Tag: "pioglitazone" at medical news
Penn study shows how next-generation diabetic drugs could work more selectively
... TZDs such as rosiglitazone maleate (Avandia) and pioglitazone
hydrochloride (Actos) help to maintain diabetics' blood-sugar levels. In fat cells, TZDs turn on a small set of genes, which aren't normally turned on, by targeting the receptor PPAR. To tease out how the medications work specifically, the investig...
Insulin resistance intervention after stroke focus of $33 million grant
...oke. The participants will be randomly assigned to pioglitazone
or placebo in addition to their usual therapy. "We...ave designed the trial to test the hypothesis that pioglitazone
will reduce the risk of recurrent stroke or heart attack by 20 percent during 4 years of therapy," s...
Pioglitazone shown to reverse thickening of carotid artery wall
...essions 2004 proceedings, have shown that the drug pioglitazone
(ACTOS, Takeda) significantly reduced the thicknes...ter 173 patients received oral therapy with either pioglitazone
(45 mg/day) or glimepiride (1-6 mg/day). Baseline carotid IMT was 0.949 0.149mm in the pioglitazon...
Pioglitazone HCI shown to lower blood pressure in hypertensive patients with type 2 diabetes
...w that treatment with the oral anti-diabetic agent pioglitazone
HCl in people with type 2 diabetes has beneficial ... type 2 diabetes, all patients received open-label pioglitazone
(30 mg/day) for 16 weeks. Hypertension was classified according to current National Institutes of H...
American Heart Association consensus statement
...e. TZD agents rosiglitizone maleate (Avandia) and pioglitazone
hydrochloride (Actos) help doctors manage patients' glucose (blood sugar) levels and may even modify other heart disease risk factors such as high blood pressure, high cholesterol and inflammation, said Richard W. Nesto, M.D., chair of the department...
Two commonly prescribed diabetes drugs may cause heart failure and fluid buildup
...edings, the researchers report that the oral drugs pioglitazone
and rosiglitazone can cause or exacerbate heart fa...s developed after one to 16 months of therapy with pioglitazone
or rosiglitazone. In three patients, doses of these medications were increased three weeks to three ...
Annals of Internal Medicine, tip sheet, March 19, 2002
...ver returned to normal. The authors suspected that pioglitazone
caused the liver damage, especially after tests for other causes of liver damage were negative. They were suspicious because a similar drug, troglitazone, was associated with severe liver damage and was withdrawn from the market. The authors recommen...