Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...ed fat reservesas it does with signaling the brain that the stomach is full -- a discovery that could leadto a new class of drugs that bypass the leptin brain circuit and target the fat cell itsel...AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...auncha multi-pronged attack against HIV, the virus that causes AIDS, and willemploy clinical strategies ne...f Health, two setsof experiments will be conducted that aim to annihilate HIV from infectedpatients as much as possible, and to then rebuild their immune sy...Shark-Liver Substance May Slow Growth Of Brain Tumors
Results of Johns Hopkins animal studies show that a natural shark substance nearly stops the growth of new blood vessels that nourish solid brain tumors. The results suggest that the substance, squalamine, named for the shark ...Study Says Machine Sensors Applicable To Human Ills
...buquerque, N.M. during April 21-24. "We recognize that people are not machines and that this is not aneasy problem," Hansen says. Nevertheless, he adds, "it appearsfrom our experience and ...DNA Imaging to Design Better Drugs
... area of drug-DNA interactions." "One can imagine that the method could be of wide use in thepharmacology...esof DNA -- from 300 to over 100,000 base pairs -- that more closelyresemble the genetic material in the cells of living organisms. Traditional methods tha...Digital Speech Analysis Tests Sobriety
Slurred speech is often a sure sign that someone's been drinking. Now, a Georgia Institute...rough your vocal cords." Preliminary results show that intoxicated speech is marked by jumpychanges in pitch and energy production and unsteady opening and...Use Of Surfectant Therapy Widens Gap In Death Rate Of Black And White Newborns
...y due to the advent ofsurfactant therapy, a liquid that allows babies' lungs to inflate. Afterthe Food and... at Washington University School of Medicine shows that theoverall drop is due exclusively to a reduced number of deaths in prematurewhite infants. After th...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...tracer such as technetiumwith a ligand or compound that can target the tissue or organ ofinterest. For exa...ake it into a sensor by coating it with thepolymer that gives us the selectivity needed to detect theimaging agent in the presence of other compounds in tis...Testosterone May Affect Learning Skills; May Be Put In Tablet Form
...s studying testosterone-replacement therapy report that the primary male sex hormone may affect some learn... with low testosterone, while many studies suggest that estrogen replacement therapy reduces the risk of heart disease and osteoporosis in women after menop...New Colorectal Cancer Treatment Available
...f a large-scale, international, multi-center study that will evaluate the use of the new drug as a first l... preliminary studies at our institution and others that CPT-11 is safe and has activity in some patients when used in a second line setting -- after primary...Emory Doctors Discuss "Killing Heat" In This Week's NEJM
... In addition, the authors site a proactive program that was begun in Memphis after the 1980 heat wave: In early summer, officials track the numbers of persons seen in emergency departments to try to detect any increase in visits due to the heat. The city maintains a 24-hour telephone line to...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
... pain in cancer patients. The researchers believe that the polymer implant could offer an alternative to ...able to meet the needs of a particular patient, so that patients requiring more pain control can get polymers that release more drug, and those with very st...Maternal Exposure To Crack Cocaine Produces Stressed Newborns
...Health, of about 1,400 infants and children. Given that studiesof crack babies in the 1980s produced confl...rchers said. "From this study, we've also learned that cocaine exposure in the womb maynot produce newborns with hemorrhages, lesions and brain damage, as...Discovery Hints At Multitude Of New Targets For Drugs
...drugs andhormones act on steroid hormone receptors that trigger cellular responses. The new view holds that steroid receptors are not merely on-off switches,but are far more complicated molecular "control pan...Alzheimer's disease center seeks patients for new drug studies
...ting propentofylline, an oral drug for Alzheimer's that also may be effective for patients who experience ...funded Alzheimer's Disease Center. "We are hopeful that these new drugs will prove beneficial to at least some of the patients who experience the devastatin...What Makes Tics Tick? Clues Found In Tourette Twins' Caudates
...or carrying out automatic behaviors. They suggest that this dysfunction may underlie the compulsion to act out the sudden movements and vocalizations that characterize Tourette Syndrome, which affects about 100,000 Americans with its full-blown form and u...Tacrolimus Stops Rejection Of Kidney Transplants
...ss in reversing the worst-of-the-worst cases means that tacrolimus has become our preferred treatment for ...of the transplanted kidney. These results indicate that overall, tacrolimus therapy may reduce the 10 to 15 percent of kidneys that are lost to repeated or ...Partial Liquid Breathing Improves Lung Function, Chances of Survival in Sick Preemies
... syndrome in extremely premature infants has shown that the procedure is safe and effective, and improves ...bies have yet to secrete surfactant, the substance that prevents the air sacs from collapsing. Conventional therapy for this condition -- increasing the p...Study Demonstrates Safety & Effectiveness Of Asthma Drug
...cation for treating mild asthma. The results show that the commonly prescribed inhalant drug, albuterol,s...regular medication. The inhalant is a beta-agonist that relaxes smoothmuscles of the airways. It is sold under the brand names of Ventolin andProventil. Th......ty scientists have developed new chemicalcompounds that show promise in fighting malaria, a disease thatki...mpounds use the samemechanism to kill the parasite that causes malaria, but they aremuch less expensive and easier to produce than drugs presentlyavailable....