Studies Look At Threshold Effect Of Cholesterol-Lowering "Statin" Drugs
...researchers found that the benefits of the popular statin drugs -- shown to sharply reduce heart attack risk...er limit for LDL cholesterol," says Grundy. A new statin trial, the Treating to New Target (TNT) study, should provide the answers concerning lower limit of ...International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
...nters in 19 countries andcompared two doses of two statin drugs -- simvastatin and atorvastatin. Bothdrugs r...e did not expect to see such dramatic effects of a statin on low HDL,nor did we expect to find that there was a differential effect betweensimvastatin and ato......in people with diabetes. Pravastatin is one of the statin class of cholesterol-lowering drugs called HMGCoA inhibitors. Sacks reports that, compared with those in the placebo group, diabetic patientswho received pravastatin had a 25 percent reduction in relative risk of havinganother heart attack. The relat...The American Heart Association Urges Caution On Cholestin
...s have reported that lowering LDL cholesterol with statin drugs isassociated with lower rates of heart attac...ch is why the American HeartAssociation recommends statin drugs for cholesterol-lowering as a second stepafter lifestyle modifications including lowering fat ...Heart Experts Call For Action Against Missed Opportunities To Prevent Heart Disease In Women
...ovascular Society. Amongthe recommendations: A statin or cholesterol-lowering drug should be considered ... as much or even more than menby taking one of the statin drugs. Previous recommendations of the National Cholesterol Education Programsuggest that HR...New biological target identified for cholesterol-lowering drugs
...he first to investigate how the long-term use of a statin drugaffects this inflammatory process, and it adds...n the last 25 years has been thedevelopment of the statin drugs," Braunwald adds. "They've been shown innumerous trials to lower cholesterol and decrease the...Cholesterol lowering in elderly reduces heart disease and strokes
...gh risk for CHD benefitgreatly from treatment with statin drugs. "It is important for older Americans to pay attention to theircholesterol," said NCEP's Cleeman. "Even if you're 70 and feeling fine, you candevelop CHD, so you should take action. "Whether you are old or young, cholesterol co...Novartis receives FDA approval for LESCOL XL 80 mg
...tial to bring the majority of patients who require statin therapy to their treatment goals." For patient...ase delivery form of the drug, availability of the statin to the liver is increased while minimizing the risk of systemic exposure to high drug doses througho......ded in people at risk of vascular disease by using statin drugs to lower blood cholesterol levels irrespect...mmary of major findings Cholesterol-lowering with statin treatment reduces the risk of heart attacks and of strokes by at least one-third, as well as reducin...Stopping statins may cause rebound that triples risk of death
...mm, M.D., one of the study authors. Withdrawal of statin therapy shortly after the onset of symptoms comple...ed to the hospital, 465 patients had been taking a statin drug for six months. Statin therapy was continued in 379 patients and discontinued in 86. After th...Statins may inhibit calcium growth on aortic valve in the elderly
...osure: OBrien has received speaking honoraria from statin manufacturers.)...Genetic 'bar codes' predict effect of statins
...ood levels of CETP before and after treatment with statin drugs. They then compared activity levels of CETP... gene SNPs and haplotype to his or her response to statin therapy (as measured by changes in HDL-C, LDL-C and triglyceride levels). The researchers found that...Statin drugs may increase risk of peripheral neuropathy
...those with a definite diagnosis of neuropathy, the statin users risk of developing neuropathy was 16 times h...l cases of neuropathy were taken into account, the statin users risk of developing neuropathy was four times higher than the control groups risk. Taking stati...High cholesterol and calcification are to blame for aortic valve disease
...ages of the aortic valve disease process. Earlier statin use may prolong the time to severe disease and the need for surgical valve replacement. Statins are drugs that block the formation of cholesterol in the liver and increase the production of the receptors on liver cells that clean the bad cholesterol...Statin drugs lower heart disease risk in postmenopausal women
...LAS, June 4 Treatment with a cholesterol-lowering statin can significantly reduce the risk of heart disease...ecifically at the outcomes of 1,004 women taking a statin drug when they entered the study, as well as 708 who began statin therapy during the trial. They fo......e LDL-cholesterol levels and the outcomes of early statin use, large clinical trials should be conducted to further refine which patients would benefit from this strategy." Currently, physicians routinely prescribe statins to heart attack patients at or shortly after discharge from the hospital if their lev...Cholesterol-lowering drugs should revolutionise treatment of heart attack and stroke
...idence that guidelines should be changed so that a statin is considered for anybody at an increased risk of ... extra 10 million high-risk people were to go onto statin treatment, this would save about 50,000 lives a year-that's a thousand each week. In addition, this ...Heart experts call for urgent action to implement new findings on cholesterol-lowering treatment
...at irrespective of the blood cholesterol level a statin is considered for anybody at increased risk of eit...review of national and international guidelines on statin use by government organisations, such as the National Institute of Clinical Excellence (NICE) in the...Drug to lower cholesterol also slows calcium build-up in arteries
...coronary calcium increased only 8.8 percent during statin treatment, compared to a 25 percent increase without treatment. Progression of calcification was completely stopped in a group of patients in whom the drug reduced low-density lipoprotein (LDL the "bad" cholesterol) to an extremely low level (belo......dural C-reactive protein; and (4) treatment with a statin drug may lower the risk of death after a procedure...se patients should also be strongly considered for statin therapy." Investigators evaluated data on 8,409 patients (average age 65) who had successful cathet...