UCLA scientists uncork fountain of youth for HIV-fighting cells
...merase's power over telomeres may provide a potent weapon in helping the AIDS patient's exhausted immune system defend itself against HIV. The researchers extracted immune cells from the blood of HIV-infected persons and tested what would happen if telomerase remained permanently switched on in the cell. ...A new mechanism of regulating RNA degradation
...me player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and clinicians who want to take control of gene expression in cells to create therapies to treat disease. While cells have a variety of ways to control gene expression, the trick for p...VCU research shows erectile dysfunction drug reduces death of heart cells in heart attack model
...spase 3, the protein considered to be the ultimate weapon in cell suicide. "This research has established a strong basis for the design of future studies targeted toward investigating the clinical effects of sildenafil on survival of heart muscle following a major heart attack," said Rakesh C. Kukreja, Ph.D......a time when the threat of smallpox as a biological weapon is high. TITLE: Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction AUTHOR CONTACT: Ellis L. Reinherz Dana-Farber Cancer Institute, Boston, Massachusetts, USA. Phone: 617-632-3412; ...Blocking cell signaling can stymie viral infections, study shows
...Smallpox has been identified as a potential terror weapon because, with the suspension of universal vaccination against the virus in the 1970s, most Americans are thought to have little immunity to the often lethal disease. The NIAID grant supports research into the basic workings of the immune system, with...Stopping smallpox in its tracks: A new anti-viral approach
...a time when the threat of smallpox as a biological weapon is high....Could microbes solve Russia's chemical weapons conundrum?
...products caused by the destruction of the chemical weapon mustard, write Russian researchers in Journal of Chemical Technology and Biotechnology ( http://www.interscience.wiley.com/jctb ) this month. At 40,000 tonnes, Russia houses the world's largest stockpile of chemical warfare agents (CWAs). The country...Highlights of chemical society national meeting in San Diego, March 13-17
...e, and Food Safety.) Antidepressants may be novel weapon against SARS While the deadly SARS virus (Severe Acute Respiratory Syndrome) appears to be under control for now, health officials are concerned about its possible resurgence. Researchers in Taiwan say that they have discovered a potential way to k...Scientists find viruses can't stick to sea bugs in the dark
...l," says Ying Jia. Cyanophages may be an important weapon against problematic algal blooms. On hot, sunny days algae can cause massive, toxic blooms, poisoning huge areas of the sea with their waste products and killing fish, sea mammals such as whales, dolphins and seals, and even humans. Control of these ......em would identify a truck backfiring rather than a weapon discharging. The Chicago and Los Angeles County police departments are testing the system to help fight crime in areas that are low on beat officers. Safety Dynamics received a Small Business Innovation Research Phase I award from the Navy in 2004 an...Researchers find gene that may be at root of potato blight
...y victim. "This avirulence gene is kind of like a weapon that triggers a metal detector," said Sophien Kamoun, a study co-author and an associate professor of plant pathology at Ohio State University 's Ohio Agricultural Research and Development Center in Wooster . "If you take a gun through the metal det...Gram-negative bacteria shoot their way into cells
...nic plague, and whooping cough all deploy the same weapon to infect the body. A molecular "syringe" sticks out of the bacteria, pokes a hole in a nearby cell, and squirts in venomous proteins that hijack the cell's machinery. For the first time, Howard Hughes Medical Institute researchers have captured a d...Tips from the Journals of the American Society for Microbiology
...ax poses a deadly threat as a potential biological weapon placing added emphasis on the need for a safe and effective vaccine. The vaccine currently available doesn't protect against the bacilli and may be hazardous to its host when used immediately after exposure. In the study researchers infected two g...New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
The immune system is a complex and powerful weapon that provides protection against bacteria and viruses that, if left unchecked, would wreak havoc throughout the human body. The ability of the immune system to recognize the body's own tissues is essential, but sometimes the immune system loses the ...Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT
...iscredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate. The compound, tricirbine, was tested at various cancer centers from 1982 to 1996 and found to inhibit some cancers, but researchers failed to det...Researchers find potential Celebrex target in lung cancer
...t for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center. Researchers found that PGE2, which is produced normally by epithelial cells but at very high levels in lung cancer and other malignancies, up-regulates the activi...Elevated temperature enhances success of viral cancer therapy
...new research suggests that fever might be a useful weapon in the fight as well. The study, published in the July issue of Cancer Cell, demonstrates that tumor cells are even more sensitive to viral therapy after they have been incubated at an elevated temperature. The findings could have a significant impac...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...ng an intrinsic property of nanotubes to develop a weapon that kills cancer." Trojan horse To assure that only diseased cells were destroyed in the experiment, the scientists had to find a way to selectively deliver carbon nanotubes into cancer cells and not into healthy ones. Dai and his co-workers achie...Weapon performance determines mating success in the collared lizard
...otypic variation can include that of body size and weapon morphology, as well as of weapon function and performance. In a study published in the September issue of The American Naturalist, A.......ic that could affect millions worldwide. The best weapon is containment, said Neil Ferguson, a Howard Hughes Medical Institute international research scholar and professor of mathematical biology at Imperial College London. Ferguson headed a study whose findings are being published online by the journal N...