: NASA presentations at Annual 2005 Joint Assembly Meeting
...dy). The study region was dominated by a series of weak frontal systems that mixed aged pollution with stratospheric ozone in the middle troposphere and analysis suggests that meteorological conditions led to reduced levels of ozone during summer 2004. Time/Location: Tuesday, May 24 at 9:30 a.m. EDT (8:3...Researchers find genetic link to cerebral hemorrhage and porencephaly
...n of cells with accumulated mutant protein and the weak basement membrane around blood vessels predisposes to hemorrhage. To determine whether humans with porencephaly also have COL4A1 mutations, the researchers studied two families with a history of the disease and found the mutations. Control families h...PNAS highlights for the week of May 16 - 20
...tor had parallel veins with alternating strong and weak adherence properties. Adhesion dropped when the separation between the veins bonding the aspartate became so small that the leucine segments no longer fit between the veins. The researchers suggest this precise spatial control of amino acids on inorg...Atmosphere may cleanse itself better than previously thought
...light, making them easily detectable. However, the weak absorptions in the lower region of the ultraviolet... the molecular systems of interest frequently have weak spectral features there, so they're tough to see," said Francisco, who contributed the study's compu...Season of birth influences age of menopause, say Italian researchers
...ribute to the development of defective embryos and weak adults. "Our present data seem to indicate that women born in autumn develop better during their prenatal life and are born with a higher number of oocytes than women born in spring," said Dr Cagnacci. "An alternative explanation may be that early mo...Scientists reveal how disease bacterium survives inside immune system cell
...phil response to A. phagocytophilum with that of a weak strain of S. aureus. Using microarray technology that allowed them to compare about 14,000 different human genes, the researchers discovered how the response to A. phagocytophilum deviates from that of S. aureus, and thus permits the HGA agent to su...