Substance from Grapefruit Juice May Make Medications Safer
... between individuals, which, in turn, affect their metabolism of drugs. Thus, a dose of a drug that may be effective for one individual can be toxic to another. Addition of the active substance in grapefruit juice to a medication could produce a drug for which a standard dosage would be equally effective in e...New Approach To Multidrug Resistance
...ple, those involved in cellstructure or basic food metabolism -- are less vulnerable to damage than genesinduced in response to external signals -- such as hormone fluctuations or anincursion of foreign chemicals. Because the gene for P-glycoprotein isinducible, activated by cues from its environment, investig...Compound In Meat Prevents Diabetes, Study Suggests
...n adjunct assistant professor of endocrinology and metabolism at the Indiana University School of Medicine. A provisional patent on using CLA to treat diabetes has been issued to Purdue and Penn State. According to Belury, CLA is a polyunsaturated fat found in meats and cheeses, and in lesser amounts in milk, y...More Bad News For Fast Food Fans
... and Kenneth R. Feingold, MD, SFVAMC department of metabolism and UCSFprofessor in residence. The research was funded by the U.S. Department ofVeterans Affairs and the Pacific Vascular Research Foundation....Discarded Treatment For Heart Attacks May Yet Prove To Be A Life-Saver
...ompletelydifferent, in that it alters heart muscle metabolism and biochemistry to protectthe region of the heart deprived of oxygen by a heart attack." The 407 people in the trial included 252 individuals treated with eithera clot-dissolving drug or a balloon-tipped catheter inserted into the vessels to...Antabuse May Inhibit Fatal Reaction To Anesthetic
...curshas been incompletely understood. Drug metabolism is the process by which our bodies transform andel...harasch has identified the role of p450 2E1 in the metabolism ofseveral other volatile anesthetics. The major component in Tylenol, forinstance, is also metaboliz......their studies to otherCYP enzymes involved in drug metabolism with Reginald Frye, Pharm.D., Ph.D., ofthe University of Pittsburgh School of Pharmacy....Weight loss is associated with slower metabolism
...merican Journal of Clinical Nutrition. Thisslower metabolism may explain why dieters have difficulty in keeping weight off....Summer swimsuit research flash: thigh-reducing creams don't work
...lline and its potential to reduce fat byincreasing metabolism showed it was not effective enough in humans to continuestudying, Marks said....Hopkins study shows combined hormone therapy increases muscle, decreases fat in postmenopausal women
...udy and an associate professor ofendocrinology and metabolism at Hopkins, led researchers comparing the effectsof estrogen supplements versus combined testosterone/estrogen supplements. Agroup of 40 postmenopausal women took an estrogen supplement for three monthsand estrogen plus androgen for the next four mo...Female hormones don't cause overeating and weight gain
...r contraceptive hormones, youlower a woman's basal metabolism and she will gain weight," Pelkman says. "Wesaw no dramatic increase in calorie intake and didn't see a dampening of thenumber of calories the women burned. There were no changes in food preferencesor diet composition either." She adds, "The...UK researcher develops nicotinic drugs with R.J. Reynolds
...s coworkershave completed extensive studies on the metabolism and pharmacokinetics ofnicotine in and around the brain. Collaborating with colleague Linda Dwoskin, Ph.D., UK professor of pharmaceutical sciences, Crooks has investigated the pharmacological actions ofseveral nicotine metabolites and nico...Obesity drugs not a quick fix for achieving weight loss
... nine obesity drugs to date. Eightwork by altering metabolism in the brain to suppress appetite and keep patientsfrom feeling the need to eat. The ninth and newest, called Xenical (orlistat),prevents absorption of fat from the gastrointestinal tract. When compared withstudy patients who were given inactive plac......proteins that act as regulators inimmune function, metabolism and sleep. Vgontzas and his colleagues' paper titled, "Circadian Interleukin-6Secretion and Quantity and Depth of Sleep," is published in the August issue ofThe Journal of Clinical Endocrinology and Metabolism. Vgontzas and his team s......ctateactivation. Lactate is a by-product of energy metabolism produced by neuronswhen the brain is activated. Most, but not all, of this brain activity tookplace in the left anterior, or frontal, lobe of the brain, which is known to beone of the centers for expressive language function. "The dyslexics w...Raise eggs' vitamin D3 content sevenfold by adding more vitamin D to chicken feed
... systematically follow vitamin Dconcentrations and metabolism in eggs as these factors are affected by feed withdifferent vitamin D levels," said Mattila. The work was done on 54 hens over six weeks, 90 percent of them in laying modeat the study's beginning and all them 30 weeks old. They were divided intothre...Extract from traditional Chinese herb enhances recovery in stressed cells
...highly reactivecompounds that are generated during metabolism and which contribute to thenormal wear and tear of the cell. A rapid buildup of free radicals in cells may be an underlying cause of death incardiac arrest patients who quickly regain a pulse. "Restoring the regular heart beat in cardiac arrest pati...Sleep debt affects metabolic functions
...of sleep debt has a harmful impact on carbohydrate metabolism andendocrine function," write Karine Spiegel, PhD, and colleagues in the October23, 1999 issue of The Lancet, a leading British medical journal. These effectsare commonly seen as part of the normal aging process, and persistent sleep debtmay, theref......, partial sleep loss on the body by evaluating the metabolism and hormonesecretion of subjects subjected to sleep restriction and after sleeprecovery. "We found that the metabolic and endocrine changes resulting from a significantsleep debt mimic many of the hallmarks of aging," said <AHREF="http://www.ccp.......ty of California at San Francisco report that slow metabolism of nicotine due to CYP2A6 defects may explain why Chinese-Americans smoke less than whites. (Oral presentations) Sweet News for Sickle Cell Anemia Sufferers The artificial sweetener aspartame has been reported to be effective in counteracting th...