Shark-Liver Substance May Slow Growth Of Brain Tumors
...exploring natural shark substances for use against human diseases, but this is believed to be the first evidence that squalamine may work against brain cancer. Squalus sharks' livers produce an oil used in manufacturing drugs, and small amounts of squalamine are found in shark cartilage. Squalamine dramati...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
... are reported in the July 1996, issue of Pain, and human trials should begin within a year, he said. Grossman and his team began developing the pain polymer five years ago as an inexpensive, abuse-resistant way of offering pain management to people in developing nations, where cancer rates are high, but li...Discovery Hints At Multitude Of New Targets For Drugs
...AM, N.C. -- A new study of how drugs plug into the human progesteronereceptor in the cell supports a new and different view of how drugs andhormones act on steroid hormone receptors that trigger cellular responses. The new view holds that steroid receptors are not merely on-off switches,but are fa...Fertilization Protein Structure To AID in Leukemia Treatment
...f a marine mollusk and a protein on the outside of human white blood cells. The work is published in the November issue of Nature Structural Biology. The egg protein is from the California sea snail, Aplysia californica , an animal used by biologists to study the process of fertilization. T...Premature Birth Sometimes Can Adversely Affect Infant's Ties To Mother
...but I amstruck by the remarkable resilience of the human organism," she said."Some of these babies were the size of your hand when they were born,and they had been hooked up to machinery to keep them alive. Yet we latersaw them running around in the lab at 3 years of age. When my student codingthe videotap...Childhood Sex Abuse Impacts Adult Relationships
...t Feerick, a doctoral student in the department of human development and family studies, and her adviser, Jeffrey Haugaard, associate professor. Although other researchers have looked at the impact of sexual abuse on behavior problems and adjustment difficulties, the Cornell researchers believe their study...NIAID Stops AIDS Study Prematurely Because Drug 'Cocktail' Boosts Survival
...es the virus' genetic material, or RNA, to convert human genetic material known as DNA into more virus. The Food and Drug Administration approved use of the combined ZDV and 3TC in November 1995, in part because of a national study Eron led and published in the New England Journal of Medicine. Indinavir h...Common Carbohydrates May Prove To Be Substitute For Dietary Fiber
...searchers are finding a growinglist of benefits to human and animal digestive systems from certain formsof indigestible oligosaccharides -- naturally occurring groups of carbohydratescontaining simple sugar molecules -- found in many fruits and vegetables. For years, oligosaccharides were thought to give ...Kids Near Airports Don't Read As Well
...Tolle and Pegauy Santil, 1996 Cornell graduates in human ecology, who were both seniors at the time. When the data were analyzed, the researchers controlled for mother's education. "Interestingly, the findings were only significant for speech perception amidst noise, not sound perception" says Maxwell. "......oach does nottotally rely on the intervention of a human to extract and define a setof features for it. Thi... voluminous to bedisplayed in a zoom-in format for human review. GTRI's system would provide a high confidence pre-screen capabilityfor this high resolution...Study Injects New Interest In How Vaccines Work
...ved by the Food and Drug Administration for use in human vaccines. The FDA limits the dosage to 0.85 millig...curring form of aluminum found in small amounts in human and animal tissue -- Hem was able to extrapolate how much of the aluminum in the vaccine the rabbit ...Milk Extract May Heal Wounds And Smooth Wrinkles
...ir way down the track, and depend on the successof human trials. Dr Belford says the main ingredients which make the extract work as ahealing agent are a cocktail of different "growth factors", purifiedfrom the whey. Growth factors are naturally occurring chemicals which promote cell growthand skin repai...New Approach To Multidrug Resistance
... brain tumors. Preliminary results fromanimal and human studies, using paclitaxel (Taxol), doxorubicin and...ermine the most effectivecombination of drugs, and human clinical trials to determine the effectivenessof this approach in various natural cancers. The Dart...Psychiatric Symptoms May Signal Brain Damage From Diet Pills
... studies show that they do in rodents. And since human brains are more like those of monkeys, any such damage in humans would also likely be permanent, according to McCann. "However, the neurotoxic potential of fenfluramines in humans has not been systematically evaluated," write the researchers. More...Antioxidant-Enhancing Drug Partly Rescues Noise-Induced Hearing Loss
...the action of R-PIA likely would be similar in the human ear. "In the future, we may be able to rescue the hearing loss of personsinadvertently exposed to large amounts of noise, such as those near anexplosion, for example, through the use of this drug." Noise-induced hearing loss, a majo...NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...e somatic ACE gene-a findinglater confirmed in the human gene. To determine whether testis ACE has any real importance in malereproduction, Bernstein created recombinant knockout mice containing no somaticor testis ACE gene. He found that the male knockout mice fathered litters withmuch smaller numb...Intralase Will Develop Laser Systems For Eye Surgery
...ent also approved by the Board of Regents. Future human clinical trials also are planned pending review and approvals by the Food and Drug Administration and the U-M's institutional review board. CUOS was established in 1991 with funding from the National Science Foundation (NSF) and the State of M......fects of these factors will lead to an increase in human lifespan," the draft report said. Section III asked respondents to estimate mortality improvement ratesfor the three countries by age group, gender, and the population as a whole. Alower level of response combined with a wide range of estima...Rats Receiving Ginkgo Biloba Learn Quicker, Live 20 Percent Longer Than Controls, UB Study Finds
...-related deterioration in brain function. Several human trials there have shown positive results, but little research has been done to replicate these findings in animals, Winter said. Winter's earlier research with rats showed that a set of tasks performed in an apparatus called the radial maze cou...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...indings; an IND designation permitscommencement of human clinical trials. As part of the agreement, Targon will be granted an option to license products and technology from directly funded programs. Additionally, Targon will receive a right of first review of certaininventions in the field of can...