'Bathtub' Equation Aids Diabetes Research
...ere formed and howthey died. The model predicted a phase of cell death in young, normalgrowing rats. Further research proved the prediction to be true. "Just thinking about the numbers and using some basic principles allowed usto learn something of the physiology that no one ever considered, and thatno one...Cardiovascular Disease Epidemic Threatens Developing Countries, Global Economy
... epidemiologicaltransition, but whether the middle phase of the transition can be abbreviated socountries can arrive more quickly at the later stage when deaths occur at olderages. With consumption of tobacco rising in developing countries, even as itfalls in industrialized nations, tobacco contro...Research Trial To Test New Drug For Diabetic Neuropathy
...e if the drug is working," says Simmons. "If this phase two trial shows promising results regarding nerve... conduction velocities, we would likely move to a phase three trial. That would mean not only looking for improved nerve conduction but also to see if the ...Identification Of Brain Areas Could Help Eliminate Side Effects Of Pain Medication
...ion. Lydic explains that REM sleep is the dreaming phase of sleep and is essential for feeling rested. Everyone has REM sleep each night, even if we do not remember our dreams. REM sleep occurs about every 90 minutes and lasts for about 20 minutes. "We think this is a very exciting discovery. We are ......f for patients with advanced prostate cancer. The phase III clinical trial, designed to test the drug's efficacy, involved 458patients, with an average age of 68, at 76 medical centers in the United Statesand Canada. In the study, the researchers reported that a significantly greater number ofpatients re......herapy," concluded Dr. Belani. The ongoing phase III studies with the paclitaxel/carboplatin regimenbeing performed by the SWOG, ECOG, CALGB will further substantiate the resultsof this regimen with NSCLC. Lung cancer is one the most common cancers in the United States,representing about 15...New Radiation Procedure Targets Liver Malignancies
...ue of the Journal of Clinical Oncology . The next phase of the research involves further increasing the radiation dose in an additional group of patients (because the current formula has been found to over-estimate the risk of complications) and studying how much this regimen improves tumor control....Efficacy And Safety Of Oral Phentolamine (Vasomax) For The Treatment Of MinimalErectile Dysfunction
...w drug for minimalerectile dysfunction. The first phase was designed as a placebo-controlled,parallel grou... mild to moderate erectiledysfunction. The second phase was a placebo-controlled, crossover design offixed dose 40 mg oral phentolamine versus placebo. Out...Nitrosamines Play Important Role In Cancer Linked To Smoking
...ht adds. Many agents havebeen tested in mice, and phase I clinical trials for the leading candidate, anisothiocyanate called PEITC, are being initiated. # # # # Researcher contact: Dr. Stephen S. Hecht, 612-624-7604 (phone); 612-626-5135(fax); hecht002@gold.tc.umn.edu (email); or Coleen Southwel...Crystal Structure Of gp120 Reveals HIV In Action
...faring no better than those whoreceived placebo. A phase III trial of another variation on the gp120 vaccinetheme received the Food and Drug Administration's go-ahead in early June. Futuretrials could target other portions of the molecules that the new crystalstructure reveals to be crucial to infection. ......much more frequently. The findings of the phase III clinical trial appear in the June 18 issueof the New England Journal of Medicine. The research was funded in part by theDuke Comprehensive Cancer Center. "The improvement for these patients was significant enough that this nowconstitutes...Timing Of Breast Cancer Surgery Doesn't Appear To Influence Survival Anymore
... that timing breast cancer surgery to a particular phase ofthe menstrual cycle influences subsequent survival. "This is an enormously controversial subject," says Dr. Harlap. "Ournew data has shown that the timing of surgery influenced survival for womendiagnosed with breast cancer in the late ...Scientists Report Cancer Fighting Drug As Possible Treatment For Multiple Sclerosis
A drug currently undergoing phase III clinical trials for certain types ofcancer may have potential benefit for the treatment of multiple sclerosis (MS),report researchers from The Rockefeller University, Albert Einstein College ofMedicine (AECOM), British Biotechnology Pharmaceutica...New Survey Finds Physicians Seek More Clarity In MS Diagnosis And Management
...nt of neurologists believe that thereis a distinct phase between RRMS and SPMS. However, only two percent ...eled, neurologists are beginning to recognize this phase of thedisease as being distinct. The University of Maryland-sponsored, consensus conference...World's First Producer To Repair Brain Damage From Stroke
...adyoccurred in the stroke patient's brain. If the phase I trial proves successful,the next step would be a...ron-transplant study is a single-site FDA approved phase I trial. The primary goals of a phase I trial are to ensure the safety and tolerance ofthe therapy i...Three INEEL Inventions Win International Recognition
...RSP Toolingtechnology. Participants in the initial phase of a two-year collaborativedevelopment project include: Baxter Healthcare Corp., Diemakers, Ford Motor Co.,Hach Plastics, Johnson Controls, LaserFare, Lockheed Martin AcronauticalSystems, Northwest Mettech Corp., Proctor & Gamble, and United Technolo...Novel Therapy To Treat Lung Cancer Patients Enrolling Patients At UCSF Cancer Center
...al cancers combined. The new UCSF study will be a phase II clinical trial, the stage of testingdesigned to determine a drug's effectiveness. To qualify for the anti-VEGFantibody trial at UCSF/Mount Zion, part of UCSF Stanford Health Care, patientsmust have advanced lung cancer and have had no previous c...Novel Therapy To Treat Lung Cancer Patients Enrolling Patients At UCSF Cancer Center
...withchemotherapy infusions. This is a multicenter, phase III study, the stage of atrial designed to determine the drug1s effectiveness. To quality for the trial at UCSF/Mount Zion, part of UCSF Stanford Health Care,patients must have advanced non-small cell lung cancer, a recurrence of thedisease following......ial Revascularization (PTMR), which ispresently in phase II clinical trials at Cedars-Sinai Medical Center. Interviews: Norman Lepor, M.D., Principal Investigator, and patients DELICATE SKULL BASE BRAIN SURGERY CAN GIVE PATIENTS WITH DEBILITATING FACIALPAIN A NEW LEASE ON LIFE Universally acknowledged as......ncisco and 11 other academic centers. The initial phase included 2,027postmenopausal women between the age...spine fractures, as detected by X-ray. The second phase of FITincluded 4,432 women with thin bones but no previous spine fractures. More than 200 mi...