Hormonal treatment improves survival in high-risk prostate cancer patients
April 1, 2005 Administering hormonal treatment in addition to radiation therapy in pati...radiation therapy and goserelin acetatc, a type of hormonal agent. The patients in the observation arm received radiation therapy only. Goserelin acetatc was ad...Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
... usually demarcates which patients will respond to hormonal therapy. And, to date, no cases of congestive heart failure or other such serious heart problems have yet been observed in the patients, Buzdar says. Within several months, the research team will launch additional studies, enrolling larger groups of ...Earlier use of prostate cancer vaccines urged by Hopkins scientists
... attack on cancer cells, and it occurs right after hormonal therapy begins to wipe out the tumor and immune cells outnumber cancerous ones," according to Charles Drake, M.D., Ph.D., assistant professor of oncology and director of the research which is published in the March issue of Cancer Cell . In the Hopk...Postmenopausal breast cancer survivors at increased risk for bone fractures
...e history lifestyle, medication use and the use of hormonal replacement therapy, the researchers found. Other factors, including age, ethnicity and depression, were associated with increased risk of fractures among breast cancer survivors. "An increased risk for total fractures was observed in all ages of bre...Other highlights in the March 2 JNCI
...er even after taking into account reproductive and hormonal risk factors. The authors conclude that a component of breast density that is independent of estrogen-mediated effects may contribute to breast cancer risk. Contact: Eve Harris, Public Affairs, University of California, San Francisco, 415-885-7277, ...Female sex hormones play a vital role in defense against sexually transmitted diseases
... than men. "The results directly indicate that the hormonal conditions that provide protection against primary exposure to sexually transmitted viral infections may be very different than those that may be useful in vaccination strategies," said Kaushic. "There is of course the flip side to this as well. Our ...Hypothyroidism associated with reduced breast cancer risk
...g research that brought therapeutic and preventive hormonal approaches to the patient - many more studies need to be done to explore the role of other hormones. The influence of thyroid gland disease on breast cancer has been debated for some time. Other smaller studies have focused on a population of women w...Bone density returns when teens stop using Depo Provera, Group Health study finds
... It's not clear from studies to date whether other hormonal methods of birth control might affect bone density, Scholes said. She and her colleagues are currently conducting a study of the effect of oral contraceptive use and discontinuation on women's bone density. Scholes noted that a recent U.S. Surgeon G...Over-the-counter supplement appears effective in treatment of midlife-onset depression
CHICAGO The over-the-counter hormonal therapy known as DHEA may be an effective treatment of midlife-onset minor and major depression, according to a study in the February issue of The Archives of General Psychiatry, one of the JAMA/Archives journals. DHEA (dehydroepiandrosterone), an ad...Making emergency contraception readily available does not increase unprotected intercourse
..., who were not desiring pregnancy, using long-term hormonal contraception, or requesting EC. The participants were assigned to one of the following groups: (1) pharmacy access to EC; (2) advance provision of 3 packs of levonorgestrel EC; or (3) clinic access (control). The researchers found that women in ...Poor response to chemotherapy does not mean poor outcome for patients with rare breast cancer
...change in the clinical approach may involve use of hormonal therapies, Cristofanilli says, because the team pr...itive (typically a better prognosis group). Use of hormonal therapies such as aromatase inhibitors "may represent an interesting approach to treating invasive l...Decreased sensitivity in the brain to estrogen may help explain menopausal changes
...ugh menopause. The study provides new clues about hormonal influences on hot flashes and night sweats experie...r most of the cycle than in the other groups. The hormonal patterns in groups 2 and 3 suggest different kinds of reduced sensitivity to estrogen (or abnormal e...Women seeking treatment for even minimal 'male-type' hair growth need endocrine evaluation
...esence of other subtle changes may be a sign of a hormonal imbalance linked to a variety of serious side effe...complain of unwanted hair growth, receive in-depth hormonal evaluation. The single best predictor of an androgen excess disorder among patients with minimal exc...Re-analysis of large trials shows greatest benefit of chemotherapy in ER-negative tumors
...e study proves that breast cancer patients of both hormonal types are being aided by clinical advances. "The prevailing wisdom has been that science has focused on ER-positive tumors, with development of SERMs and now aromatase inhibitors, but ER-negative patients have been left in the lurch," Berry says. "No...Molecular test predicts risk of breast cancer recurrence and who will benefit from chemotherapy
...ited States do receive chemotherapy in addition to hormonal therapy. Using samples from 447 patients and a collection of 250 genes in three independent preliminary studies, 16 cancer-related genes were found that worked best. The scientists created a formula that generates a "recurrence score" based on the e...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
... unknown early-stage breast cancer. AROMASIN is a hormonal therapy that belongs to a class of drugs called ar...rs, treatment with tamoxifen has been the standard hormonal therapy for postmenopausal women with breast cancer that is dependent upon estrogen for growth. Resu...Sleep duration affects appetite-regulating hormones
...a hormone thought to stimulate food intake). These hormonal differences are likely to increase appetite, which could be responsible for the increased BMI in short sleepers. These findings could explain, at least in part, why societies in which excess calories are much easier to come by than a good night's s...Sleep loss boosts appetite, may encourage weight gain
...se two hormones and to correlate the extent of the hormonal changes with the magnitude of the hunger change," ...d a series of studies describing the metabolic and hormonal consequences of chronic partial sleep loss which is now common. Such studies include: A 1999 stu...Does the lack of sleep make you fat?
...ey were also found to have 15% less leptin. These hormonal changes may cause increased feelings of hunger, leading to a foraging in the fridge for food. Dr Taheri, lead author of the study, said: "We found that people who slept for shorter durations have reduced leptin and elevated ghrelin. These differenc...Endocrine Society calls for clinical guidelines on androgens for women
...and conduct basic and clinical research on complex hormonal disorders, today called for new clinical guideline...terone deficiency and would therefore benefit from hormonal therapy. In addition, the therapeutic window for testosterone in women is small and it is easy to c...