Epstein-Barr virus protein crucial to its role in blood cancers
...ell cycle for control. Now we can develop targeted therapeutics to disrupt the function of this viral protein." The researchers surmise that the first use of future therapies from these studies will be in lymphoproliferative disease in transplant and immunocompromised patients because this is a clear case of EBV-...Two years after gene therapy treatments, severe angina patients showed prolonged clinical benefit
...ial, VEGF-2 treatment may result in a new class of therapeutics for the treatment of refractory angina." Richard E. Otto, President and CEO of Corautus, stated, "The long-term findings being reported in the Journal of Interventional Cardiology this month are consistent with the one year follow-up results previou...LRRK2 gene mutation causes Parkinson's disease in several families
...vents that cause Parkinson's disease and to target therapeutics to halt its progression."...Johns Hopkins scientists receive presidential medals
...sistant professor of pharmacology and experimental therapeutics the following year. In 1970, by age 31, he had risen to full professor in both departments. In 1980, Snyder was appointed the first University Distinguished Service Professor of Neuroscience, Pharmacology and Psychiatry and director of the Departmen...New test is first step in early detection of Alzheimer's disease
... development that promises early intervention when therapeutics may be most effective -- long before plaques and tangles develop in the brain and dementia sets in. A study by the Northwestern team shows that bio-bar-code amplification (BCA) technology, which was developed at the University, can detect in human ...UGA researchers receive NIH contract to create a stem cell-based drug assay for SMA
... preclinical research and development of candidate therapeutics for treating SMA by late 2007. The UGA team hopes to have the first assay ready in one year. "All the talk surrounding stem cell research has focused on cell therapy," said Steven Stice, one of UGA's Georgia Research Alliance Eminent Scholars and th...Researchers shed light on cancer susceptibility using 'supermice'
...k of developing cancers and may influence the way therapeutics are being developed. Serrano says "I fantasize about a hypothetical drug that moderately increases the activity of p53, p16Ink4a or ARF. This may translate in a big benefit regarding cancer susceptibility." ...Gene-silencing technique offers new way to fight drug-resistant leukemia
...ic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines. The challenge of developing these medicines, which spare normal cells because they are designed to kill only cancer cells, has been complicated by the recognition that resist...Scientists find new clues underlying mood disorders
... developed, according to Jones. "Targeted therapeutics made possible by these new technological approaches offer the dream of 'personalized medicine,' in which knowing each person's genetic make-up can help determine how he or she should be treated," said Prabhakara Choudary, adjunct professor of psychia...News tips from the Journal of Neuroscience
...This is good news for these mice and maybe for the therapeutics of these disorders. 2. FGF and Cortical Laminar Development. Hiroshi Hasegawa, Shizuko Ashigaki,Masako Takamatsu, Rika Suzuki-Migishima, Norihiko Ohbayashi,Nobuyuki Itoh, Shinji. The cortex is made up of ...Media invitation first annual EDCTP Forum
...he clinical development of better and more adapted therapeutics and prophylactics for HIV/AIDS, tuberculosis and malaria, and to build or strengthen research capacity in countries in which these diseases are health priorities. The EDCTP builds upon existing programmes and efforts, especially those of its stakehol...Exercise is key to reversing obesity-related heart risk in children
... S. Woo, M.D., chair and professor of medicine and therapeutics and a consultant cardiologist at The Chinese University of Hong Kong. The researchers studied 54 boys and 28 girls, average age 9.9 years. Based on body mass index (BMI), 28 were deemed overweight and 54 were obese. The study did not include childr...Deleting neural STAT3 protein in mice
...ies, he said, could help in the development of new therapeutics to treat obesity and infertility....Advances in prevention and treatment research hold promise for 'pipeline'
...fections that lead to cervical cancer and targeted therapeutics aimed at breast cancer were examples of research h...ell death, or apoptosis." In comparison to other therapeutics that target steroid receptors to reduce tumor growth, such as the anti-estrogen tamoxifen, the agent...Climara Pro (TM) helps alleviate menopausal hot flashes and night sweats
...apy. Committed to developing novel diagnostics and therapeutics that address unmet medical needs, Berlex, Inc., a ...healthcare and dermatology, as well as specialized therapeutics for life-threatening and disabling diseases in the fields of the central nervous and cardiovascular ...Northwestern receives $10 million for cancer prevention trials
...ern University. Bergan is director of experimental therapeutics at The Robert H. Lurie Comprehensive Cancer Center of Northwestern University. "Through this grant, we can now offer new forms of therapy and hope for those who are at high risk for developing cancer. Our aim is to stop them from ever getting cance...Understanding how lymph nodes respond to infection may redefine how immune system functions
... role of mast cells, comes the opportunity for new therapeutics that could improve disease protection," said Abraham. "It's been known, particularly with allergy and asthma, that mast cells are involved in immune dysfunction," he said. "But their real physiological role is triggering both the innate and adaptive ...Memory-enhancing drugs for elderly may impair high-level brain function
...ory in aged mice and havebeen proposed as possible therapeutics for memory deficits in elderlyhumans. Because aging impairs both hippocampal-dependent and prefrontalmemory function, Dr. Amy F.T. Arnsten, Dr. Ronald S. Duman, and colleaguesfrom Yale University investigated how agents that increase PKA activityinfl...More than $34 Million in SPORE Grants
... translation of tumor suppressor genes into new therapeutics for lung cancer molecular epidemiology of lung ca...of the drug Telomerase as a target for lung cancer therapeutics John D. Minna, M.D., of The University of Texas Southwestern Medical School will again serve as the......tious diseases and the development of diagnostics, therapeutics and vaccines. In addition, through partnerships with other agencies and companies around the world, NIAID has made a significant investment in sequencing pathogen genomes. Researchers have sequenced genomes representative of all bacteria considered b...