Research offers hope of new treatments for liver damage
...ase in the numbers of patients with advanced liver fibrosis (scarring) and cirrhosis (end stage scarring of the liver). Currently, we have no effective treatment for liver cirrhosis which is associated with internal bleeding, liver failure and the development of primary liver cancer. There is a huge imperativ...Donor age has no affect on long-term liver transplant survival
...g term survival after liver transplant, as well as fibrosis in these patients. Led by Dimitrios N. Samonakis, of the Liver Transplantation and Hepatobiliary Unit of the Royal Free Hospital in London, the study examined 195 transplantations due to end stage cirrhosis related to hepatitis C that took place betw...Mountaineering doctors hike medicine to new heights with Xtreme Everest
...eart and lung conditions, "blue babies" and cystic fibrosis sufferers. The summiteers will also test a prototype closed-circuit breathing system. This type of circuit has only once previously - and unsuccessfully - been used by climbers attempting the summit. The equipment, adapted from firefighters' apparatu...Jefferson scientists uncover potential trigger of diabetic kidney disease
...d start the apoptosis pathway and ultimately cause fibrosis and progressive kidney failure as a result. We found almost all of the apoptotic cells had CD36 in them. If we block CD36 in cell culture, these proteins and free fatty acids don't cause apoptosis." Next, the researchers would like to develop a mouse...Trial reveals safer and simpler approach to treating children with cystic fibrosis
Treating chest infections in young cystic fibrosis patients with an antibiotic once instead of three ...sed for the management of patients who have cystic fibrosis and chronic chest infection with a bacterium called Pseudomonas aerginosa. Currently patients are gi...American Thoracic Society Journal news tips for February 2005 (first issue)
...e major transmissible pathogen that affects cystic fibrosis (CF) patients, Pseudomonas aeruginosa, by effectively segregating patients with transmissible disease during hospitalization at their dedicated CF facility. Researchers realized that despite their carefully designed center and strict hygiene rules, ...Animal study shows link between nicotine and atrial flutter
...) significantly increases the incidence of cardiac fibrosis in canine hearts. This reaction promotes a kind o...used a significant increase in atrial interstitial fibrosis (a two-fold increase in the left atrium and a 10-fold increase in the right atrium) in the myocardia...Sildenafil effectively treats enlarged hearts, mouse study shows
...tress for seven to 10 days, with hearts developing fibrosis and muscle growth by nearly 65 percent. After two weeks of therapy, fibrosis and muscle growth almost completely disappeared. In mice that did not have therapy, hearts continue...Research offers hope of new treatments for liver damage 'plague'
...ase in the numbers of patients with advanced liver fibrosis (scarring) and cirrhosis (end stage scarring of the liver). Currently, we have no effective treatment for liver cirrhosis which is associated with internal bleeding, liver failure and the development of primary liver cancer. There is a huge imperativ...New findings on patient safety at children's hospitals
... to a child's underlying condition, such as cystic fibrosis or a heart defect, not by a preventable incident or mistake. "This is the first time that the national patient safety indicators have been applied to children's hospitals specifically, and we find both encouraging news for patients and a chance to re...NIH action plan charts future challenges for liver disease research
...ailability of reliable and safe means of measuring fibrosis (tissue scarring) and cirrhosis (excessive scarring and destruction of liver structure) would improve management of liver disease and facilitate clinical research. Developing sensitive and specific means of screening individuals at high risk for e...Transplanted bone marrow cells reduce liver fibrosis in mice
...ells can reduce carbon tetrachloride-induced liver fibrosis in mice and significantly improve their survival r...iver fibrosis. The researchers first caused liver fibrosis in the mice by injecting them with carbon tetrachloride (CCI4) twice a week for four weeks. They the...Research with red tide toxin yields potential therapies for cystic fibrosis
...at may treat mucus build-up associated with cystic fibrosis and similar lung diseases. Preliminary studies sho...of drug therapies for those who suffer from cystic fibrosis and other lung disorders characterized by excessive mucus secretion," said Baden. Cystic fibrosis is...Serum caspase activity and liver fibrosis in patients with hepatitis C
... sensitive method to detect higher stages of liver fibrosis in chronic HCV infection," the researchers report....ed caspase activation more likely have progressive fibrosis and therefore should be monitored carefully....Studies demonstrate positive data in treatment of hepatitis C
... in 550 chronic hepatitis C patients with advanced fibrosis who had previously failed interferon-based therapies. A total of 59 patients reached a clinical verified endpoint: 39 in the colchicine group versus 20 in the peginterferon alfa-2b group (p=0.003). The annual clinical event rate was approximately f...News briefs from the journal Chest, October 2004
...resence of congenital conditions, including cystic fibrosis and respiratory distress syndrome. The study appears in the October issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. KIDS AND PARENTS NOT ACCURATELY MEASURING ASTHMA MEDICATION ...Attention to detail can make kids' hospital stays shorter, less costly & less frequent
...database. Nasr's team is doing the same for cystic fibrosis patients. Adult services are also using the acuity-adjusted APR-DRGs -- UMHS chief of clinical affairs Darrell Campbell notes that APR-DRGs adjusted for the U-M's unique patient population are helping guide improvements in care at the...Study finds lung transplants increase survival of cystic fibrosis patients by more than four years
...ion increases the survival of patients with cystic fibrosis by almost 4.5 years on average, according to a stu...lly the risks from lung transplantation for cystic fibrosis patients are quite high, but the risk drops over time, and it becomes worth the risk in the long run......laboratory test results to detect inflammation and fibrosis in the liver. "We're pleased that for some chro...score of eight or greater, and those with an Ishak fibrosis score of three or higher. Based on logistic regression models, inflammation was predicted using the...