New study in 'Nature' demonstrates protection against cell death during heart attack
...lso blocks calcineurin, an agent that protects the immune system. Fortunately, there are so-called analogs ...rin that block cyclophilin D but do not affect the immune system. While these drugs have not yet been tested in humans, there have been numerous studies indic...Suppressing the cells that trigger cat allergy
... early exposure may somehow modify an individual's immune system to tolerate specific antigens. Various attempts to modify abnormal immune responses to specific allergens, such as those to cat dander, have been made. Investigators have pre...Novel therapy tested in mice could chase away cat allergies
...va or dander (small scales from skin or hair), key immune system cells respond by spewing out histamine. All...ults suggested that GFD successfully prevented the immune cells from reacting to cat allergen. The next step was to test GFD in mice that we had made allergic...Optical technique identifies vulnerable plaques in cardiac patients
...l covering the lipid pool, and infiltration of the immune cells called macrophages. The OCT images showed that the heart attack and ACS patients had more lipid in their plaques and significantly thinner fibrous caps than did the stable angina patients. Overall, vulnerable plaques were identified in 72 perc...Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
...ems with immunosuppression, in which every human's immune system might attack stem cells from sources other ...elopment, mesenchymal stem cells do not trigger an immune response, unlike what would happen if more developed stem cells were used. "While the bone marrow ...Research offers hope of new treatments for liver damage
...first time, identified two separate populations of immune cells --macrophages--in the liver. One group of ma...causes scarring to the liver, but the next wave of immune cells, produced only a few days later, change function to break down and reabsorb the scarring. The...Risky surgery not always necessary to treat cervical disease
...de the prophylactic vaccine which focuses on human immune responses that may help prevent HPV infections. T...ther is a therapeutic vaccine which stimulates the immune responses to eliminate already infected cells. Researchers comment that while surgery has been the s...NIAID initiates trial of experimental avian flu vaccine
...st the vaccine's safety and ability to generate an immune response in 450 healthy adults aged 18 to 64. If the vaccine is shown to be safe in adults, there are plans to test it in other populations, such as the elderly and children. H5N1 avian influenza leads to severe disease in both birds and humans. Betw...WISE study starts in Toulouse: 60 days of bed-rest for terrestrial female astronauts
...r condition, coordination of movements, changes in immune system, bone formation and psychological wellbeing. External experts reviewed all scientific protocols of the study prior to selection, and the responsible French ethical committee in Toulouse has approved the integrated study design of WISE. With t...Scientist works on innovative treatments for brain tumors
..., a naturally occurring protein that regulates the immune system in the body. Normal cells do not have these same receptors. Debinski developed a drug that combines a form of Il 13 with a toxin that kills cancer cells. By targeting the therapy to these receptors, the drug finds and kills the cancer cells. W...Alcohol relapse adversely affects 10-year liver transplant survival
...bitory effect of alcohol on various aspects of the immune system, as suggested by previous studies. "In conclusion, we have observed a significant decline in 10-year survival rates in patients transplanted for ALD who relapse into alcohol use, as compared with those who remain abstinent," the authors state....Donor age has no affect on long-term liver transplant survival
...s, may have allowed an early reconstitution of the immune system and its exposure to a large number of HCV [hepatitis C] infected liver cells, leading to immune mediated severe liver damage and thus to more frequent and severe forms of HCV recurrence." The aut...Chemical decoy shows promise for slowing Alzheimer's by acting as decoy
... tried in animals, but these have triggered severe immune responses that have prevented their use. "We are currently trying to make decoys with higher affinity and specificity for beta amyloid by modifying the chemistry. Eventually we think we'll be able to make better decoys using molecular design," Good s...Protein that helps skin cancer spread identified by Stanford researchers
...s children with RDEB or people who are chronically immune suppressed due to organ transplantation. Despite this optimism, Khavari cautions that many further experiments are needed before this work could lead to any cancer treatment....Patient with drug-resistant form of HIV identified
...ingly versatile foe, one that can mutate to escape immune attack or to acquire drug resistance with surprising speed. One lesson to be drawn from this case, therefore, is that despite all the advances that have been made in understanding this virus and all the progress that has been made in developing new d...Chemists identify immune system mechanism for methamphetamine binges
...have found evidence in laboratory studies that the immune system may be able to recognize methamphetamine an...mented the drug's apparent ability to suppress the immune system, making abusers more vulnerable to diseases such as HIV. The new study is the first to sugges...Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
... of these cancer risks with the use of HAART, with immune status, and with behavioral risk factors such as s... AIDS epidemic and how the knowledge of cancer and immune diseases has grown since it began. They note that questions remain about the types and severity of ...Epstein-Barr virus protein crucial to its role in blood cancers
...ism by which EBV transforms human B cells from the immune system into cancerous cells, which can lead to development of B-cell lymphomas. Erle S. Robertson, PhD, Associate Professor of Microbiology and Director of Tumor Virology, with Penn's Abramson Cancer Center and MD/PhD student Jason Knight, published ...Earlier use of prostate cancer vaccines urged by Hopkins scientists
...rrow for vaccination, designed to reinvigorate the immune system's attack on cancer cells, and it occurs rig... hormonal therapy begins to wipe out the tumor and immune cells outnumber cancerous ones," according to Charles Drake, M.D., Ph.D., assistant professor of onc...Tumor-targeted immune cells cure prostate cancer in mice without causing systemic immune suppression
..., a Northwestern University researcher has endowed immune cells with the ability to specifically target meta... prostate cancer in mice without causing the toxic immune suppression that has been associated with earlier forms of cancer gene therapy. Chung Lee, John T. ...