Tag: "immunoglobulin" at medical news
JCI table of contents, January 20 2005
... of DNA as well as what is known as the Fc part of immunoglobulin
G, and that stimulation of dendritic cells in this manner caused the production of many proinflammatory factors that likely contribute to the development of SLE. The study will appear online on January 20 in advance of print ...
Multi-center study finds therapy boosts kidney transplants in 'highly sensitized' patients
...nistered either the medication, called intravenous immunoglobulin
(IVIG), or a placebo while awaiting transplantatio...ing organisms called antigens. A processed form of immunoglobulin
made from blood plasma can be administered to boost the body's natural levels. Researchers led by Dr...
IgG treatment during pregnancy reduces severity of rare, recurring liver condition in newborns
CHICAGO --- Treatment with high-dose immunoglobulin
G (IgG) during pregnancy lessens the severity of hemochromatosis (NH), a rare, devastating gestational disease with abnormal iron accumulation in the liver and severe liver injury that almost always results in fetal death or acute liver failure in ne...
Immune therapy appears to reduce risk of second attack of multiple sclerosis symptoms
CHICAGO Intravenous immunoglobulin
therapy may reduce the risk of a second attack of ...ract dysfunction, the article states. Intravenous immunoglobulin
(IVIg) has been reported to diminish the symptoms of MS in patients with relapsing-remitting MS (whe...
Mayo Clinic researchers restore lost immunity -- Possible breakthrough for AIDS
...r. Cascalho. "Now we know that the B cells and the immunoglobulin
that they produce can help reconstitute immunity b...to a diversity of T cells through means other than immunoglobulin
isn't known. A Second Possible Approach Dr. Cascalho theorizes that the gamma globulin might also...
Poor prognosis for depression linked to an autoimmune thyroid condition?
... of thyroid hormone and thyroid binding inhibitory immunoglobulin
in their blood. By creating an algorithm based on...epressants with an almost 90% success rate. Higher immunoglobulin
levels were associated with a reduced responsiveness to treatment, indicating that specific therapeu...
Studies show Tim-3 proteins key to immune responses
...issue of Nature Immunology. Known as Tim-3 (T cell immunoglobulin
domain, mucin domain), the proteins in question are found on the surface of TH1-helper type T cells, which when activated become the body's first line of defense against foreign microbes. "Activated TH1-type helper T cells both participate in and he...
Guideline: Early treatment for Guillain-Barr syndrome may speed recovery
...at two treatments plasma exchange and intravenous immunoglobulin
(IVIg) are equally beneficial for adults with severe, early GBS. These treatments could also be considered for treating children with severe GBS. "This means that people who are severely affected should be treated early with either IVIg or plasma ex...
Panel of leading neurologists pronounce best treatment for Guillain-Barr Syndrome
...ogy.org . "The bottom line here is that IVIg, or immunoglobulin
infusion, is the preferred treatment for Guillain-Barr, depending on availability," says Eelco Wijdicks, M.D., a Mayo Clinic neurologist and second author of the paper. Availability of IVIg treatment is compromised at times by shortages of gamma glob...
NIAID opens innovative treatment study for West Nile virus
...ompany partnering with NIAID on this study, has an immunoglobulin
product that contains antibodies to WNV. Omrix developed this immunoglobulin
treatment from the plasma of Israeli donors who have high levels of antibodies to WNV. WNV has been ...
Moores UCSD Cancer Center launches human trial for prostate cancer vaccine
...n this case, the B cells are expected to churn out immunoglobulin
studded with a piece of telomerase, which will trigger an immune response against the cancer cells. While it is early in the clinical testing of this approach and researchers aren't making any promises, they are optimistic about its potential, and s...
Newly approved psoriasis drug invented and tested at Univ. of Michigan
...e heads of two LFA-3 molecules with the tail of an immunoglobulin
molecule that usually signals the immune system's ...of a circus clown's routine. In the meantime, the immunoglobulin
tail of the alefacept molecule sticks out, and signals natural killer cells and macrophages to come ...
Children with dogs, cats have reduced risk of allergies
...said. Immediate allergic reactions are caused when immunoglobulin
E, a class of antibodies that causes allergic responses, become bound to mast cells, a type of white blood cell. This coupling is needed because antibodies recognize allergens but it's the mast cells that release histamines and other chemicals that c...
American Thoracic Society Journal news tips for April (first issue)
...lergens. The women were also measured for specific immunoglobulin
E (IgE) antibodies to specific antigens under study. The research appears in the first issue for April of the American ThoracicSocietys peer-reviewed American Journal of Respiratory and Critical Care Medicine. DELAY IN DIAGNOSIS AND TREATMENT FOR TU...
American Thoracic Society Journal news tips for February (first issue)
...ave shown. This potent cockroach allergen elicits immunoglobulin
E (IgE) responses in 60 to80 percent of allergic patients even at very low levels in the environment. In asthma, many allergic reactions involve antibodies of the IgE class. (Cockroach allergen exposure is strongly linked to asthma attacks among sus...
Not all allergy tests are created equal, study suggests
... Each testing method detected the presence of immunoglobulin
E (IgE) for different allergens. IgE is an antibody that causes allergic symptoms. Each lab used their usual procedures to test the serum samples for IgE antibodies to 1...
Mayo Clinic scientists discover way to enhance immune system that repairs nervous system in mouse model
...quivalent or greater extent than human intravenous immunoglobulin
(IVIg), an established treatment for immune-mediated diseases. The antibodies bound to the surface of the cells that make myelin. The research also yielded the molecular sequence of the antibody which will facilitate production of the antibody in l...
Duke team seeks novel vaccine strategy for HIV
...ining their vaginas containsHIV-specific secretory immunoglobulin
A (IgA) antibodies that may be able tostop the virus and keep it from entering the bloodstream. It is possible thesewomen have become "naturally" immunized against future HIV infections.A research team led by Duke University Medical Center is hoping...
Scientists find protein in Epstein-Barr virus causes B cell lymphoma in laboratory mice
...n of B cells, which arewhite blood cells that make immunoglobulin
antibodies. Humans bearing a mutationpreventing CD40 function cannot produce effective antibodies. Because CD40 and LMP1 have been shown to interact with the same cellularproteins, the researchers crossed the mice to learn whether LMP1 could ...
Treatments reduce strep-triggered symptoms of OCD and tics in some children
... treated with plasmaexchange (PEX) and intravenous immunoglobulin
(IVIG). Dr. Susan Swedo andcolleagues at the National Institutes of Health reported their findings in theOctober 2 issue of Lancet. In previous studies, Dr. Swedo and others observed that in a small number ofchildren suffering from the obsessional t...