Existing therapies applied to new use in broader spectrum of cancer care
...latches onto B12 receptors and delivers a knockout punch to the tumor cell. "Tumor cells hungrily ingest the modified Vitamin B12, just as they do the natural micronutrient," Bauer said. Inside the tumor cell, however, the nitric oxide component of the targeted drug is released, t...Making smart drugs that deliver the right kind of punch
... punching holes in them." That wasn't the kind of punch the researchers wanted to deliver, so they tried tinkering with the dendrimers to see if they could prevent the damage. "Dendrimers usually have a charge, and so do cell membranes," Mecke said. "It's the interaction between those charges that causes ...Microneedles: Report describes progress in new technology for painless drug delivery
...s produced arrays of up to 400 needles designed to punch holes in the outer layer of skin to increase its permeability to small molecules applied with patches. That work has broadened to include both solid and hollow microneedles in a broad range of shapes with feature sizes from one to 1,000 microns. Pra...Mayo Clinic study shows melatonin helps alleviate violent sleep disorder symptoms
...eams decreases, and they have far less tendency to punch and kick. Therefore, the potential for injury to themselves and their bed partners is reduced." Only five, or 36 percent, of the patients who took melatonin for RBD experienced infrequent, minor side effects such as headaches or sleepiness in the mor...Appreciation of humor doesn't change with age
... or head trauma -- not only had difficulty getting punch lines, but preferred slapstick humor. In this curr...the ability of the responder to select appropriate punch lines to jokes or provide appropriate logical reasoning as to why a stimulus is humorous. Humor 'app...Analysis finds drug improves odds of complete stroke recovery
... Researchers found that citicoline packs a one-two punch against stroke, blocking this chain reaction, while also facilitating the repair of damaged brain cells. Each year, about 600,000 Americans have a new or recurrent stroke, according to the American Heart Association. Ischemic strokes are the most c...New cold treatment developed at the University of Virginia
...w combination drug therapy that delivers a one-two punch to knock out colds. In study results reported in the current on-line issue of The Journal of Infectious Diseases, subjects used a new combination of drugs that stopped their viral infection and reduced symptoms by as much as 73 percent with no seriou...Research at Great Lakes meeting shows more vitamin C in organic oranges than conventional oranges
.... Clark said the reason for the added nutritional punch isn't clear, but "we speculate that with conventional oranges, (farmers) use nitrogen fertilizers that cause an uptake of more water, so it sort of dilutes the orange. You get a great big orange but it is full of water and doesn't have as much nutrit...Molecular 'nanogenerator' developed that can target cancer cells and destroy them
...cer cell will be destroyed. You get four times the punch from one atom, Dr. Scheinberg said. Targeting the generator to the inside of the cancer cells also increases the treatments effectiveness. If the atom is sitting on the outside of the cell, the alpha particle can travel in any direction, and it kills...Virginia Tech students discoveries can help prevent water-borne diseases
...iltration, Edwards says, and a burp of bubbles can punch holes in filterstiny holes, but large enough to le...addition to studying why bubbles form and how they punch holes in treatment plant filters, Scardina has made some discoveries. Air bubbles can interfere with...Scientific symposium focuses on nutritional beverages, August 26-28
...rage that delivers up to 14 times more antioxidant punch than apple, orange and grape juices. (The paper on this research, AGFD 35, will be presented at 11:20 a.m., Monday, August 27, at McCormick Place South, Room S504D, Level 5.) #...Cognitive neuroscience takes on alcohol
...y have "a bit too much to drink" and end up in the punch bowl. Some of this behavior could be due to a brain-based lack of inhibition because of alcohol, but some of it could be due to an intentional lack of control while drinking. A study in the January issue of Alcoholism: Clinical & Experimental Rese......er research is needed, it appears that the one-two punch of RT and AST may be a more effective treatment in the battle against both advanced-stage and early-stage prostate cancer," added Dr. D'Amico. The 1,586 study participants were categorized using a combination of their PSA levels, biopsy Gleason sco...Supplements that target fat loss … metals that protect themselves …
...gentler aspirin. A new gasoline additive packs the punch of MTBE without the environmental threat. These ar...ust 22 New form of aspirin delivers therapeutic punch without side effects - A new form of aspirin that could eliminate stomach irritation and other unwa...People With Brain Injury To Frontal Lobe Don't Get Punch Lines -- Prefer Slapstick Humor!
...ight frontal lobe of thebrain have trouble getting punch lines and show a preference for slapstickhumor. Th... Individuals with right frontal damage chose wrong punch lines towritten jokes and did not smile or laugh as much at funny cartoons or verbaljokes. They show...Study Shows Potential For Quelling AIDS Nerve Pain
...in the injury -- something not done before. With a punch biopsy, a relatively painless technique little-used in neurologybut common in dermatology, they removed small samples of the outer layers ofskin. Under the microscope, the researchers found far fewer of the tiniestsensory nerves in the epidermis tha...Snipping Inflammation In The Bud; New Agents May Provide Relief
... new family of compoundsthat packs a novel one-two punch that effectively inhibits the cellularprocesses that cause us pain. Inflammation is the body's response to irritation, infection or injury. Itbegins at the level of the cell when, in response to an injury or irritation,white blood cells in the bloods...Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
...n University Oncology Group had developed aone-two punch of paclitaxel and radiation that was effective against certainlung tumors, an approach that is now used worldwide. Cancers of the lung,stomach and pancreas often share a genetic mutation, labeled p53, that thwartsstandard chemotherapy and radiation t...