Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
... in the journal Nature,is the first to demonstrate how leptin initiates the burning of stored fat, a proc.... Currently, Collins and Surwit are investigating how defects in the feedbackloop may be involved in diet-induced obesity. The Nature study reported today...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...archers hope to increase science's understandingof how the virus reacts to both drug treatments and novel forms of reconstitutingprotective immunity. "We are pushing the envelope of what is known and what can be imaginedin effective therapy," said Dani Bolognesi, director of the Duke Centerf...DNA Imaging to Design Better Drugs
Designing drugs and knowing exactly how they work may have justgotten easier, thanks to re...have developed a new way to examine andquickly map how nucleic acid ligands, in some cases anti-cancer drugs,bind to and alter DNA at the molecular level. ...Digital Speech Analysis Tests Sobriety
...ppens duringspeech production at your vocal cords, how steadily you can produce theexcitation (air from y..., as part oftheir ongoing study of ways to measure how alcohol consumption affectsspeech. The current project is sponsored by the Alcoholic BeverageMedical...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...organ of the animal, and make ameasurement. That's how we do it." Doctoral candidate Maria Theresa Lee has the difficult jobof producing the probes which are so fragile they have to beencased in a tiny capillary of glass. "You can hardly see thefibers," remarked Lee. "It's very difficult when you're maki...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...l not need to store medicines or remember when and how to take them. The new drug delivery system is also appealing to Indian physicians because it reduces concerns about illegal sales of these drugs. Following the successful completion of U.S. trials, the researchers hope to make the polymer available ...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...hat twitch, cry or act fussy can further influence how parents treat thebaby. "A baby that isn't cuddly sweet can turn off a parent," Lester said. "For adrug-using mom, this is a real setup for failure, as problems with thebaby and mother can trigger negative parenting. The trick is to get the mothersbac...Discovery Hints At Multitude Of New Targets For Drugs
DURHAM, N.C. -- A new study of how drugs plug into the human progesteronereceptor in the cell supports a new and different view of how drugs andhormones act on steroid hormone receptors that trigger cellular responses. The new...Raising The Retirement Age In The United States Could Save Billions In Social Security Payments
... to 72. He acknowledged that it's hard to predict how such changes would be receivedby the American public. "The trend actually has been in recent years that the proportion ofpeople retiring not just at age 65, but at 62 and 59, has increased. Butpart of the reason why this has occurred is because some......s. Until now, doctors have not known conclusively how to predict which HIV+ infants will fall into which category. Thymus dysfunction was common to the majority of HIV+ infants whose AIDS symptoms progressed rapidly, reports Athena P. Kourtis, M.D., Ph.D., fellow; Andre J. Nahmias, M.D., M.P.H., direct...Stents Work Well, But Are Costly: Will Hospitals Continue To Use Them?
...son warned. "Sadly, hospitals now need to look at how everydollar is spent, and 'stenting' may become a ...decisions on whether to use a stentor not based on how much money their hospitals make or lose, Peterson said.In part, that's because the costs of stenting...UW, Siemens Unveil New Panoramic Ultrasound Imaging Application Using Programmable Technology
...he UW core technology. "This is asuperb example of how industrial and university partners can work togetherto develop technologies for the needs of tomorrow," said Yongmin Kim. "Itwas truly a joint effort that maximized the special expertise of eachorganization." Koob agreed, saying, "The collaboration w...It Matters Where, In America, You Suffer A Heart Attack
...LEANS -- Where you live in America helps determine how a doctor treats your heart attack, how long you stay in the hospital, and whether you are likely to need further hospitalization in the nex...Postmature Infants Not As Easily Calmed As Other Newborns
...alming effect in postmature infants while studying how babiesdevelop early attachments to their mothers. ...ifficulties of the postmaturebabies while studying how infants develop early attachments totheir mothers. The mother's milk actually tastes sweeter than th...Premature Birth Sometimes Can Adversely Affect Infant's Ties To Mother
...chers report. The findings provide new insight on how medical technology's ability tokeep increasingly younger babies alive may impact early cognitive development.Researchers gathered information about 37 babies, who weighed an averageof 2 pounds at birth and were born 13 weeks early in the normal 40-we...Benefits Of New Diet Drug Don't Outweigh Risks
...ically, perhaps for a lifetime. To determine just how much weight people could expect to lose if they took Redux or a similar drug for a long time, Levitsky analyzed the studies from all the articles published in scientific, peer-reviewed journals in which patients remained on fenfluramine for more than...Hospital Noise Disrupts Sleep For Patients, In The Critical Care Setting
...usals in one hour. Medical personnel aren't sure how disrupted sleep affects elderly patients.Some studies show that at least one-third of sleep-deprived hospital patientshave what is called "ICU psychosis," marked by symptoms of nighttimedisorientation and delusion. Sleep deprivation may also adversel...Childhood Sex Abuse Impacts Adult Relationships
...ldhood. "In other words, our findings suggest that how sexual abuse affects overall mental health in late...fically, the researchers found that on measures of how safe and secure women feel in an intimate relationship, sexually abused women scored about half the ...Laser Shown Effective In Patients Who Are Not Candidates For Bypass Surgery Or Angioplasty
...eation of the channels. Once we figureout exactly how and why it works, we can then make it work better." Since it takes time for the new capillaries to grow, patients usuallydo not begin to see major improvements until three months after the procedure,and the improvement typically continues for n...Study Shows Gum Disease Increases Risk Of Future Heart Disease
...ese findings together as a possible explanation of how bacteria that cause periodontal disease can also increase the risk for heart disease." Genco has been following this population of American Indians since 1982, first as a consultant to the National Institutes of Health when severe periodontal di...