Tag: "myelogenous" at medical news

Plant derivative attacks the roots of leukemia

...ide would act on the most primitive types of acute myelogenous leukemia cells, chronic myelogenous leukemia cells and normal cells. In laboratory experiments, they also compared how human leukemia st...

Study finds new designer drug is potent treatment for chronic myelogenous leukemia

... a potent and highly selective therapy for chronic myelogenous leukemia (CML) may ultimately be more effective than Gleevec, the current standard of care. The researchers report in the February issue of Cancer Cell that the new compound, AMN107, is about 20 times more potent than Gleevec and is effective in trea...

Study finds new designer drug is potent treatment for chronic myelogenous leukemia

...erland have created a targeted therapy for chronic myelogenous leukemia (CML) that may ultimately be more effective than Gleevec, the current frontline treatment. The researchers report in the February issue of Cancer Cell that the new compound, AMN107, is about 20 times more potent than Gleevec and is effective...

New leukemia drug shows promise in overriding all Gleevec resistance

...ially treat all forms of Gleevec-resistant chronic myelogenous leukemia (CML). Their work is published in this week's early edition of Proceedings of the National Academy of Sciences. According to lead researcher, Prem Reddy, Ph.D., professor of biochemistry and Director of the Fels Institute for Cancer Resear...

Kinder, gentler procedure gives superior results for stem cell transplants

...studies targeted at sickle cell anemia and chronic myelogenous leukemia to explore the potential for successful transplants in children with these disorders....

Peptide vaccine can produce complete remission in myeloid leukemia patients

...these patients had either active or relapsed acute myelogenous leukemia (AML) or refractory chronic myelogenous leukemia (CML) - forms of leukemia in which there is a dangerous accumulation of immature cells in t...

Study shows haploidentical natural killer cells may provide hope for some patients with AML

...wed hope for some patients who have advanced acute myelogenous leukemia (AML), a highly fatal cancer of the bone marrow, that has become resistant to standard treatment with chemotherapy. Natural killer cells are part of the body's immune system. The cells play an important role in defending the body against ...

Farnesyl transferase inhibitor can help patients at high-risk for developing AML

...a pre-leukemic disorder that can progress to acute myelogenous leukemia (AML), according to a study presented at the annual meeting of the American Society of Hematology (ASH). The drug R115777 (Zarnestra) (tipifarnib) produced responses that ranged from complete responses to improvement in blood counts in about...

Imatinib (Gleevec) has activity in AIDS-related Kaposi's sarcoma

...iginally shown to be effective in treating chronic myelogenous leukemia and gastrointestinal stromal tumors. This...e for the growth of other cancers, such as chronic myelogenous leukemia, gastrointestinal stromal tumors (GIST), and bone sarcomas of the head and neck. Given that...

Obesity linked to another cancer - leukemia in older women

...ld more than double an older woman's risk of acute myelogenous leukemia (AML), an often fatal cancer of the bone marrow and blood. The results of the study are published in the November issue of Cancer Epidemiology, Biomarkers and Prevention journal. Other studies have shown overweight and obesity are risk facto...

Gene-silencing technique offers new way to fight drug-resistant leukemia

... a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines. The challenge of developing these medicines, which spare normal cells because they are designed to kill only cancer cells, ha...

$5 million grant awarded to U.VA health system targets leukemia drug development, creates new jobs

... the targeted chemotherapy drug Gleevec forchronic myelogenous leukemia as a powerful example of the potential of...lation of blood cells. The disease is divided into myelogenous and lymphocytic leukemia, each of which can be acute or chronic. About 33,440 new cases of leukemia ...

Chemists honor 'Heroes' for biotechnology achievements in health

... age of 60, who have suffered a relapse from acute myelogenous leukemia (AML). When combined with standard chemotherapy, the drug works more effectively than either therapy alone. Mylotarg has substantially fewer side effects than standard chemotherapy. The 3M award winners: John F. Gerster, Ph.D., retired ...

Higher doses of cancer drug imatinib proven effective and safe

...mined 114 patients recently diagnosed with chronic myelogenous leukemia (CML), a cancer that is diagnosed in about 4,600 people in the U.S. every year. CML is classified into three stages: chronic, accelerated, and blastic. Study participants were all in chronic phase, the least severe of the three. The current ...

More than $34 Million in SPORE Grants

...tment of several leukemia types, including chronic myelogenous leukemia (CML). In one of the fastest reviews ever...uals with other forms of leukemia, including acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL), and myelo...

Molecular test proves to be effective in measuring remission and relapse after cancer treatment

...onitor the disease status of patients with chronic myelogenous leukemia after treatment with a bone-marrow or stem-cell transplant, the molecular test enables physicians to respond quickly if there are signs of relapse with treatment decisions that has ultimately saved lives. In a study published in the Oct. 9 i...

Imatinib shows early promise against Ewings sarcoma

...duced high response rates in patients with chronic myelogenous leukemia and gastrointestinal stromal tumors. Both cancers are associated with the overactivation of a specific tyrosine kinase. In Ewing's sarcoma, overactivation of the c-kit receptor tyrosine kinase contributes to tumor growth and tumor cell proli...

Fred Hutchinson oversees two grants of nearly $8 million to develop blood test for breast cancer

...nding for prostate cancer, ovarian cancer, chronic myelogenous leukemia, neurofibromatosis and tuberous sclerosis research. Other institutions that received DoD funding this year to establish a Breast Cancer Center of Excellence were M.D. Anderson Cancer Center, Houston, Texas; Barbara Ann Karmanos Cancer Instit...

Fred Hutchinson Research Center awarded $7 million grant

...ec (STI-571) is an effective treatment for chronic myelogenous leukemia (CML). Gleevec, manufactured by Novartis, was approved by the U.S. Food and Drug Administration (FDA) last year and is now considered the most effective front line therapy for newly diagnosed CML patients. SCOR awards are chosen following a...

Maxim Phase II Clinical Trial Highlights Substantial Increase In Leukemia-FreeSurvival For Acute Myelogenous Leukemia Patients

...its leaddrug Maxamine® in patients with acute myelogenous leukemia (AML). Theresults from the trial suggest...rope and Australiafor malignant melanoma and acute myelogenous leukemia. Phase II trials ofMaxamine Therapy are ongoing or planned for other cancer indications su...

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