Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...study, reported today in the journal Nature,is the first to demonstrate how leptin initiates the burning of... In fact, their study shows that leptinis only the first step in a series of events that ultimately boosts fatmetabolism, according to study authors Sheila C...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...(SPIRAT), and involves two protocols. The first protocol will enroll 24 patients who are HIV-posit...zkrieg concoctionof medications as patients in the first protocol, followed by high-dosechemotherapy and radiation. These two steps should reduce the HIV "vi...Shark-Liver Substance May Slow Growth Of Brain Tumors
...nst human diseases, but this is believed to be the first evidence that squalamine may work against brain cancer. Squalus sharks' livers produce an oil used in manufacturing drugs, and small amounts of squalamine are found in shark cartilage. Squalamine dramatically slowed blood vessel cell growth without d...New Colorectal Cancer Treatment Available
New York, NY, June 17, 1996 -- For the first time in nearly 40 years there is a promising new d...dy that will evaluate the use of the new drug as a first line therapy for colorectal cancer patients with metastatic disease. The study will be supported by...Emory Doctors Discuss "Killing Heat" In This Week's NEJM
...orted to an air-conditioned shelter." "At the first sign of an increase in heat-related emergency department visits, efforts to reach high-risk individuals are intensified. Candidates for the shelter are actively sought out by visiting nurses, 'Meals-on-Wheels' and other service providers. Letter...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...e Johns Hopkins Oncology Center have developed the first under-the-skin narcotic drug implant for the treatment of pain in cancer patients. The researchers believe that the polymer implant could offer an alternative to external drug delivery systems used to treat serious pain and may be a potential techni...Discovery Hints At Multitude Of New Targets For Drugs
...mpounds that behaveddifferently from either of the first two classes. The compounds functionedas agonists in some cellular contexts, but as antagonists in others. Discovery of this third class has broad clinical implications, said DonaldMcDonnell, an associate professor of pharmacology in the Duk...What Makes Tics Tick? Clues Found In Tourette Twins' Caudates
For the first time, scientists have a neurobiological explanation for the variation in severity of tics in Tourette Syndrome. Researchers at the National Institute of Mental Health have traced such symptom differences to "supersensitivity" of certain neurotransmi...Tacrolimus Stops Rejection Of Kidney Transplants
...pal problems of organ transplantation. This is the first multi-center trial to demonstrate such encouraging results for persistent kidney rejection. The study, which involved 73 patients who entered the trial between September, 1993, and May, 1994, is reported in the September 15, 1996, issue of Transplant...Study Shows Major Savings In Supervising TB Care
...." Researchers at Johns Hopkins have shown for the first time that spending more time and money up front to keep tuberculosis patients on strict drug regimens saves money in the long run. The cost-effective strategy, called directly observed therapy (DOT), cures more people sooner and decreases the risk o...Fertilization Protein Structure To AID in Leukemia Treatment
...e animal kingdom, including in humans. One of the first events is that a flood of calcium ions is released as a signal tothe egg to prepare to begin dividing. The flood of ions is controlled by a regulatory molecule, a sort of molecular switch, termed a secondary messenger. The secondary messeng......oms develop quickly and aggressively -- within the first one to two years of life -- and those in whom symp...hymic-defect group would develop AIDS before their first birthday and 38 percent would die; 96 percent would develop AIDS before their second birthday and tw...Rape Victims Find Relief From Posttraumatic Stress Using The Antidepressant Zoloft.
...aumatic stress disorder(PTSD) participating in the first medication study dedicated solely to thatpatient group, report Barbara O. Rothbaum, Ph.D., and her colleagues in theDepartment of Psychiatry and Behavioral Sciences, Emory University School ofMedicine, in the October issue of the Journal of Traumatic...KUMC Researchers Announce Breakthrough Method For Predicting Epileptic Seizures
...and associate professor of neurology. "This is the first time anyone has been able to predict when a seizur...ted all types of seizures tested. "This is a giant first step for improved treatment for epilepsy," said Susan Arthurs, a patient of Osorio's and founder and...UW, Siemens Unveil New Panoramic Ultrasound Imaging Application Using Programmable Technology
...t allowsultrasound medical imaging systems for the first time to be programmed formultiple diagnostic appli..., working with ultrasound technicians, created the first application,SieScape imaging, which was demonstrated today at a joint press conferenceon the UW camp...It Matters Where, In America, You Suffer A Heart Attack
...re given a diagnostic catheterization during their first (initial) hospitalization following a heart attack...number of days patients stayed in the hospital the first time they were admitted. Average costs of care (hospital and physician) during the initial hospi...Premature Birth Sometimes Can Adversely Affect Infant's Ties To Mother
... rates of secure parent-infantrelationships in the first two years. "At 19 months, 75 percent ofnormal full-term babies were rated as secure, but attachment security forvery low birth-weight babies was just under 50 percent. At 14 months, thedistributions of the two groups were about the same, but there wa...Johns Hopkins To Announce AIDS Capitated Care Program
Johns Hopkins has established the region's first AIDS care capitation programfor patients covered b...te-supported health insurance plan.Also one of the first in the nation, the program will use Hopkins specialistsand its network of sub-specialists to provide...Program Provides Treatment For Prison-Released HIV-Positive Women
...HIV-positive women released fromprison. During the first year of the program, 41 HIV-positive women were re...group home. Women in the prison release program's first year had recidivism rates of 12percent within six months and 17 percent within 12 months. For compar...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
...sedshort-term mortality. However, ACTG 315 is the first studyto probe the immunologic consequences of such...the ACTUs that comprise the ACTG. "ACTG 315is the first field-test of this new scientific capability withinthe ACTG," comments NIAID's Lawrence Fox, M.D., P...