Tag: "yeast" at biology news
New textbook illuminates the close links between evolutionary and molecular biology
...jumping genes and RNA molecules, to populations of yeast
and E. coli reared in the laboratory, to dung flies, lizards, and deer in their natural habitats. Evolutionary biology underpins all our knowledge of the living world, write the authors. [It] is a synthesis of Darwinian natural selection and Men...
ESF EURYI award winner aims to stop cancer cells reading their own DNA
...r molecular insights, confirming her hypotheses in yeast
cells. Indeed the work with antitumor drugs is, as far as I know, the first experiment in which single-molecule experiments have resulted in a prediction for a cellular effect, said Dekker. ...
Evolution is driven by gene regulation
...ts for the difference between species at least in yeast
according to a report by Yale researchers in this...d to find that even the closely related species of yeast
had extensively differing patterns of regulation. In this study, the authors found the DNA binding...
Unknotting DNA clue to cancer syndrome
...st, SGS1. They found that when SGS1 was defective, yeast
chromosomes became more promiscuous in combining w...ng the chromosome arms to form a crossover. Both yeast
and human cells contain two copies of each chromosome, one from each parent. During the cell divisio...
Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
...olecular Cell," two molecular biologists have used yeast
artificial chromosomes to prove the hypothesis. Th...d to the fragility. Freudenreich and Zhang used yeast
artificial chromosomes to test this idea because it allowed them to look at the region in a more det...
Researchers find pathway that controls cell size and division
...gg for example. In single-celled organisms such as yeast
and bacteria nutrient availability is the primary determinant of cell size. In animal cells size is controlled in large part by a molecule that senses the blood sugar dependent hormone insulin. Petra Levin, Ph.D., Assistant Professor of Biology at...
New research shows vaginal bacteria vary among healthy women, need customized treatment
...health problems, including bacterial vaginosis and yeast
infections, and those problems send them in droves...hed light on why some women have recurrent vaginal yeast
infections, while others have never had one partly explain differences in susceptibility to infecti...
Maynard Olson receives $500,000 Gruber Genetics Prize
... genomes into manageable pieces, applied it to the yeast
genome, and made the human genome project a possib...500,000. When he assembled his physical map of the yeast
genome, Maynard developed a new way to piece together the puzzle. He allowed us to mechanize, comput...
Tomorrow's green nanofactories
... Dr. Belchers research with viruses, proteins and yeast
offers hope for new, ground-breaking solutions to the worlds energy problems. It holds out the prospect of using nanotechnology in a variety of ways, ranging from improving the efficiency of production, storage, and transmission of energy to overcomi...
Tiny tweezers and yeast help St. Jude show how cancer drug works
...nanotechnology called magnetic tweezers as well as yeast
cells, investigators showed that a camptothecin dr... kill cancer cells, and then tested that theory in yeast
cells. Their conclusionthat accumulation of DNA supercoiling kills the cellsprovides a novel model f...
NIEHS researchers identify enzyme critical in DNA replication
...ays in replicating DNA in higher organisms such as yeast
and perhaps even humans. The study places us one step closer to understanding the origins of genome instability that underlie certain environmental diseases in humans, said NIEHS Director David A. Schwartz, M.D. NIEHS is part of the National Ins...
Prion propagates in foreign host
...s. A key difference between the two is that the yeast
prion proteins are rich in the amino acids glutami...st. "We showed that the fusion formed a prion in yeast
and it was infectious," Liebman said. "It's the first time a prion from one organism has been propag...
Doing nature one better: Expanding the genetic code in living mammalian cells
...octoral researcher in Wangs laboratory. Relying on yeast
to do the dirty job of finding a synthetase that r...elped them to overcome the second challenge. Using yeast
for the selection process and then transferring the enzyme for use in mammalian cells may sound like...
TU Delft tracks the influence of a cancer inhibitor on a single DNA molecule
...SA) the mechanism could also be observed in living yeast
St. Jude study yields secrets of chromosome movement
...e Children's Research Hospital have used the lowly yeast
to gain insights into how a dividing human cell en...St. Jude team studied combinations of molecules in yeast
called the RITS and RDRC complexes, which together with an enzyme called Clr4 (Suv39 in humans), est...
Largest synthetic gene ever built offers insights into anti-malarial drug resistance
...that we have these genes expressed in a convenient yeast
system, we can work to understand the molecular ba...form − into one that could be "read" by yeast. The yeast
are then able to produce the PfMDR1 protein, in its proper sequence, from this synthetic gene. They ...
In search of the biological significance of modular structures in protein networks
...y, now suggests that the structural modules in the yeast
protein-protein interaction network may have originated as an evolutionary byproduct without much biological significance. There is little evidence that the previously observed structural modules correspond in any way to functional units. It seems ...
Engineered protein effective against Staphylococcus aureus toxin
...expressed the engineered protein on the surface of yeast
cells (using a process they helped develop, called "yeast display") and generated mutations meant to increase the protein's ability to bind SEB. After several rounds of mutagenesis and screening, graduate student Rebecca A. Buonpane developed a solub...
Latent memory of cells comes to life
...on-existent capacities suddenly to appear. Special yeast
cells for example, can abruptly change from being ...experiment molecular biologists used a mutant of a yeast
cell which was bi-stable, in that it could become either of a single sex or hermaphrodite. The exper...
Hives ferment a yeasty brew, attract beetle pest
... The beetles are also aided in their invasion by a yeast
that naturally occurs on pollen and produces, as a... researchers report. Complicating the issue is the yeast
that grows in the hives. The researchers found that this yeast
only produced IPA when it grew on pol...
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