New gene regulation mechanism discovered
... stimulated by various stress conditions including wound healing and viral infection. "That told us that when cells are stressed, maybe the atypical messenger RNA is released from the nucleus, exported to the cytoplasm, and translated into protein, thus circumventing the time-consuming process of producing...ITHACA, N.Y. -- How does a wound in certain plants like roses and grapevines develo... common soil bacterium that is able to "smell" the wound and speed up the infection process. Cornell University microbiologist Steve Winans says that the pat...Scientists unpick genetics of first 15 minutes of life
...ists found that the pro-nucleus in ssame mutant is wound into a tight ball that could not interact with its female counterpart, the egg pro-nucleus. This showed that there was a problem with the re-packaging process in the ssame mutant. The researchers looked at the genetic makeup of the ssame mutant and i...Polymer gel can block toxic leakage problem in gene therapy
...he form of a polymer compound already employed for wound healing and for drug and gene delivery. After being mixed with a gene-bearing virus, this compound -- called poloxamer 407 -- undergoes a temporary phase change as its stiffens from a liquid to a gel state when warmed to body temperature, that study ......r the cellular motility that governs nerve growth, wound healing and cancer metastasis. Their study appears...focused on migrating fibroblast cells important in wound healing. To move towards a wound, these cells manufacture the protein actin, which polymerizes into ...Post-Katrina: Lead in disturbed soil may pose heightened health risk
...e known human pathogen that can cause diarrhea and wound infections. This is the first time that Aeromonas has been detected in the Katrina floodwaters, Presley says. Animal tissues sampled, including dead snakes and an alligator, also contained multiple metals and pesticides, but these levels were genera...Cancer scientists call for a large-scale human epigenome project
...ular "clips" that hold the six feet of DNA tightly wound inside each cell - are modified by methylation, but also by the addition of chemical entities containing acetic acid, phosphorus, and a number of other species. The complex nature of epigenetic modifications constitutes a challenge to the development...Argonne researchers contribute 1000th structure
... behavior during tissue genesis and repair such as wound healing. These functions are mediated by its interaction with a proteins and proteoglycans in the extracellular environment and at the cell surface. The research was published in Structure (2006 Jan. 14 (1): 33-42), and is a collaboration between th...UCSD study finds anthrax toxins also harmful to fruit flies
...pted by LF treatment is similar mechanistically to wound healing, which is mediated by the same signaling pathway in humans. The EF toxin is also lethal when applied to fly larvae and can cause severe malformation in the wings of adult fruit flies--an effect that can also be understood as an interruption o...Aging cells, aging body: Fresh evidence for a connection
...do and are associated with skin wrinkles, delayed wound healing, weakened immune system response and age-related diseases such as cancer. "There is good evidence that senescent cells are not benign," Sedivy said. "But until now, no one has been able to confirm that they exist in appreciable numbers in old...Heparin prepared synthetically could replace animal-derived drug
... regulate cell growth and may have applications in wound healing or cancer treatment, according to the researchers. The findings were reported Dec. 30, 2005, in the Journal of Biological Chemistry in a paper titled "Enzymatic redesigning of biological active heparan sulfate." The process also can be applie...Herbal supplements, a smoking gun in plastic surgery
...er, it can trigger immunosuppression, causing poor wound healing and infection. Glucosamine, often offered in conjunction with chondroitin, contains chemical elements that mimic human insulin, and may artificially cause hypoglycemia during surgery. Other common supplements taken by patients in the study t...The rising tide of ocean plagues: How humans are changing the dynamics of disease
...ations and you really don't want to expose an open wound to near shore water," says Dobson. "We should begin to worry deeply about the health of the oceans."...JCI table of contents, February 23, 2006
...ells, nerve cells, and blood cells, which enhances wound healing. However, the mechanisms responsible for r...gulation of bone marrowderived progenitor cells in wound repair and migration. The authors suggest that inhibiting this homing process could be useful in sup...Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
...ells, nerve cells, and blood cells, which enhances wound healing. However, the mechanisms responsible for ...gulation of bone marrowderived progenitor cells in wound repair and migration. The authors suggest that inhibiting this homing process could be useful in su...Manchester scientists create new bio-gel for 3D cell culture
...cur in the body and has potential applications for wound healing and tissue engineering. Cell scaffolds, kn...ffer us great potential for future applications in wound healing and regenerative medicine." Dr Ulijn and his collaborators have successfully cultured cartil...Wound monitor 'sniffs out' infections
... The funding will be used to create a non-invasive wound monitor to treat patients with severe burns, skin ...s of infection. When bacteria metabolises inside a wound molecules of that bacteria are emitted into the air. Current methods rely on medical staff taking sw...A new focus for the mechanism of nerve growth
... such as directed cell movement, cell division and wound closure. While skeletal myosins have been studied in detail, non-muscle myosins are just beginning to be understood and this work identifies a new role for them. The researchers, led by Paul Forscher , professor of molecular, cellular and developm...Getting ACL tears to heal themselves
...scopic approach that would squirt the gel into the wound via two small incisions in the knee. Her team is also trying to enhance the gel to speed the healing process. MORE: Until the 1970s, surgeons tried to repair ACL tears by sewing the ligament ends back together, but the sutures nearly always failed......und that patients who got a four-component vaccine wound up only being protected against one or two versions at most, due to immunodominance. Intrigued by these results, Deem and graduate student Hao Zhou developed a precise computer model of the immune system's biochemical scanning process to see if they ...