Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...se animals and likely in obese humans, researchers found -- a theoryconfirmed by studies showing that obese humans have elevated leptin levels yet remain obese.Researchers around the country theorize that leptin remains elevated because the fat cells neverreceive its "slimming" signal. In studying the le...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...ecomes resistant to drug therapy." HIV is found in three "compartments" in the body, Bartlett said.The largest is the lymphoid tissue, such as nodes, liver and spleen. Theothers are plasma and peripheral blood cells. While clinical trials are underway at other centers to test the effects...Shark-Liver Substance May Slow Growth Of Brain Tumors
...cturing drugs, and small amounts of squalamine are found in shark cartilage. Squalamine dramatically slowed blood vessel cell growth without damaging healthy cells, according to Henry Brem, M.D., co-author of the studies and director of neurosurgical oncology at Hopkins and Allen K. Sills, M.D., lead autho...Digital Speech Analysis Tests Sobriety
...Now, if you ever got really, really lucky, and you found somethingthat you only ever saw in intoxicated speech ... then you would be ableto just do it on the fly," Cummings said. "But I haven't seen anythinglike that yet." More importantly, researchers have to compare their results againstother factors th...Use Of Surfectant Therapy Widens Gap In Death Rate Of Black And White Newborns
...introduction of surfactant therapy, theresearchers found that the overall mortality rate of premature infan... in the death rate of premature black infants. "We found that this therapy, which has been shown to be effective,did not have the anticipated effect on the d...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...is is an easy way to administer a drug, and it was found to be safe and effective," says Dobs, the lead author. Results of the study, funded by the National Institutes of Health and Watson Pharmaceuticals, will be presented June 12 at the International Congress of Endocrinology's annual meeting in San Fran...New Colorectal Cancer Treatment Available
...y the anti-tumor activity of CPT-11 which has been found in patients who have received prior therapy as well as those who did not," said Dr. Saltz. Colorectal cancer is the second leading cancer killer in the U.S. Each year 133,550 men and women in this country are diagnosed with the disease and in many ...Discovery Hints At Multitude Of New Targets For Drugs
...gy to explain how a single kind of steroidreceptor found throughout the body can produce such different effects indifferent tissues by assuming different conformations. "Let's say a receptor needs to be in a 'square' conformation to produceall the processes that it normally produces. If a ligand c...What Makes Tics Tick? Clues Found In Tourette Twins' Caudates
...eagues in the NIMH Clinical Brain Disorders Branch found that binding to D2 dopamine receptors in the caudate nucleus was higher in the sibling with the more severe symptoms. "Strikingly, the degree to which the twins differed in this caudate D-2 binding predicted almost absolutely their differences in t...Tacrolimus Stops Rejection Of Kidney Transplants
...idney study from the University of Pittsburgh that found nearly identical results. Previous studies in liver transplant recipients have also demonstrated a similar results. Transplant centers participating in the study include the University of Chicago, the University of Alabama at Birmingham, Johns Hopkin...Scientists Produce New Anti-Malarial Compound
...er, a structure called a peroxide. The researchers found that iron from blood inside the malariaparasite pr...cted blood to other people.Anopheles mosquitos are found in portions of the United States,where reports of malaria have historically been rare but wherepubli...Study Shows Major Savings In Supervising TB Care
..., associate professor of medicine. The researchers found that using DOT throughout the United States would save $25 million compared with conventional therapy, save 240 additional lives, and prevent 2,400 relaspes, including 100 with drug-resistant TB. "Many doctors and health departments have felt that DO......posed to, though not infected with, HIV. The team found a similar distribution of CD8+ T cells among the t...out 15 percent of all HIV-infected children. They found that 82 percent of infants in the thymic-defect group would develop AIDS before their first birthday...Stents Work Well, But Are Costly: Will Hospitals Continue To Use Them?
...nt. Analyzingthe results in about 400 patients, he found that stenting costs about $13,000-- roughly $2,000...scious." In looking at medical records, Peterson found out that the extra costof stenting is not due to medication or length of hospital stay. It is inthe ...It Matters Where, In America, You Suffer A Heart Attack
...at happened to them up to one year later. They found that the rates of death and second heart attacks w...ppens to a patient over the span of a year. "We found evidence of a patient management strategy on the West Coast that seems to strike the best balance be...Premature Birth Sometimes Can Adversely Affect Infant's Ties To Mother
...els and Margo Dicthellmiller. Previous studies had found little differencein the quality of parent-infant attachment between premature infants ofless risk and normal infants. The researchers observed infant-mother interaction in homes and in a laboratory.All of the infants had spent an average of three mo...Hospital Noise Disrupts Sleep For Patients, In The Critical Care Setting
...g an eight-hour period, from 10 p.m. to 6 a.m., we found that loudnoises markedly disrupted the sleep of pa...usals from deep sleep in six elderlypatients. They found a very strong correlation between the number of soundpeaks and sleep arousals. For example, not coun...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
... In the three-month analysis, Dr. Lederman's group found that the increase in CD4+ T cells couldbe attributed to both more memory cells (those that have encounteredHIV before) and more naïve cells (those not exposed to HIVor another antigen before), while naïve cells are primarilyresponsible for ...Childhood Sex Abuse Impacts Adult Relationships
...male acquaintances." Specifically, the researchers found that on measures of how safe and secure women feel...le. Through statistical analyses, the researchers found this difference to be largely explained by the quality of adult attachment relationships. And consis...NIAID Stops AIDS Study Prematurely Because Drug 'Cocktail' Boosts Survival
...drug clinical trial early because researchers have found a three-drug "cocktail" including the protease inh...h clinician Janet Groves. Nationwide, researchers found 63 "disease progression events" -- including AIDS-related illnesses and deaths among patients receiv...