Biased reporting found in cancer prognostic studies
...een TP53 status and head and neck cancer mortality weakened as they expanded their analyses from the 18 published and indexed studies alone to include the 13 studies with published data only. The association vanished after they added in the unpublished data from 11 studies. Additionally, 72% of 18 published...Australian discovery of adult stem cells in the uterus could restore your pelvic floor & more
... can happen to younger women. The pelvic floor is weakened during pregnancy and childbirth and as a woman ages the strength of these muscles can deteriorate further," Dr Rosamilia explained. "At present we use surgery to repair prolapsed uterus, which is a form of hernia," she said. However, in almost 30% of...Elderly mice yield clues to the process of growing old
...earing and vision impairment, loss of muscle mass, weakened bones and fewer circulating red blood cells. Mitochondria are structures within cells that provide energy for cells to move, divide, contract and secrete products vital for the health of organisms. "We think that the key to what is happening in agin...Secret sex life of killer fungus?
...ially life-threatening infections in patients with weakened immune systems. It is also a major cause of respiratory allergy, and it is implicated in asthma as well. The fungus has always been thought to lack the ability to reproduce sexually, but new discoveries by a multinational group of scientists indicate...UCSD researchers boost white blood cells' ability to kill bacteria
...esistant bacteria or those affecting patients with weakened immune systems due to chronic disease, cancer chemotherapy or AIDS," said Nizet. "Rather than designing drugs to target the bacteria, medications that promote HIF-1 activity could be used to boost the bacterial killing ability of white blood cells a...Grand Challenges in Global Health initiative funds Yale project
...or HIV and a range of other diseases are made from weakened versions of the infectious agent. These cannot be studied in human trials unless researchers are confident that they are safe. "A big need in the world of vaccine development is the ability to predict whether vaccines for humans are safe and effecti...ASU's Curtiss awarded $14.8M from Gates Foundation to develop new pneumonia vaccine for newborns
...accine with a safe, low-cost additive derived from weakened Salmonella bacteria, which early studies suggest can enhance a vaccine's ability to stimulate a potent immune response. Curtiss' team will also work to design the vaccine so that it can be given orally; oral delivery is less dependent on sterile con...Fragment of yellow fever virus may hold key to safer vaccine
... the potential side effects from variations of the weakened virus strain now grown in fertilized chicken eggs.......ately after drinking soda (the brush will harm the weakened enamel) When brushing, brush in a circular motion (horizontal brushing can wear away at the weakened enamel) If you have dry mouth, try to avoid carbonated beverages....Chemical that triggers hibernation may protect muscles
...nist naloxone was used, the results showed that it weakened the effects of HWP, suggesting that HWP works in part through some type of action on opioid receptors. The researchers conclude that "pharmacological preconditioning of skeletal muscle to reduce necrosis [tissue death] associated with hypoxia/reperfu...Live vaccines more effective against horse herpes virus
...minary research indicates that vaccines containing weakened live viruses, called modified live vaccines (MLV),...nces in which a previous MLV that was incompletely weakened caused neurological disease symptoms after it was administered. The more widely used type of vaccine...Researchers find genetic link to cerebral hemorrhage and porencephaly
...is also variable, the researchers suggest that the weakened blood vessels in the brain could be damaged by str... COL4A1 genes, actions to reduce the stress on the weakened cerebral blood vessels could reduce the neurological damage. For example, Cesarean delivery of at-ri...Turning viruses into allies against cancer
...and Destroys Liver Cancer Cells: Abstract LB-297 A weakened measles virus, modified with a protein that normally takes up iodine in the thyroid gland, is being studied to treat human liver cancer cells grafted in an animal model. Scientists at the Mayo Clinic in Rochester, Minn., reported that the engineered ...New strategies to reduce hospital-acquired infections
...t health threat to patients, especially those with weakened immune systems. By all accounts the prevalence of infections caused by some of the most potentially lethal waterborne microbes, such as legionella and pseudomonas, are underestimated." He explained that waterborne microbes- -bacteria, viruses, fungi ......r architecture, with irregularly sized vessels and weakened vessel walls. Dr. Weiss explains that "These findings, coupled with complementary reports from our group that cancer cells themselves use MT1-MMP to regulate their proliferative and metastatic properties, suggest that therapeutics directed against th...Earth's services in peril, report concludes
...d to improve the lives of billions, they have also weakened nature's ability to deliver other key services such as purification of air and water, protection from disasters and the provision of medicines." Only four of the ecosystem services examined by the assessment were found to be increasing in their abi...Discovery may lead to better Candidiasis drug
...ongue and throat. It affects primarily people with weakened immune systems caused by antibiotics, chemotherapy or by diseases such as AIDS. Thrush also affects many denture wearers. The condition can be treated with antifungal medication in otherwise healthy people, said Edgerton, but it is difficult to tr...Blocking cell signaling can stymie viral infections, study shows
...infection, it poses potential risks to people with weakened immune systems either as a result of disease or treatment for cancer or with autoimmune disorders such as the skin condition eczema. "The advantage of targeting signaling pathways is that cells, and the structures that send and receive signals, are...Essential oils could help to stamp out MRSA
...tment for cancer and leukaemia are often left with weakened immune systems which makes them vulnerable to infection from MRSA.The National Audit Office estimates that infections such as MRSA kill 5,000 people each year and hospital-acquired infections cost the NHS around 1 billion a year....Potent anticancer drug increases function of axons in mouse model of neurodegeneration
...ell loss with subsequent dementia, parkinsonism or weakened motor skills in peripheral muscles, and later muscle atrophy. The protein tau, like Paxceed (or other natural products such as taxanes and discodermolides), is required to stabilize the microtubule. "Think of tau as the cross-tie of the microtubule ...