Scientists harness diptheria toxin and interleukin 2 to help the immune system attack melanoma
...oma nine or twelve micrograms per kilogram of body weight daily for four days, every three weeks for four cycles. The two patients on the lower dose had newly detectable tumours and tumour growth after two cycles. However, the five patients on the higher dose experienced significant regression of several ...Beetle feet stick to their promises
...ts. It has already been shown to perform in higher weight categories: the artificial adhesive fibers on the soles of a 120 gram robot helped it to climb a vertical glass wall (Daltorio et al. 2005). In their current research, the scientists are trying to improve the adhesion by refining the structures eve...Reduced body temperature extends lifespan in study from the Scripps Research Institute
...rimental and control mice ate the same amount. The weight of the female experimental and control mice did not differ significantly. However, experimental male mice weighed about 10 percent more than the control group, most likely reflecting the reduced energy required to maintain a lower core body temperatu...Joslin Diabetes Center study examines insulin pump therapy in adolescents
... glucose monitoring and growth parameters (height, weight and body-mass index). These data also were monitored at the time of discontinuation for patients who stopped using the pump. Examining the data associated with success and failure, the researchers observed several significant differences between th...Other highlights in the November 1 JNCI
...d with paclitaxel, EA5 substantially reduced tumor weight and helped mice survive for longer periods of time. Contacts: Scott Merville, 713-792-0661, sdmervil@mdanderson.org Immunohistochemical Assay Predicts Clinical Trial Results for Breast Cancer Patients Better than Older Assays A recent ...MIT engineers probe spiders' polymer art
...hey then use their hind legs as well as their body weight and gravity to elongate the gel into a fine thread. Kojic, who first practiced on silkworms, learned how to extract a microscopic amount of the gel-like solution from the spider's silk-producing major ampullate gland. The researchers used devices ...Data show treatment with Remicade reduced hospitalizations for ulcerative colitis patients by half
... breath, swelling of your ankles or feet or sudden weight gain). Reactivation of hepatitis B virus has been reported in patients who are carriers of this virus and are taking TNF blockers, such as REMICADE. Some of these cases have been fatal. Tell your doctor if you know or think you may be a carrier of ...Orexigen reports positive phase II results for Excalia Combination-Therapy to treat obesity
...tended to provide and sustain clinically important weight loss, demonstrated significant weight loss in a six month, double-blind, phase IIa clinical study. The magnitude of weight reduction excee...Metabolic disorder underlies Huntington's disease
...o explain other symptoms of the disease, including weight loss, and could point to new avenues for therapy, according to the researchers. "Huntington's has been thought of primarily as a neurological disease," said Albert R. La Spada of the University of Washington, Seattle. "Our findings underscore the fa...Grape seed extract halts cell cycle, checking growth of colorectal tumors in mice
... treated mice were reduced by 44 percent and tumor weight by percent, compared to control animals. No toxic side effects were observed in treated mice, despite the high doses. Similar to the cell culture studies, Cip1/p21 protein levels increased in tumors in mice treated with grape seed extract, Agarwal ...USC groups present at Neuroscience 2006
...LS, they maintained strong muscles and normal body weight almost until the end, the study reports. In additi... results indicate that myostatin deletion can slow weight loss, muscle wasting and motoneuron death as well as improve motor performance and life span [female...Childhood cancer survivors may have low birth weight children
...problems, including early deliveries and low birth weight children, according to a study in the October 19 Journal of the National Cancer Institute. New therapies for childhood cancer patients have increased survival, but many scientists are concerned about the long-term effects of the treatments, par...Brain protein improves stroke symptoms in rats, even when injected after 3 days
...njected with a single dose of G-CSF at 60g/kg body weight four hours after the stroke. The researchers demon...In this model, the rats were injected 10 g/kg body weight of G-CSF, starting 24 or 72 hours after the stroke, for a period of ten days. Rats treated with G-CS...LIAI scientists make major advance in the fight against chronic virus infections
...veloped a normal antiviral immune response, gained weight and returned to a healthy state." Von Herrath noted that their studies showed that the treatment worked best when given immediately after infection. "The later you give it after the infection, the lesser the efficacy," he said. Von Herrath said th...Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing
...que also allows for production of higher molecular weight chains, thereby extending the range of accessible ...d. For example, chemists could grow high molecular weight polymers with precise control, providing even larger templates for nanoscale carbon structures used ...JCI table of contents: Oct. 5, 2006
... copies of the gene Rai1 corrects the reduced body weight and learning defects observed in a mouse model of dup(17)(p11.2p11.2). This study, which indicates that duplication of a single gene -- Rai1 -- can lead to a complex disorder in mice, not only has implications for individuals with dup(17)(p11.2p11.2)...Fruit juice intake among preschool children not associated with weight
...on between 100 percent fruit juice consumption and weight status among preschool children ages 2 to 5. I...n this study is a number calculated from a child's weight and height and is based on special criteria established for children by the Centers for Disease Cont...New technique boosts size of proteins that can be analyzed
...tein and of the individual pieces. By matching the weight of the whole protein and its pieces with those of ...xample, if a section of a protein has an increased weight of 16, researchers can tell that the protein has been oxidized within that section, which means that...New study finds chocolate chip cookies lower cholesterol
...most likely to raise risk for heart disease. Body weight did not change and there were no changes in HDL (good) cholesterol. According to the Center for Disease Control, a 10 percent decrease in total cholesterol levels may result in an estimated 30 percent reduction in the incidence of coronary heart dise...Promising antiobesity drug fails to produce clinically meaningful weight loss
...ty therapy failed to produce clinically meaningful weight loss in obese people in a long-term clinical trial...as found to be well tolerated and to induce modest weight loss in obese individuals. The amount of weight loss and proportion of receptors bound by the drug r...