Tag: "discovery" at medical news
Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
... signaling the brain that the stomach is full -- a discovery
that could leadto a new class of drugs that bypass the leptin brain circuit and target the fat cell itself. Duke researchers say their study, reported today in the journal Nature,is the first to demonstrate how leptin initiates the burning of store...
Discovery Hints At Multitude Of New Targets For Drugs
...interaction with drugs or hormones. "The discovery
of such complexity in one receptor type is a phenomenon;the discovery
of two is a paradigm," said McDonnell. "It's likelythat these findings will extend to other receptor...
NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...ceptors are a superfamily of hundreds ofreceptors, discovery
of this unique messaging system has given research...iology? He answered the first question through his discovery
thatthe transcription of testis ACE in the mouse is initiated by a testis-specificpromoter located w...
Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...alf of the funds are designated fordrug/technology discovery
grants that will support research on identifiedreagents/technologies that warrant continued research via clinical studies. The remaining portion of the funds will support pre-clinicaland clinical trials of new compounds developed at Duke, or other in...
Chemists Closing In On Commercial Potential Of Alkanes
...h the University of California at Berkeley, ledthe discovery
of a group of organometallic complexes --compounds of metal atoms,such as iridium or rhodium, sandwiched between organic molecules with a uniqueproperty. Upon irradiation with ultraviolet light, these organometallics wereshown to generate a reaction...
"Powerful New Tool" For AIDS Is Reported In Science
...rug therapies (cocktails) and accelerated new drug discovery
State College, PA-- February 25, 1998 -- Science reported, in its 20 February 1998 issue, a novel AIDS directed technology developed by Dr. Marc Hellerstein of the University of California at Berkeley and the University of California at San Fran...
Researchers Identify Biochemically Distinct Pain Phenomena, Conclude Better Pain Relief At Lower Morphine Doses Is Possible
...ed by Allan Basbaum, PhD, now has made thestriking discovery
that -- biologically -- mild pain and more intense pain aredistinct and governed by different signaling molecules. Effective management ofintense pain should take these distinctions into account, Basbaum says. "Pain is not a single phenomeno...
BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference
... and mechanismbased approach to new pharmaceutical discovery
and development. Regarding BioNumerik's BNP7787 a...BioNumerik is particularly meaningful because the discovery
anddesign of both of these agents was supported by BioNumerik's mechanism basedcomputational studies...
Chemical Society's Highest Award Goes To Ronald Breslow
...ard is namedfor Joseph Priestley, who reported the discovery
of oxygen in 1774, and itsfirst recipient, in 1923, was Ira Remsen, the chemist credited with bringinglaboratory research to the American university. "What I do is make new molecules with interesting properties,"particularly in medicine, summ...
Identification Of Brain Areas Could Help Eliminate Side Effects Of Pain Medication
...alph Lydic, Ph.D., professor of anesthesia. "This discovery
means we have specifically targeted an area in th...pain control and anesthesia safety. He adds, "The discovery
of anesthesia is only about 150 years old, and it is important to remember that for no anesthetic ...
Wistar Scientist Awarded American Cancer Society Grant For Study Of Tumor
...egastroenteritis (rotavirus), and cytomegalovirus; discovery
of molecules likeinterleukin-12, which are helping the immune system fight bacteria, parasites,viruses and cancer; and location of genes that contribute to the development ofdiseases like breast, lung and prostate cancer. Wistar is a National Cancer...
Scientists Report Cancer Fighting Drug As Possible Treatment For Multiple
...s have madesignificant achievements, including the discovery
that DNA is the carrier ofgenetic information and the launching of the scientific field of modern cellbiology. The university has ties to 19 Nobel laureates, including the president,Torsten N. Wiesel, M.D., who received the prize in 1981. The univers...
Three INEEL Inventions Win International Recognition
...Malt-based Antimicrobial product resulted from the discovery
that malting ofcereal grains activates biological compounds that functions to protect the plantagainst disease caused by bacteria and fungi. These protective mechanisms occurnaturally during germination, which malting simulates. The Malt-based Antimi...
Lupus Foundation Of America Awards Summer Internship To Student Working At Wistar Institute
... gastroenteritis (rotavirus), and cytomegalovirus; discovery
ofmolecules like interleukin-12, which are helping the immune system fightbacteria, parasites, viruses and cancer; and location of genes that contributeto the development of diseases like breast, lung and prostate cancer. Wistar isa National Cancer ...
National Science Foundation Awards Knowledge And Distributed Intelligence Grants
...egy selection here involves inductive learning and discovery
processes. The here goal is to provide a rigorous treatment of the reasoning behavior of automated agents by using belief-revision logics to model belief-based learning.The long-term significance of the proposed research is the dissemination of auto...
BioNumerik Reports The Supercomputer Supported Discovery Of New, Non-Toxic Chemotherapy Protecting Agent
...he journalSeminars in Oncology which describes the discovery
and mechanism of action of anew non-toxic, second-... ofpatients. BioNumerik investigators began their discovery
efforts in this areawith the idea that if it were possible to safely increase the total dose or thed...
University Of Pittsburgh Chosen By NCI As One Of Three Pioneer Sites ForBiocombinatorial Chemistry Research
.... Biocombinatorial chemistry exploits the discovery
of genes and theirproteins, which serve as molecul...added Dr. Lazo. This new approach to drug discovery
combines university expertise ingenomics (the discovery
and classification of new genes), chemical d...
Discovery: Experiments Confirm Novel Eye Pigment Controls Circadian Rhythm
... "We are extremely excited about this fundamental discovery
because itappears to be so central to mental and physiologic functioning," Sancar said."Previously, it was assumed that the same pigment in the eye was responsible forvision and circadian synchronization, and now we know that's not true." Dis...
WFU And IntraVec To Develop Innovative Cancer And HIV Treatments
... IntraVec's HIV treatments will be based on Chen's discovery
of a methodfor genetically altering white blood cells (lymphocytes) to make them imperviousto entry by the HIV virus. During infection by HIV the lymphocytes -- the body'smain disease-fighters -- are taken over by the virus, which multiplies there,re...
Signal Pharmaceuticals Announces Positive Results In Preclinical Study Of Novel Drug Leads For Treatment Of Osteoporosis
....D. commented, "Signal's integratedtarget and drug discovery
capabilities allowed us to progress from leaddisco...r the treatment of osteoporosis. To expeditethe discovery
and validation of these drugs, Signal also developed a proprietaryin vitro human bone model system t...
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