Shark-Liver Substance May Slow Growth Of Brain Tumors
...ical oncology at Hopkins and Allen K. Sills, M.D., lead author and a Hopkins neurosurgery resident. "We're encouraged by these initial findings," says Brem, who successfully uses time-release polymer discs to deliver a different anti-cancer drug directly to the brain to fight malignant tumors in people. P...Study Says Machine Sensors Applicable To Human Ills
...ate's ARL, a Navy-oriented facility, was chosen to lead the PredictiveDiagnostics Team because of its success in transferring military technologyto civilian applications. ARL, which was 50 years old last year, has madesignificant contributions to fluid mechanics and acoustics that have beenapplied to nava...Digital Speech Analysis Tests Sobriety
... digitally quantify this telltalesign, which could lead to a simple, non-invasive way to test a person'ssobriety. "This is basically an effect of fine motor control," said KathleenE. Cummings, a lecturer in Georgia Tech's School of <AHREF="http://www.ee.gatech.edu/"> Electrical and ComputerEngine...Use Of Surfectant Therapy Widens Gap In Death Rate Of Black And White Newborns
...sed in clinical practice," saidAaron Hamvas, M.D., lead author of the study and assistant professor ofpediatrics. Surfactant therapy is given to premature infants with respiratorydistress syndrome (RDS). The breathing disorder strikes up to 50,000 of the250,000 premature infants born annually in the Unite...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...lse it just flies away." Lee hopes her probes will lead to the development of evenbetter imaging agents, because the probes will show radiologistswhat happens chemically to the imaging agent as it travelsthrough the bloodstream. Scientists in the department ofradiology in UC's College of Medicine are rese...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...as found to be safe and effective," says Dobs, the lead author. Results of the study, funded by the National Institutes of Health and Watson Pharmaceuticals, will be presented June 12 at the International Congress of Endocrinology's annual meeting in San Francisco. Thirteen men with low testosterone recei...New Colorectal Cancer Treatment Available
...e at Memorial Sloan-Kettering Cancer Center is the lead investigator of a large-scale, international, mult...y treatment has failed," said Dr. Saltz who is the lead investigator of the study. "But we also need to know more about the usefulness of CPT-11 when used ...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...didn't actlike them," said Beata Napiorkowski, the lead author of the Brown study, whichappears in the July issue of the journal Pediatrics. "Cocaine-exposedinfants were more jittery, had more muscle tension, and were harder to movebecause they were stiff." Some cocaine-exposed infants were also drowsie...Tacrolimus Stops Rejection Of Kidney Transplants
...n following a kidney transplant," said the paper's lead author transplant surgeon E. Steve Woodle, M.D. , from the University of Chicago Medical Center. "Since uncontrolled rejection remains a primary cause of organ loss, this is a significant advance for our patients," he added. Although about half of k...Partial Liquid Breathing Improves Lung Function, Chances of Survival in Sick Preemies
... Buffalo. Results of the trial are reported in the lead article in this week's issue of the New England Journal of Medicine. Respiratory distress syndrome, the leading cause of death in premature infants, develops because the lungs of these tiny babies have yet to secrete surfactant, the substance that p...Raising The Retirement Age In The United States Could Save Billions In Social Security Payments
...e normal retirement age in the United States could lead to otherchanges, Manton added. Workers could be encouraged to take leaves from careersin mid-life to be retrained or to return to college. "That may becomea necessity, if the rate of technological change is rapid enough,"he said. And the federal gov...Program Provides Treatment For Prison-Released HIV-Positive Women
...rison, they may also bereducing the behaviors that lead to drug use and prostitution." Vigilante also operates a storefront clinic that provides medical care andsubstance-abuse treatment to HIV-negative women at high risk of contracting thevirus. He and Flanigan run a program that helps children of inca...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
SAN FRANCISCO -- In research that could lead to better drug design,a Duke University bioorganic chemist is exploiting the differences betweentwo forms of water to probe how proteins' shapes control the way they bindwith other molecules. Such binding reactions, which occur constantly in wa...Researchers Gain Insights Into Drugs Used For Manic-Depression
...f depression followed by episodes of mania thatmay lead to disastrous decisions and actions. As many as one in fivemanic-depressives commits suicide. Until recently, lithium was the best medication available for thedisease, but because of undesirable side effects many people discontinueits use. I...TB Prophylaxis Unnecessary In HIV-Infected People With Anergy, Study Suggests
...ople in this group is probably notwarranted," says lead author Fred M. Gordin, M.D., of the Veteran AffairsMedical Center in Washington, D.C. "It would be more appropriate to reserve INHpreventive therapy for HIV-infected persons who have a prior history of apositive TB skin test or who have been in rece...3D Ultrasound Gives Better View Of Brain's Arteries
...ity. According to Dr. Andreas Delcker, the lead researcher, reliability andreproducibility were especially valuable because patients in the study underwentmore than one imaging examination. While techniques like cerebral angiography remain the diagnostic goldstandard, ultrasound is being a...Duke Obtains FDA Designation For Pompe Disease Therapy
...ct FDA-approved clinical criteria. Chen, who will lead the clinical trial, anticipates that recombinantenzyme injected into infants will be taken up by their muscle cells andrestore normal glycogen levels. This treatment, known as an enzyme replacementtherapy, would be required for the rest of these pati...Study Demonstrates The Benefits Of Mammography In Women Under 50
... Presenting the study was Dr. Jeffrey Bradley, lead study author from theUniversity of Chicago. Dr. Bradley's study focused on 869 women who were both under 50 and over50. He said the study indicated that screening mammography was effective forall the age groups represented. "The tumors that...Common Drug-Capsule Coating Not As Inert As Previously Thought
... trigger an unwantedbiological response that would lead to rejection." One of the current problems in the design of biomaterials is that thereis no direct correlation between a material's properties and its biocompatibility,Leckband said. "Because of its apparent low toxicity and apparentinertness, PEG ......versial benefits are unlikely to be helpful." The lead author, David J. Doukas , M.D., is an associate professor in the U-M Department of Family Practice and associate director for clinical bioethics in the U-M Program in Society and Medicine . Co-authors are Michael Fetters , M.D., and Mack Ruffi...