Tag: "animal" at medical news

Shark-Liver Substance May Slow Growth Of Brain Tumors

Results of Johns Hopkins animal studies show that a natural shark substance nearly stops the growth of new blood vessels that nourish solid brain tumors. The results suggest that the substance, squalamine, named for the shark genus Squalus, may find a role with chemotherapy, radiat...

Scientists Produce New Anti-Malarial Compound

...w todevelop more potent compounds, leading to more animal testing. Finding new anti-malarial agents is important because Plasmodiumparasites are becoming increasingly resistant to chloroquine andother traditional drugs used to treat malaria patients. The anti-malarial drug artemisinin, extracted from the pl...

Fertilization Protein Structure To AID in Leukemia Treatment

...e California sea snail, Aplysia californica , an animal used by biologists to study the process of fertili...oins with an egg are often the same throughout the animal kingdom, including in humans. One of the first events is that a flood of calcium ions is released a...

Laser Shown Effective In Patients Who Are Not Candidates For Bypass Surgery Or Angioplasty

...rowth into thenew channels. At Duke, we are using animal models to better understandexactly why this occurs. It appears that the new growth is somehow relatedto the inflammatory response to the creation of the channels. Once we figureout exactly how and why it works, we can then make it work better." ...

Common Carbohydrates May Prove To Be Substitute For Dietary Fiber

...are finding a growinglist of benefits to human and animal digestive systems from certain formsof indigestibl...charides, said George C. Fahey Jr., a professor of animal sciencesand of nutrition at the University of Illinois. "Oligosaccharides may prove to be a replace...

Study Injects New Interest In How Vaccines Work

...rm of aluminum found in small amounts in human and animal tissue -- Hem was able to extrapolate how much of ...us who specializes in mineralogy, Mark Suckow, lab animal veterinarian, Anita Rudy, pharmacokineticist from Indiana University Medical School, and Euphemie Da...

New Approach To Multidrug Resistance

...ell as side effects. The researchers are now doing animal studies to determine the most effectivecombination of drugs, and human clinical trials to determine the effectivenessof this approach in various natural cancers. The Dartmouth team includes Michael Ihnat, Jean Lariviere, Amy Warren, Nicole LaRonde, ...

Psychiatric Symptoms May Signal Brain Damage From Diet Pills

...D., and colleagues, report on their review of 90 animal studies on serotonin neurotoxicity and primary pul...induce drowsiness. The study cautions that if the animal findings apply to humans, the brain damage "would be expected to occur in almost everyone taking a d...

Antioxidant-Enhancing Drug Partly Rescues Noise-Induced Hearing Loss

...nt study, which describes the action of R-PIAin an animal model, will be presented on Friday, Sept. 12, at the Inner EarBiology Meeting in Bari, Italy. Donald Henderson, Ph.D., UB professor of communicative disorders andsciences, said the action of R-PIA likely would be similar in the human ear. ...

Rats Receiving Ginkgo Biloba Learn Quicker, Live 20 Percent Longer Than Controls, UB Study Finds

...n age-related cognitive deficits, using rats as an animal model. "At a certain point in our analysis, ..., he noted, are a lack of agreement on appropriate animal models and their applicability to humans when memory and cognition are concerned, and the absence of...

Penn Researchers Create Drug To Help Target Attack On Cancerous Tumors

...rs demonstrating the safety and efficacy of EF5 in animal tumor models and says that EF5 has shown no toxicity in animal studies. In the trial, a second method of measuring hypoxia is also employed where a thin ne...

BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference

...otecting agents. BioNumerik presented preclinical animal study data showing that BNP7787 cancompletely protect against cisplatin-induced renal, emesis and bone marrowtoxicities and can increase cisplatin's antitumor activity. It also showed, forexample, complete tumor remissions increased from 13% (with a...

New Research In Battling Alzheimer's Impact On Memory

...ating into the insoluble plaque. Although no good animal modelexists for Alzheimer's disease, according to Donald F. Weaver, Ph.D.,researchers are currently testing their compounds in mice with amyloid-ladenspleens. After molecular modeling simulations and extensive structure-activityrelationship determin...

UB Plants "Seeds" By Investing In Research Projects; Researchers Leverage Investment 14 Times Over

...ew Program in Cognitive Neuroscience to develop an animal model of attention deficit disorder. The model will help Bender and Lock develop an understanding of what is occurring in the brains of affected children in order to find new ways to treat the disorder.Original UB investment: $19,600 o A $728,000 g...

Chemical Society's Highest Award Goes To Ronald Breslow

...o such chemotherapy agents are promising so far in animal trials withthe National Cancer Institute. Every kind of tissue needs to make enough new cells to replace old onesor to grow. Thus the body keeps an inventory of immature "templates" called stemcells. These juveniles can't function in digestio...

Emerging Pathogens And Safety Of Fresh Produce Key Issues Facing Food IndustryAnd Scientists

...erborne protist (one-celled organism withplant and animal characteristics) that affects fish and possibly human health,will also be discussed. Viruses and parasites may be transmitted to food viacontaminated water where seafood is harvested, drinking water, water used for irrigation, or water in the soil w...

Compound In Meat Prevents Diabetes, Study Suggests

...due; and Karen Houseknecht, assistant professor of animal sciences at Purdue and an adjunct assistant profes... possible. Meanwhile, Houseknecht plans additional animal studies to determine how CLA regulates glucose metabolism. "Our next step will be to see if the weig...

Mice Free Of Anxiety By A Deficient Stress Hormone Receptor--A Hint For A NewTherapeutic Regimen In The Treatment Of Depression And Anxiety

...ss hormone cortisol.Moreover, it has been shown in animal models, in patients with depression, andby molecular biological examinations that the negative feed back loop of the HPAaxis is altered and that cortisol is unable to suppress CRH secretion. Theelevated CRH level is probably responsible for the sympt...

Nitrosamines Play Important Role In Cancer Linked To Smoking

...cancer is formed by cancer-specific nitrosaminesin animal models, their fate in humans can be more fully determined, Hechtbelieves. This is the focus of his own research, to elucidate the factors whichinfluence cancer development upon exposure to carcinogens. Hecht also suggests that by understanding the w...

Brain Tumor Treatment In Multicenter Tests

...ave arisen from a variety of cancers.Evidence from animal studies suggest that the treatment is safe and effective.The researcher's own experience with a handful of individual cases has beenpositive. Says Ewend: "It allows for high local doses of chemotherapy with nosystemic toxicity." Candidates for t...

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