Tag: "synthetic" at medical news

More evidence of cannabis-induced psychosis

...king cannabis. One subject was given dronabinol, a synthetic THC that has been in medical use in the USA since 1985. The other subject was asked to drink a decoction of natural THC. The authors hypothesise that the effect may have been because the THC had been ingested, rather than inhaled; digesting THC may p...

Suppressing the cells that trigger cat allergy

...g individuals who were allergic to cats with short synthetic peptides based on the major trigger for cat allergy and then measuring the clinical and immunological response to allergen. They found that treatment with the peptides led to the production of a population of T cells that suppressed the proliferation...

Newly discovered pathway might help in design of cancer drugs

...tches on the DNA damage process. He said that the synthetic DNA is very similar to that which is produced when cells are exposed to radiation, with one exception: Greenberg's team's DNA was damaged at only one place on its chain, allowing the researchers to study it and learn about that particular chemical pa...

Marijuana ingredient may stall decline from Alzheimer's

... DC February 17, 2005 -- New research shows that a synthetic analogue of the active component of marijuana may reduce the inflammation and prevent the mental decline associated with Alzheimer's disease. "This research is not only a major step in our understanding [of] how the brain reacts to Alzheimer's diseas...

Stem-cell research hints at better looking cosmetic and reconstructive surgery

...ith stem-cell generated natural tissues instead of synthetic implants. Saline and silicone implants for breast augmentation may rupture, leak, and interfere with breast cancer detection on mammograms. Stem-cell generated natural tissue implants should avoid these problems. Reconstructive surgery to replace tis...

Promising treatments for Huntington's disease identified in UCI study

...ction in Huntington's-engineered mice) and SAHA (a synthetic HDAC inhibitor). In the other test, they combined SAHA with Y-27632 (a protein that blocks polyglutamine aggregation) and geldanamycin (a naturally occurring compound found to relieve Parkinson's-like pathology). "These results provide a proof-of-pr...

Pathogen-mimicking vaccine as strategy for cancer therapy

...rial of a therapeutic cancer vaccine combining the synthetic bacterial DNA sequence, CpG 7909 (ProMune TM , Col...vant and Incomplete Freund's Adjuvant (IFA) with a synthetic peptide (protein fragment) from a melanoma antigen known as Melan-A/MART-1, induced CD8+ T cells tha...

Rice scientist recognized as pioneer in tissue engineering

...y has developed extensive expertise in fabricating synthetic materials with tailored chemistries for specific tissue-engineered repair of orthopaedic injuries. For example, Mikos and his associates have created several novel materials based on fumaric acid, a natural product found in mammalian cell metabolism...

Mice with depression-like behaviors reveal possible source of human depression

...ed their production of glucocorticoid when given a synthetic substitute hormone, the engineered mice showed no change in glucocorticoid levels, demonstrating an impairment in their ability to properly regulate their stress response. The abnormal regulation of glucocorticoid in the engineered mice indicates th...

Rice cartilage experts win $1.5M NIH grant to bioengineer TMJ discs

...esult from TMJ disc displacement, and there are no synthetic materials that can replace a damaged or injured TMJ disc. Rice's new TMJ tissue engineering program aims to develop methods for growing replacement TMJ discs that can be implanted without risk of rejection because they will be grown from a patient...

Brain remapping may be key to recovery from stroke

...earning problem by having 17 healthy adults wear a synthetic glove with fiber-optic cables on their dominant hand. The glove translated hand movements into signals, which were sent to the computer and transformed into the two-dimensional position of a cursor on the computer screen. The subjects were then asked...

Chemoprevention backgrounder: Working for a future of cancer chemoprevention

...hemoprevention" strategy - the use of a natural or synthetic substance to reduce the risk of developing cancer ...le may benefit from combining an NSAID with a safe synthetic retinoid known as fenretinide, which has been shown in an Italian clinical trial to help premenopaus...

Marine sponge leads researchers to immune system regulator

...ed that it was recognized by NKT cells. A purified synthetic version, known as a-GalCer or KRN 7000, is now in phase-2 human clinical trials for several tumor types. One problem with a-GalCer, however, is that it can over-stimulate NKT cells. After a burst of activity and rapid secretion of interferon-gamma,...

Brookhaven Lab and BioSET develop a synthetic peptide that enhances the effect of BMP-2

...ering Technologies, Inc. (BioSET) have developed a synthetic peptide that enhances the effects of a tissue grow...t. The peptide, called B2A2, is one of a series of synthetic analogs of naturally occurring growth factors being developed in the Brookhaven/BioSET collaboration...

New compounds effective against Alzheimer's disease onset and progression

...rn University Feinberg School of Medicine, using a synthetic chemistry platform developed by the Northwestern Drug Discovery Program for the rapid discovery of new potential therapeutic targets. The aminopyridazines are targeted for the potential treatment of certain neurodegenerative diseases that are char...

Northwestern University receives $7.5 million for regenerative medicine

...using on a key component of regenerative medicine: synthetic scaffolds and their interactions with cells. Without the development of effective scaffold technologies Stupp doubts significant progress can be made in regenerative medicine. The six other investigators on the team, who are all affiliated with IBNAM...

Honey could be healthy alternative to high-fructose corn syrup in Halloween candy

...ives, also shows promise as a replacement for some synthetic antioxidants widely used as preservatives in salad dressings and other foods, according to Nicki Engeseth, Ph.D., associate professor of food chemistry at the university. Dark-colored honey, such as buckwheat honey, is generally thought to contain hi...

UMHS researchers help hone use of substance to improve lung function in premature infants

...nd carbon dioxide. Administering animal-derived or synthetic forms of surfactant can help improve lung function...ut new surfactants are on the horizon, including a synthetic version. Donn and Attar see their current study as a first step and stress the need to continuously ...

People are of 'two minds' on moral judgments

...judgment. They wrote that their results "suggest a synthetic view of moral judgment that acknowledges the crucial roles played by both emotion and 'cognition'." Joshua D. Greene, Leigh E. Nystrom, Andrew D. Engell, John M. Darley, and Jonathan D. Cohen: "The Neural Bases of Cognitive Conflict and Control in M...

Sealing corneal incisions with a drop of chemistry, BU researchers develop gel for cataract surgery

...aves; extracts the destroyed lens; then implants a synthetic lens. Currently, the procedure finishes with the surgeon following one of two accepted paths: allowing the incision to seal itself or stitching the incision shut using nylon sutures. Each closing method has its drawbacks. Self-sealing, in which t...

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