Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...esearchers around the country theorize that leptin remains elevated because the fat cells neverreceive its "slimming" signal. In studying the leptin loop, Duke researchers discovered they could applya hormone -- a synthetic form of noradrenaline -- directly onto the surface of fat cells,essentially bypassi...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...y imaging agents, but he realizes a lotof research remains to be done. "We've just demonstrated that we have the capability to dothis, so it's opened up a frontier. We've opened the door, but wehaven't taken too many steps yet." In fact, all of the preliminary research has been done usingrhenium complexes in...Tacrolimus Stops Rejection Of Kidney Transplants
...cago Medical Center. "Since uncontrolled rejection remains a primary cause of organ loss, this is a significant advance for our patients," he added. Although about half of kidney transplant patients will experience at least one episode of rejection, a temporary boost in their medications-increased doses of c...ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
... by partial restoration of the immuneresponse. It remains to be seen after further treatment, saysDr. Lederman, if prolonged virus suppression results in greaterrestoration of immune function. "ACTG 315 indicates the valueof initiating potent antiretroviral therapy early before significantloss of immune fun...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...nges inprotein-water and ligand-water interactions remains "one of the mostdaunting barriers to predicting how ligands bind to their protein receptors,"he said. Toone and his students were able to separate out water's involvementby using a technique pioneered in the 1950s by another professor now atDuk...Milk Extract May Heal Wounds And Smooth Wrinkles
...ling extract from the left-overliquid (whey) which remains when milk is turned into cheese. They say 1,000litres of whey yields only about 30 grams of the precious powder. The secret process for extracting the powder has been patented, and apilot plant capable of processing some 2,000 litres of whey a day h...Targeted Protein Toxin Effective Against Persistent Brain Tumors
... While these resultsare promising, much more work remains before the drug may be ready for marketapproval. In a related study in the same issue of Nature Medicine,(2) NINDS investigatorsled by Dr. Oldfield and colleagues from the National Cancer Institute and theNational Human Genome Research Institute re...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...nces have come as funding todevelop new treatments remains limited. Thus, the research support provided by Targon will enable our scientists to pursue pathways to new treatments that might not have otherwise been possible." According to Colvin, examples of promising new approaches include"antiangioge...X-ray Microscope Designed To Study Jet Engine Components Now Probes Tooth Dentin
... polymer bonding process works bestwhen the dentin remains moist. In the bonding process the liquid fillingpenetrates moist dentin more easily than drier dentin -- much as a moist spongemore quickly absorbs water than a dried sponge, Sally Marshall explains. In the next stage of the study, the researc...Preventing Stroke: The Choice Between Aspirin And Warfarin
...npatients is a significant predictor of stroke, it remains to be seen whetherthese patients should take aspirin or warfarin. The final treatment decisionshould be made between the physician and the patient after considering theindividual's risk for stroke, benefits from treatment, and personal preferences. ...Area of Research Outlined For Promising New Cancer Drugs
...et been tested in humans, and the medicalcommunity remains cautious. Both angiostatin and endostatin evidently interfere with the tumors'ability to synthesize new capillaries from pre-existing blood vessels, a processcalled angiogenesis. Essentially, the tumors were starved when the drugs wereadmini......of Societies in Transition, although the geography remains the same, the role for the WHO has completely altered. The author notes in this week's BMJ that many people do not realise that the European region of WHO includes the entire former Soviet Union, with member states such as Tajikistan, on the Afghan b...Intervention can help reduce risky sexual behavior, according to results published in Science
...which to track HIV eradication;an overview of what remains to be done in the race to defeat HIV; and Thailand'ssuccesses and difficulties in that nation's response to HIV. Please note: A related news conference will take place on Thursday, 18 June at 1p.m. on the main campus of NIH, Wilson Hall, Building 1,...Drug Combination Including New "Super Aspirin" Drug Cuts Risk Of Death Or Second Heart Attack
...ed aspirin. "The additive role of heparin remains uncertain, but appears morefavorable with low-dose lamifiban," Moliterno says. After 30 days there was a minor difference in the number of deaths or secondheart attacks among the low-dose lamifiban, high-dose lamifiban, and standardgroups. However, ...Novel Therapy To Treat Lung Cancer Patients Enrolling Patients At UCSF Cancer Center
...use the prognosis for patients with advanced NSCLC remains poor, thedevelopment of new treatments for the disease is highly desirable. Lung cancer is the leading cause of cancer death in the United States andworldwide. Approximately 900,000 people worldwide are diagnosed with lungcancer each year, according......PA) -- How the brain works and why it malfunctions remains amystery that drives scientists and physicians to seek answers. A scientifictriumph in this crusade occurred when an advanced brain imaging agent, calledTrodat, was developed at the University of Pennsylvania Medical Center. Thisimaging agent could...University of Kentucky Markey Cancer Center Researchers Awarded Grant To Fight Leukemia Recurrence
...te recent advances in treatment, cancer recurrence remains a long-termproblem. Cancer cells often travel throughout the body, thus, some malignantcells may escape chemical or surgical removal.To tackle this problem, Jordan and Yanelli have devised a method to preventrelapse by allowing the patient's immune ...Candles with lead wicks emit lead into the air
...ldren and the elderly,Nriagu said. "Lead poisoning remains one of the most serious environmental health diseases inthis country and other parts of the world. It affects many organ systems andbiochemical processes with the most serious sequelae often occurring in thecentral nervous, cardiovascular and blood ...Elderly Patients May Be Undertreated For High Cholesterol, Wake Forest Doctor Says
...chives of Internal Medicine. Heart disease remains the leading cause of death for people over 65.Recent evidence suggests that elevated cholesterol levels remain a risk factorfor death from coronary heart disease in the elderly in otherwise good health. "Given the clinical trial evidence for ......matic stress disorder, the researchers say, but it remains unclearwhether the other disorders preceded or followed development of PTSD. Otherresearchers, Boudreaux and his colleagues say, "have found evidence that [these]disorders can possibly develop as secondary reactions to the stress of havingPTSD." ...