New therapy for specific form of leukemia
...onnected to another gene. Due to this fusion, ABL1 works non-stop − stimulating cell growth unremittingly. This process leads to an uncontrolled growth of immature white blood cells and thus to T-ALL. With these findings, the researchers have revealed a new mechanism for the formation of active cance...Stanford cooling tool may improve performance of athletes, soldiers
...an Biology and Environmental Biology. The device works by creating a local subatmospheric pressure environment, Grahn says. "We stick the hand in a rigid chamber with an airtight seal around the wrist, and then we draw a bit of the air out of the chamber," he explains. "This causes blood to be pulled int...Putting physiology into the Nobel Prize: 2004 marks 100th anniversary of Pavlov's award
...ard, to quote the citation: "in recognition of his works on the physiology of digestion with which works he transformed and broadened substantially the knowledge in this field." Pavlov made many contribut...Low dose radiation evades cancer cells' protective 'radar'
...t from suppression of a protein, called ATM* which works like a radar to detect DNA damage and begin repair...ction by the radiation. While the low-dose regimen works in cultured cells, it has not proved successful in humans. This has lead to effort by Hopkins scient...Interactive health information system to detect Japanese encephalitis in Asia
...TH is an international nonprofit organization that works to create sustainable, culturally relevant solutions, enabling communities worldwide to break longstanding cycles of poor health.The goal of the project is to trackand ultimately reducethe incidence of Japanese encephalitis through improved surveilla...Emory chemists develop bacteria that may help decaffeinate coffee
...rofessor of chemistry. "What we do know is that it works very slowly. Ideally, we would like to speed it up a bit so that we could create coffee plants that are low in caffeine. That's where the bacteria come in. They now need the breakdown product of the enzyme (theophylline) for survival, but they can't ...Protein protecting brain from toxins also blocks some chemotherapy from reaching tumors
...ependent transporter. The study showed that Mrp4 works at two levels: by binding to topotecan and transporting it away from the brain Mrp4 restricts the drug's penetration into the brain from the bloodstream; and it protects brain cells from accumulating toxic levels of topotecan molecules that do escape...UF scientists have bionanotechnology recipe to find elusive bacteria
... at a tiny, molecular-sized scale. Nanotechnology works with objects that are on the order of 1 to 100 nanometers; a nanometer is one-billionth of a meter, about the size of several atoms. When combined with molecular biology, the possible applications of this nano-frontier are widespread and sound like t...Study in Royal Society journals presents evidence for inherited factors in homosexuality
...is and Dr C Tsakmakis There are some experimental works which provide compelling arguments for the presence of length scale effects in the constitutive laws governing the response of plastically deformable materials. These experiments are referred to specimens with lateral dimensions of a few micrometer. ...INEEL uses extremophile bacteria to ease bleaching's environmental cost
... alkaline environments," Thompson says. "But if it works in industry, that's the most important thing right now." The INEEL team is discussing collaborations for industrial development with major enzyme manufacturers. After isolating and producing large quantities of the enzyme in the lab, scientists can u...Technology award presented to Weizmann Institute scientist
...echnology and society of the future. Shapiro, who works in both the Computer Science and Applied Mathematics and the Biological Chemistry departments of the Weizmann Institute, has been recognized for the creation of biomolecular computing devices. These devices are made entirely of DNA and other biologi...Research into the sense of touch in worms wins Eppendorf/Science Prize
...search using worms to learn how the sense of touch works on a molecular level. The Eppendorf and Science Prize in Neurobiology recognizes outstanding neurobiological research by a young scientist, as described in a 1,000 word essay based on research performed within the last three years. The grand prize wi...Perceptual decision-making hub pinpointed in human brain
...titute of Mental Health (NIMH) have discovered. It works by gauging the strength of competing signals from lower brain areas specialized for recognizing different objects, report Drs. Hauke Heekeren, Leslie Ungerleider, and colleagues, in the October 14, 2004 Nature. Although earlier studies in monkeys ha...Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...uired to discover whether the mechanism discovered works in the same way in human breast cancer. The authors of the study emphasise the importance of a moderate consumption of fats although some of them, such as blue fish and olive oils, have been shown to be beneficial to health. These oils are common ele...Zebrafish may offer researchers powerful new tool for studying innate immunity
...ary Litman, PhD, Hines professor of pediatrics who works at the Children's Research Institute at the University of South Florida and All Children's Hospital. "They may be related to receptors in humans involved in natural killer cell function." Natural killer cells sense and kill malignant cells and cells...Medical geneticists elected to Institute of Medicine
...a group called Genetic Resources on the Web, which works with organizations sponsoring genetics-related Web sites to ensure they contain high-quality information. Prior to joining NHGRI in 1999, Dr. Guttmacher directed the Vermont Regional Genetics Center at the University of Vermont in Burlington, ...Gene for Joubert syndrom with excessive brain folds discovered by UCSD researchers and Harvard team
...ained that "if we can understand how the AHI1 gene works and how its dysfunction leads to disordered brain development, it can tell us something about the biology underlying a common disorder like autism." Also important are the implications for genetic testing, Gleeson added. "We receive...Babies born after surgery on eggs
...contain their own DNA, and Tzeng thinks the method works by replacing those with damaged DNA. In eggs, mitochondria have only one copy of this DNA, making them vulnerable to damage as women age. In contrast, mitochondria in the granulosa cells have around five copies. Because the method involves adding a ...Molecule that helps DNA replicate may make good target for cancer therapy
...ork with chicken blood cells to confirm that Mcm10 works the same way in vertebrates as in yeast.......discovery of this gene and further study of how it works could open up new avenues of research for preventing or delaying the onset of the disease. In research, the study of rare familial forms of a disease has often led to major insights into the pathogenesis of more common forms. The finding was publish...