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Duke Study Suggests New Class Of Drugs Could Bypass Leptin Loop

...s fat-burning role, Duke researchers haveexplained why leptin causes genetically obese mice to lose more weight than can be accountedfor by appetite suppression alone. They showed that leptin delivers a second signal to thebrain: one that triggers the release of noradrenaline onto the fat cell. Currentl...

Raising The Retirement Age In The United States Could Save Billions In Social Security Payments

...at 62 and 59, has increased. Butpart of the reason why this has occurred is because some retirement programswere set up to provide incentives for early retirement," he said. "Forexample, we've had a period of downsizing and other factors to reduce theemployment rate and to get workers who aren't currentl...

Laser Shown Effective In Patients Who Are Not Candidates For Bypass Surgery Or Angioplasty

... use. "At this point, we do not know exactly why this procedure works,"Lowe said. "We do know that ...re using animal models to better understandexactly why this occurs. It appears that the new growth is somehow relatedto the inflammatory response to the c...

Laser Offers Hope For Heart Patients With No Alternatives

...y. "At this point, we do not know exactly why this procedure works,"he explained. "We do know th...ies. "In the laboratory, we are examining why the capillaries grow intothe channels," Lowe said. "It could be that the addition of certaingrowth ...

The Condom Conundrum--How Are We Going To Teach Safe Behavior If Parents Are Afraid To Talk To Their Children About Sex?

... what our family values about sex are, and explain why we don't want them to have sex too soon. These messages are not contradictory."...

Study Injects New Interest In How Vaccines Work

...shed with interstitial fluid." Hem also questioned why the body did not create a wall around the particle...ism behind this reaction. "The study also explains why aluminum hydroxide adjuvants have such a good safety record," Hem says. "The aluminum hydroxide diss...

Benefits Of Annual Mammography Outweigh Radiation Risks Of Cancer

...the risks, there is no reason I can think of as to why women shouldn’t get this lifesaving screening," Dr. Feig concludes. Earlier this year, the American Cancer Society and the National Cancer Institute both recommended that women 40 and older have regular mammograms....

Physicians' Opinions Influenced By Drug Industry

...ticallysignificant. "This study emphasizes why it is important for physicians to clearlydisclose their financial relationships with manufacturers to ensure that readersand journalists can determine for themselves if there is any potential bias inan author's position," says Detsky. "Editors of jou...

Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs

... thechemicals it recognizes. That may help explain why the blood levels of proteaseinhibitors, despite administration at comparable doses, can vary so widely amongindividual patients, Kim said. "Because HIV attacks the CD4-expressing lymphocytes circulating in thebloodstream, the goal of therapy ...

Bi-Monthly Boosts Of Aspirin Benefit Heart

...is red blood cell-platelet interaction may explain why manyindividuals respond to aspirin in a less than optimal fashion," says Marcus. But in their study, researchers found that a single 300-mg dose ofaspirin could initially "neutralize" the platelet stimulatory activity of thered blood ...

Added Benefit Found For Aspirin Use In Patients With Vessel Disease

...MD. They add that these findingscan partly explain why aspirin has beneficial effects on the rate of heartattacks as proven in other studies. Contact: Dr. Arshed Quyyumi can be reached at (301) 496-5817....

X-ray Microscope Designed To Study Jet Engine Components Now Probes Tooth Dentin

...SF researcherswere the among the first to describe why the polymer bonding process works bestwhen the dentin remains moist. In the bonding process the liquid fillingpenetrates moist dentin more easily than drier dentin -- much as a moist spongemore quickly absorbs water than a dried sponge, Sally Marsha...

Tighter Chemical Binding = Better Meds

...on FKBPwith a series of potential drugs, analyzing why they vary in bindingstrengths and suggesting ways to improve their design -- work thatJorgensen will describe on March 31 at the ACS annual meeting. The Yalechemists also have analyzed drugs that regulate the protein thrombin,which is important for ...

Disagreements Between Clinical Trial Oversight Committees And Physicians Can Affect Drug Trial Results

... us involved in clinical trial design tounderstand why such significant differences between the physicians and thecommittees exist, and to make changes," said Duke cardiologist Dr. KennethMahaffey. "Because physicians treat their patients differently from hospital tohospital, and from country to country...

Warfarin Continues To Be Underused As Stroke Preventive

...Stafford, "we believe there are many other reasons why doctors may not beprescribing this important drug. The use of blood thinners requires frequentblood tests to reduce the small possibility of abnormal bleeding, and bothpatients and physicians might be overly concerned about the risks involved withth...

Fat: It's Not For Breakfast Anymore; Study Finds Fat Linked To Clotting

...LAS, April 10 -- A new study gives one more reason why you may bebetter off beginning the morning with a breakfast of low-fat yogurt, cereal orjuice instead of toast slathered with margarine or a croissant. A study of 91 elderly women reported in this month's Arteriosclerosis,Thrombosis and Vascu...

Most People Cant Identify Stroke Symptoms

...ly as possible after they've hadsymptoms -- that's why it is imperative that people know what these symptoms are. People also need to learn about risk factors in order to prevent a stroke in thefirst place," said Dr. Pancioli. The NINDS has defined the following as symptoms of a stroke: sudden numbness, ...

Drug's Effect On Chromosomes May Explain Second Cancers

...ts inside thecell, and they may help us understand why it causes secondary cancers insome patients.” The study, co-authored by Muller, was published in a recent issue ofthe journal Biochimica et Biophysica Acta . Etoposide is a member of a small class of drugs known as topoisomerase-IIinhibitors....

Dying To Quit: Why We Smoke And How We Stop

... Hard to Give Up We know we shouldn't smoke, so why do we? And why, when we decide to quit, is it seem...ight up to what is considered normal. In assessing why so many of us continue to smoke, Brigham explores the behavioral economics of tobacco use. For many...

Health Risk To "Cigarette Babies" Is Neglected, Duke Scientist Charges

...erve pathways. "Such effects might explain why nicotine is often more viciouslyaddictive in adolescents than it is in adults, and why the adolescent smokerbecomes the lifelong smoker." Slotkin also asserted that the worldwide ...

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