AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...at the same time destroying the cancer. "Wewant to kill the cells that house the virus as well as the cancer,"said Smith. Then, to restore a healthy immune system, Smith will give the patientsa transplantation of blood stem cells. Another alternative researchers areinvestigating is to use banked...Scientists Produce New Anti-Malarial Compound
... level. The new compounds use the samemechanism to kill the parasite that causes malaria, but they aremuch less expensive and easier to produce than drugs presentlyavailable. When tested in laboratory cultures of infected blood, theexperimental drugs killed Plasmodium falciparum, the species ofmosquito-bo...... The probe emits radio waves that heat and kill tumor cells. Watching the MRI video monitor, doctors can adjust the instrument to reach all parts of the malignancy while avoiding healthy tissue. As the physicians work, they can actually see the tumor die. Hines' previous surgeries had sid...Antimicrobial "Bug Spray" Found In Human Lung Cells
..., where infectious lung diseases like tuberculosis kill more than 7 million people every year. "People hav...echanism--they shoot out one or more peptides that kill bacteria." After the first such compounds were identified in cells from frog skin and cow throa...Targeted Protein Toxin Effective Against Persistent Brain Tumors
...he patients were later treated with ganciclovir to kill the tumor cells. However, this therapy worked only against very small tumors in four of the 15patients who were evaluated. The NINDS, one of the National Institutes of Health located in Bethesda,Maryland, supports a variety of research focused on imp...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
...ith the ideathat if the blood level is adequate to kill the virus, we've given enough of thedrug," he said. "Now the concern is that the brain level may be much lower andthat the virus could escape to the brain, continue to divide there and live on." Kim said he would next like to measure the leve...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...g of new drugs. Since traditional anti-tumor drugs kill tumor cells, we expect to see them killing cancer ...ut compounds that interrupt other pathways may not kill a tumor immediately, but rather cause it to shrink over time. Theendpoint of such treatment is harde...Researchers Study 'Natural' Screen For Cancer
...ain,using light rays to target the cells can help kill the disease. An orangelight forces hypericin to release oxygen "singlets" and decompose cancerouscells. A second study involves the use of a "diffused spectroscope" to studymelanoma, or skin cancer. Researchers developed the device, which is......her the dose of chemotherapy, the betterthe cancer kill rate is," Folz said. "In patients receiving this treatment forbreast cancer, what limits our ability to increase the doses of chemotherapy arethe negative side effects to the lungs and other tissues." The researchers believe that the c...Successful Cancer Therapy May Doom Later Treatments To Failure
...er agents that work well in the petri dish fail to kill cancer cells inthe body. The new findings suggest that such candidate drugsmay never get a chance to prove their cancer-killing powers because they havebeen engineered too large for the microscopic doors they have to pass through. Equally pe...Chemical Society's Highest Award Goes To Ronald Breslow
...novel approach to riddingthe body of cancer: don't kill the cancer cells, but make them normal. "It's very difficult to make a selective toxic compound -- that is, achemotherapy drug that kills cancer cells without killing normal cells," hesaid. This is true largely because cancer comes not from...New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
... will strike 178,000 women in theUS this year, and kill 43,500. Because breast cancer can take five or more years to become detectable, Cummingssaid that the study will continue for at least another four years to determinethe long-term benefits of raloxifene in women. He added that the women who arepar...ONYX Pharmaceuticals Reports Phase II Clinical Trial Results At ASCO Meeting
...inical studies, has been shown to replicate in and kill tumor cells deficientin p53 tumor suppressor gene ...apies to reverse the effects of the mutation or to kill thecancer cell. Onyx pursues a strategy of establishing corporate partnershipsthat provide compleme...New Treatment Targets Most Malignant Brain Tumors
...s, with only one or tworadioactive atoms needed to kill a cell. Preliminary results from clinicaltrials show that only a few millicuries of Astatine-211 on the antibody candeliver a radiation dose to tumors the equivalent of that delivered by 100millicuries of Iodine-131, said the researchers. Acc...New Study Designed To Improve Outcomes In Women With Metastatic Breast Cancer
...in the United States,breast cancer was expected to kill more than 40,000 women in 1997. Decades of researc...ates. The first requires high-dose chemotherapy to kill the cancer cells. The secondinvolves the administration of a vaccine to enhance the body's immunity...International Panel Evaluates Testing For Drug Resistance In HIV
...at directly measure whether a particular drug will kill a sample of the virusinfecting an individual patient. Each type has certain advantages anddisadvantages, but there are insufficient data to recommend one over the other. Resistance assays may identify the predominant resistant strains in a patientb...... studies and animal trials in mice, butit does not kill normal cells. "We will treat CML patients with this compound inthe form of a pill," said Druker. "We hope the compound will seek out the faultycells with the BCR-ABL protein and destroy them." "The highly specific drug therapy is a direct ext...New Study Indicates Lightning Can Kill Without Leaving a Mark
...ndon, the Colorado team proposedthat lightning can kill without a visible sign of electrical current enter... some of these occurrences." Lightning can kill at any altitude, the researchers stressed. In onecase cited by the authors in Lancet, a foursome of...Cereal Lessens Colon Cancer Risk
...uction"significant." Colon cancer is expected to kill more than 47,000 people in the U.S. this yearand is the third leading cause of cancer death for men and women, according tothe American Institute for Cancer Research and the American Cancer Society. Previous research has demonstrated that people with...Better Survival For Women With Breast Cancer -New Evidence On Chemotherapy
...th. The other way is to use a cocktail of drugsto kill the cancer cells ("chemotherapy"). In the largest ever randomised study of chemotherapy for cancer, an international collaboration organised by the Imperial Cancer Research Fund'sClinical Trial Service Unit at Oxford University, followed 18,000 women...