Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop
...ptin travels through the bloodstream to the brain, where it targets clustersof neurons in the hypothalamus, a brain structure that regulates food intake and metabolism,among other functions. When leptin binds with receptors on these neurons, it sends asignal to the body to decrease food intake. In addition...Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...brainimaging agents at UC. "You see bright regions where muscle tissueis normal and very dark areas where blood flow is blocked." Heineman is an analytical chemist who also has a great dealof experience dev...Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...g pain management to people in developing nations, where cancer rates are high, but little or no treatment for pain is available. "India produces 80 percent of the world's opiates, yet only a minuscule amount of oral morphine was prescribed to cancer patients last year," says Grossman. "Because of limited...Raising The Retirement Age In The United States Could Save Billions In Social Security Payments
...non. "It's a problem for most developed countries where fertility is dampeningout and older populations are growing rapidly. It's already happened tosome degree in some of the Scandinavian countries." In Japan, a study estimated that 24 percent of the country's populationmight be over age 65 by the year ...A Surgical Semiconductor Laser With More Precision And Power
... semiconductor laser an option for many procedures where other types of lasers are currently used. If you'v...rket scanners, but it limits their use in surgery, where higher power and precision are critical. Thenew laser produces a unified beam no wider than a grain ...UW, Siemens Unveil New Panoramic Ultrasound Imaging Application Using Programmable Technology
...sound imaging applicationinto the clinical setting where it can help in the diagnosis and treatmentof patients. This is a fundamental shift for the ultrasound industry." Programmed to run on the image processor, SieScape imaging dramaticallyincreases the field of view in ultrasound by displaying panoramic ...It Matters Where, In America, You Suffer A Heart Attack
...llow-up, and that the Mountain and Pacific states, where managed care was reputedly more widespread during the study period, rated the best for both the initial hospitalization and up to a year later. "This could upset prevailing views in several ways," said Duke cardiologist Dr. Daniel Mark, who oversa...Drug And Radiation Treatment May Shrink Pancreatic And Gastric Tumors
...mors in several patients had decreased to asize to where they could be removed surgically. "Paclitaxel makes tumors much more sensitive to being killed by radiation,"said Safran, an assistant professor of medicine in the Brown University Schoolof Medicine, based at The Miriam Hospital and at Rhode Island ...Common Carbohydrates May Prove To Be Substitute For Dietary Fiber
...sacat the beginning of the large intestine. Organs where fermentation -- theenzymatic breakdown of foodstuffs by microbes -- occurs actually grew thickerand bigger. Levels of both bifidobacteria and acidity increased. Researchers tested liquid dietary formulas on pigs and got the same resultsas with the r...Duke Study Uses Tiny Temperature Changes To Probe Water-Exclusion At Protein Binding Sites
...eins to devise computer programsthat predict sites where the molecular linkups will occur. "If you gi...cture and the ligand'sstructure they will tell you where the ligand might bind," Toone added. But scientists' problem is they have not yet uncovered al......able levels of false alarms," Barnes said. "That's where you wantto be with a mammogram -- we intend to provide a safety net for theexpert-human analysis that may be susceptible to fatigue factors." The system is not intended to replace radiologists or other medicalor manufacturing professionals, Barnes s...Antimicrobial "Bug Spray" Found In Human Lung Cells
...in both CF patients and in the general population, where infectious lung diseases like tuberculosis kill more than 7 million people every year. "People have always thought that the lungs only attacked infections via the classical immune system--B cells, T cells and other immune cells," says Pete Pedersen, ...Study Injects New Interest In How Vaccines Work
...pular theory was that it created a 'depot effect,' where the aluminum hydroxide particles served as a store...pect to see a lot of lumps and nodules in the spot where people get vaccinated, but there are very few reports of such nodules at the site of vaccination." T...New Drug For Parkinson's Disease Proves Effective, Study Finds
...nter andthe Division of Experimental Therapeutics, where physicians aretrained to design and interpret studies of potential newtreatments to neurodegenerative diseases....Condemnation May Be Driving Circumcised Women From Health Care
... them refugees from Ethiopia, Eritrea and Somalia, where more than 80percent of the women are circumcised. "There are significant medical sequelae and public health ramificationsof female circumcision," the authors write. "As African communities andadvocates grapple with how to stop this practice,...New Ultrasound Technique Is Alternative To Cerebral Angiography
...will not find blockages lower inthe carotid artery where it emerges from the main artery leading from the heart....3D Ultrasound Gives Better View Of Brain's Arteries
... colleagues as well as researchers at Bowman Gray, where Delcker was avisiting professor from January through July, may soon apply the lessons learnedfrom this study of adults to the study of neonatal patients. With those very young patients, ease of obtaining images will helpresearchers who measur...Common Drug-Capsule Coating Not As Inert As Previously Thought
...ications such as implantsand artificial scaffolds, where polymer-coated materials are in contactwith living tissue for extremely long periods of time," Leckband said. "Implicit in such long-term applications is the requirement that thepolymer does not perturb the various protein structures and trigger an u...Planning Researcher Finds Best Neighborhoods Aren't Always Best At Preventing Infant Mortality
... from1979 to 1994 in order to point to those areas where factors likerace, low-income and low-education rat...is not so much on these neighborhoods, nor onthose where higher incomes and higher education rates mean lowinfant mortality, but on those neighborhoods beati......nd to be gotten from seeing a baby that is moving, where you can see its fingers and toes and limbs," says Ella Kazerooni, M.D., assistant professor of radiology at the U-M Medical Center. The research team surveyed 318 pregnant women between the ages of 15 and 44 who were at U-M for their first obs...