GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science
...ensive structure-function investigations on a much wider range of therapeutic protein targets," Dr. Gerngross commented....Researchers identify key step in cocaine-induced heart enlargement, sudden death
...rt. The USF researchers' findings may also have wider implications for other forms of heart enlargement caused by chronic disease. "The biomolecular pathway that we've identified likely also plays an important role in heart hypertrophy due to hypertension, heart attacks and heart failure," Dr. Henning s...Research partnership to protect the Coorong
... The Collaboration Fund enables the skills of the wider Australian research community to be applied to the major national challenges targeted by CSIRO's Flagship Initiative. Led by Dr Mike Geddes of the University of Adelaide, the multidisciplinary research team will carry out a detailed study of the ec...Major new osteoporosis study to recruit people in Orkney
...sults of the study will still be applicable to the wider population, as have results from studies in Iceland. The new study will piggyback on an existing research project in Orkney (ORCADES) which has involved 1, 400 volunteers and is looking at genetic influences on cardiovascular disease. Two researc...New study provides a clearer picture of breast-cancer gene mutations in American women
... prevalence and predictors of these mutations in a wider spectrum of the general population, including understudied groups like African-Americans and older women, is important and long overdue," said epidemiologist Malone, a member of the Hutchinson Center's Public Health Sciences Division. In a study of m...New findings offer more complete view of breast cancer gene mutations in US population
...elihood of carrying BRCA1 and BRCA2 mutations in a wider spectrum of women," said one of the study's lead investigators, Elaine Ostrander, Ph.D., chief of the Cancer Genetics Branch in the National Human Genome Research Institute's Division of Intramural Research. Dr. Ostrander was previously head of the g...Insect 'noses' the key to cybernose collaboration
...ing, designed to facilitate the involvement of the wider Australian research community in addressing the cr...gship Collaboration Fund enables the skills of the wider Australian research community to be applied to the major national challenges targeted by CSIRO's Fla...Biodiversity, Ecosystem Processes and Human Health
... global N cycle largely escapes the attention of a wider audience. Alan Townsend (University of Colorado) will present the talk "Brown clouds, green water, and red herrings: Human health effects of an altered nitrogen cycle," focusing on environmentally-harbored diseases. There is growing evidence that N...ACRUS broadens contraceptive spray strategy
...has paved the way for Acrux to apply MDTS to a far wider range of contraceptive hormones, which in turn makes our technology more attractive topotential global partners," said Richard Treagus, Acrux CEO. Following the successful completion of Phase 1 clinical trials with Nestorone MDTS, Acrux has moved...Invasive species alter habitat to their benefit
... that is larger than either parent and tolerates a wider range of environmental conditions. In the marshes she studied, Farrer found that hybrids were more common than native cattails. She also noted that the areas of each marsh with lots of hybrid cattails had higher nutrient levels and heavier mats of...Shorter tuberculosis therapies could lead to substantial reductions in cases and deaths
...scenarios in which new regimens are accompanied by wider case detection, which might arise if shorter therapies can free up scarce financial and human resources, simplify program administration and patient monitoring and prompt more people to seek care. Applying the model to the South-East Asia region,...Gene discovery may shed light on kidney disease
...2 mutations and the Notch signaling pathway in the wider population of patients with kidney disorders. She also will investigate liver involvement in Alagille syndrome under the Rare Diseases Clinical Research Network, recently established by the National Institutes of Health. "Part of the rationale for ...Marine 'dead zone' off Oregon is spreading
...in 2003, 2004 and 2005. The 2006 "dead zone" has a wider north-south extent. Some crabbers in the central Washington coast reported all dead crabs in pots at depths of about 45-90 feet, north of the Moclips River. Large numbers of dead Dungeness crab have been reported on the beach as far north as Kalaloch...Improving livestock health, trade and human livelihoods in Africa
...ember states and regional communities to address a wider range of policy issues." ...Human behavior changes the number of strains of infectious diseases
...icable, but stress that their conclusions may have wider relevance. "There are implications for all sorts of other infections too," Eames continues. "Just think of the behavioral differences between village and city life: one with quiet streets and few new faces, and the other with thousands of hurrying ...Pine plantations may be one culprit in increasing carbon dioxide levels
...for instance, a natural pine stand typically has a wider variety of plant and tree species growing in it than a plantation does. To encourage owners of hardwood and natural pine forests to hold on to their stands, the researchers suggest that existing conservation programs and private transactions for ca...Titans of biodiversity science call for united, authoritative voice to inform decision-makers
...making internationally. And they called upon the wider scientific community and stakeholders to lend acti...nventions, non-governmental organizations, and the wider public. The four-year process that led to the Millennium Ecosystem Assessment (MEA) was a first at...Direct link established between tropical tree and insect diversity
...h greater numbers of tree species should support a wider variety of leaf-eating insects than do less diverse forests, but no one had ever done the experiment to rule out the major alternative explanation: that insect species in the tropics eat the leaves of a smaller number of host trees (are more host spe...Yellowstone ecosystem may lose key migrant
... passes, and moving through bottlenecks now barely wider than a football field due to recent residential development. Increased petroleum extraction could further impact the migration route. Six of eight antelope migration corridors in and out of the Yellowstone ecosystem have already been lost. "It's a...Genetics behind developmental brain disorders may play a wider role with congenital diseases
...that genetic variants of these proteins may play a wider role with inherited human diseases. Study results appeared in the June issue of the American Journal of Human Genetics. The findings give vital clues to the basis of some developmental disorders and make early diagnosis possible for diseases such a...