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Jan Lwe awarded 2007 EMBO Gold Medal

...ected for the award in recognition of his landmark work elucidating the structure and function of proteins... Institute for Cell and Molecular Biosciences. His work highlights the complexity and sophistication of bacterial cells, and how they remain wonderful subje...

MIT model could predict cells' response to drugs

... execute the behavorial functions." The pathways work via a series of signals in which proteins, known as kinases, activate other cell machinery to achieve a specific result, e.g., expression of certain genes, or actions of cytoskeletal proteins. While the same stimuli can produce diverse responses in d...

Researchers find pathway that controls cell size and division

...idnt know it. Knowing when to divide Further work indicated that the mutation perturbed FtsZ ring fo...ble to maintain proper distribution of DNA. This work is also something of a cautionary tale about the limitations of genome sequencing. More and more oft...

Nature's weapon against nerve agents

...li firm Braintact, and follows earlier unpublished work with rats which showed the enzyme successfully pro...iting and killing nearby nerve cells. In related work published earlier this year, by Vivian Teichberg at the Weizmann Institute of Science and researcher...

Risk genes for multiple sclerosis uncovered

...sk factors ever published. In an effort to see the work extended, we are now committed to making the entire data set available to MS researchers worldwide. This is just the beginning, says Hauser. This international collaboration is currently planning even larger and more detailed explorations of the g...

Nottingham biosciences million pound injection

...he Wellcome Trust Award is recognition of the hard work and creativity of a large team of scientists who have worked at the University of Nottingham and within Regentec over the past five years. They are pioneers in terms of their science, but also in ensuring that the expertise and knowledge honed in a...

St. Jude study solves mystery of mammalian ears

...the ability to discriminate among frequencies. The work also highlights the importance of basic hearing re...dies into the causes of deafness. A report on this work appears in the advanced online issue of Proceedings of the National Academy of Science. Our disco...

New target for HIV/AIDS drugs and vaccine discovered

...hor of the article, The findings described in this work may have several implications for AIDS treatment: the understanding of Nef function, mechanism of action, and cellular partners might aid the discovery of suitable drugs able to block the activity of this smart protein. Quaranta added, An exciting po...

$9M grant awarded to University of Cincinnati for bipolar disorder research

...oping in the brain that impact how treatments will work during different times in the illness. Strakows... ultimate goal of being able to predict what might work best for each individual. Bipolar disorder is a serious mental illness that causes dramatic shifts...

Surprising new species of light-harvesting bacterium discovered in Yellowstone

... am really grateful to Dave Ward for the chance to work with him and his students in the park and to visit Montana frequently. Our collaboration is a great example of how science really becomes exciting when scientists from different disciplines interact."...

Report recommends off-site disposal of secondary waste

...ions. Decontamination solutions are used to wash work areas and decontaminate workers prior to removal of their suits. They are analyzed for contaminants, treated if necessary, and disposed of either on- or off-site. The committee found that disposal of these spent solutions does not present a signifi...

More fish oil, less vegetable oil, better for your health

...mith says. By better understanding how prostanoids work at the cellular level, we hope to find new ways to regulate inflammation and create better anti-inflammatory drugs....

When off-target is right on

...uld evolution choose such an inexact system" The work of and Dr. Tsvi Tlusty and research student Yonatan Savir of the Weizmann Institutes Physics of Complex Systems Department suggests a possible answer. A simple biophysical model they developed indicates that in picking out the target molecule from a ...

Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process

...the high-energy costs of the reaction. Helicases work hand in hand with polymerases in replication, so it makes sense that the helicase would work on one base pair at a time, said Institute for Genomic Biology professor Sua Myong, lead author on t...

Boston Univeristy bioengineers devise 'dimmer swith' to regulate gene expression in mammal cells

...cian would to build an electric light switch. Much work in the field to date uses bacteria or yeast, but the Boston University team used more complex mammalian cells, from hamsters and mice. The switch has several new design features that extend possible applications into areas from basic research to gene...

Presence of wolves allows aspen recovery in Yellowstone

...searchers say they believe there are two forces at work both the lower populations of elk, and their changed behavior due to fear of wolves but its difficult to determine exactly which force is the most significant. Of note, they say, is that elk populations now are actually higher than they were in t...

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...nd proteins by the T cell. But the Carnegie Mellon work suggests that FP-23 plays another, equally important function reducing the free energy of curved fusion intermediates. These fleeting shapes arise and disappear as HIV enters a T cell. Normally, a cell membrane resists bending. Scientists can quan...

Gene-transcription machinery seen poised for action, held in check until needed

...machinery needed to transcribe that gene to put to work the information it encodes. Now, a new study led by researchers at The Wistar Institute suggests that the gene-transcription machinery, once in place, can remain poised for action but held in check until a triggering signal sends it on its way down t...

Springer launches Theoretical Ecology

...ly come of age, as the importance and influence of work in this area continues to grow. The time is ripe for a journal in this area, and Theoretical Ecology is designed to fill this need. The audience will include all ecologists and other scientists as well....

Study points to new way to predict death risk from torn aorta

...ed with stent grafts -- and that this research and work by other researchers around the world lends further weight to the model proposed from the new data. Still, he says, only prospective research and other validation efforts will be able to tell if the false-lumen model is accurate. The NEJM paper is...

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(Date:11/24/2009)...tute (LRI) today named 12 new grant recipients for...e innovative work across a broad spectrum of lupus... novelty, and potential to drive scientific discov...plex disease of systemic lupus. , The 2009 grant... across the nation and include interdisciplinary a...
(Date:11/24/2009)...of a remarkable class of ring-shaped protein motor...nce Berkeley National Laboratory (Berkeley Lab) us...mline at the Advanced Light Source (ALS). These pr... and replication, and are vital to the survival of...s, such as the human papillomavirus, which has bee...
(Date:11/24/2009)...ood is a matter of debate. A high-profile study a ...rcent of their carbon from trees and leaves, evide...and aquatic ecosystems. , But new research from ...ely to be true. Algae provide a much richer diet f...rch published this week in the Proceedings of the...
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