Preclinical study links gene to brain aneurysm formation
...eurysms. An aneurysm occurs when a blood vessel weakens and stretches, forming a bulge in the vessel wall that can rupture and hemorrhage. Intracranial arterial aneurysms are bulges that develop in the arteries that carry blood to the brain. Previous studies have shown that variants of the NOS-3 gene ar...Study suggests other causes for childhood brain aneurysms
...lopment. An aneurysm occurs when a blood vessel weakens and stretches, forming a bulge in the vessel wall that can rupture and hemorrhage. Intracranial arterial aneurysmsuncommon in pediatric patientsare bulges that develop in the arteries that carry blood to the brain. In addition, Abruzzo reports that...Bigger horns equal better genes
... which is the idea that, because natural selection weakens with age, genetic mutations have effects that accumulate over time. Therefore, differences in genetic quality become more apparent as an organism ages. Coltman noted that his study, which incorporated genetic samples from more than 150 ibex, took ......ays are currently small. However, if the infection weakens and pigs dont get infected with HEV until they are older, more pigs will still be carrying the virus when they reach the slaughterhouse. HEV, which is found worldwide, can potentially cause acute hepatitis in humans. So monitoring infection rates ...New treatments have major impact on heart failure rates
...e a progressive disorder when damage to the heart weakens the cardiovascular system and poor heart muscle function causes fluid in the lungs. This is the first time such findings relating to heart failure, a chronic condition often requiring specialised nursing care in the community, have been made. In ......d, which gives them a negative charge. This charge weakens the interactions between the hydrophobic, lipophilic regions of the proteins, which are necessary for oligomerization. "Our insights form a foundation for the establishment of an effective spinning process for the production genetically engineered s...Problem forgetting may be a natural mechanism gone awry
...er, then memory can be disrupted by something that weakens those connections. When we see someone we know or perhaps even ourselves becoming more forgetful, we now know that this is not an inevitable process, Foster said. Further, as we begin to understand the mechanisms of memory, it becomes possible to p...Researcher to study astronaut bone loss for space biology agency
...n bone in the weightlessness of space dramatically weakens bone," says Long. "The ability of humans to conduct prolonged missions to the moon and Mars will require that the structural integrity of the skeleton be maintained." Astronauts who spend weeks or months in the weightless environment of space a st...Scientists find potential 'off-switch' for HIV virus
...o try to keep the virus asleep if possible." HIV weakens the body's immune system by invading CD4+ T cells, which in essence serve as the metaphorical generals in the body's defense system against illness. When an HIV virus particle invades a T cell, most often it converts the cell into a factory for makin...Scientists crack rhino horn riddle
...tists report. The softer outer portion of the horn weakens with sun exposure and is worn into its distinctive shape through horn clashing and by being rubbed on the ground and vegetation. The structure of the rhino horns is similar to a pencil's tough lead core and weaker wood periphery, which allows the hor...Diversity promotes cooperation among microbes
... don't produce the polymer. The presence of cheats weakens the biofilm, imperiling its survival by causing it to sink. In the new work, the researchers studied the effect of short-term evolution of diversity within the biofilm on the success of cooperation. The researchers found that within biofilms, diver...Study shows how cancer drug aids anti-cancer virus
...motherapeutic drug called cyclophosphamide briefly weakens those immune cells, giving the anti-cancer virus an opportunity to spread more completely through the tumor and kill more cancer cells. Specifically, the drug slows the activity of immune cells called natural killer (NK) cells and macrophages, whic...Microscopic passengers to hitch ride on space shuttle
...n. Prior studies have indicated that spaceflight weakens the human immune system and that some microbes become more virulent when grown under conditions that simulate spaceflight, thus increasing the risk of astronauts becoming sick during flight. Whatever the mission or its duration, microbes are present ...Epilepsy drug eases symptoms of inherited disorder that weakens muscles
...t sufferers with a genetic disorder that seriously weakens muscles. Scientists at Washington University Schoo...val motor neuron (SMN) protein. This progressively weakens the muscles, leading to difficulty in walking, eating, clearing the air passageway, and other essent...The molecular mechanism of a diabetes vaccine revealed
...oimmune disease. This double action of the peptide weakens the damaging activities of the immune response further. The scientists also showed that in order to activate this response, p277 must be bound to the receptor TLR-2, which is found on the cell walls of the regulatory T cells. "These findings are impo...New step toward treatment for Duchenne muscular dystrophy
...ir by their early teens. The disease progressively weakens all muscles, notably respiratory muscles, compromising life expectancy. Most sufferers die between the ages of 20 and 30. Today, there is no treatment--only rehabilitation, surgical procedures and prednisone to enhance patients' quality of life. New ...Blood pressure medication may revolutionize treatment of Marfan syndrome
...cations of Marfan syndrome, a genetic disease that weakens the structural meshwork of blood vessels. People who have Marfan syndrome have a high risk of developing aortic aneurysm, which can lead to rupture of the heart's largest artery, causing sudden death. In studies published in the April 7, 2006, issue ...The rising tide of ocean plagues: How humans are changing the dynamics of disease
...rn, promote the growth of bacteria, which kills or weakens the coral. This leaves more room for the algae to take over, smothering corals and increasing sugar production, starting the cycle over again and rapidly changing reefs to fields of algae. In healthy systems, some of this algal growth would be kept ...A cancer promoting protein shows up in an unexpected place in the cell
...be added to K-Ras. This "phosphorylation" process weakens the electrostatic bonds that anchor the protein, allowing it to dislodge from the plasma membrane. Based on prior work, the researchers expected that the dislodged K-Ras would attach to the membrane of organelles in the cell, such as the endop...Common food preservative might provide treatment for cystic fibrosis
...ways of cystic fibrosis patients and significantly weakens them. The new study suggests, however, that a mutation--known as mucA--in the organism also represents a fatal flaw that could help physicians clear the characteristic "goop" from the lungs of advanced cystic fibrosis patients. The reason for opti...