Columbia study finds differences in PSA, PSA density test measurements for Caucasian, Hispanic men
... non-Hispanic Caucasians who had "elevated" PSA or abnormal rectal exam underwent transrectal ultrasound and biopsies between 1996 and 2001 at the Hospital. (Men were classified as Hispanic if they identified themselves that way, or by their surname.) Prior to biopsy, all patients underwent volume measurement...Nitric oxide crucial to respiration
...s, particularly in disease states characterized by abnormal functioning of endothelial cells lining blood vessels. "We will be trying to correlate the pathophysiology of these disorders with the activity of the red blood cells to get a better idea of how nitric oxide participates in these diseases," ...Other highlights in the June 5 issue of JNCI
...uring DNA replication or repairwas associated with abnormal cytology in the breast and a woman's overall risk ...en with normal cytology and in 14 of 19 women with abnormal cytology. The mean lifetime risk for developing breast cancer, calculated using the Gail model, was ...Protein essential for switching on T-cell response
...T-cell production. However, by four weeks of age, abnormal T-cells had rapidly expanded and the mice showed signs of autoimmune disease. The researchers discovered that the LAT protein produced by the mutated mice, while retaining the ability to connect T-cell activating receptors to the Ras signaling pathwa...Women with ovary disease may also have high risk for heart disease
...ich is marked by one or more symptoms that include abnormal menstruation, excessive body hair, obesity, and infertility. In the first study of its kind, researchers compared the elasticity of arteries in women with normal ovaries, those with PCO, and those with PCOS. On average, women with PCOS had arteries ...More clues about obesity revealed by brain-imaging study
...ith many contributing factors, including genetics, abnormal eating behavior, lack of exercise, and cultural influences, as well as cerebral mechanisms, which are not yet fully understood. In a recent study, he and his team found that obese people have fewer brain receptors for dopamine, a neurotransmitter tha...Detection of glucose intolerance after heart attack could identify risk of cardiovascular disease
...ations at discharge were independent predictors of abnormal glucose tolerance. In an accompanying Commentary (p 2127), Stephen Haffner from the University of Texas, USA, states: "in view of the high risk of future coronary heart disease in patients with diabetes, it is reasonable to suggest an oral glucose-to...If screening shows osteoporosis, many women may not tell their physician or begin treatment
...l deformity often referred to as "dowager's hump," abnormal curvature of the spine resulting from collapse of the spinal column that produces a rounded hump in the upper back. The best method to determine if a person has osteoporosis is a dual-energy x-ray absorptiometry (DXA) scan, which can assesses the b...Detection of glucose intolerance after heart attack
...ations at discharge were independent predictors of abnormal glucose tolerance. In an accompanying Commentary, Stephen Haffner from the University of Texas, USA, states: "in view of the high risk of future coronary heart disease in patients with diabetes, it is reasonable to suggest an oral glucose-tolerance t...Think youre healthy? Open wide and look inside
...s, bleeding upon brushing or flossing or any other abnormal symptoms in your mouth, you should call your dentist or periodontist for a complete examination sooner rather than later," said Bueltmann. A referral to a periodontist and free oral health brochures are available by calling 800-FLOSS-EM or visiting t...Cervical tissue changes may explain false negative pap smears
...er early- because aberrant tissue changes can keep abnormal cells from being picked up during the exam, accord...esults come back negative even when a biopsy shows abnormal lesions, and researchers have not been able to conclusively explain the inconsistencies. A substance...Simple reminder can help patients avoid dangerous infection
...bloodstream, travels to the heart, and attaches to abnormal heart valves and tissue," he explains. Medical and...g endocarditis is greatly reduced in patients with abnormal heart valves and congenital heart disease. Heart-valve problems are typically diagnosed by a cardiac...New practice guidelines focus on neuroimaging of premature and low birth weight babies
... of all very low birth weight preterm infants with abnormal results from the cranial US testing. When a full term infant with coma or seizures has evidence of birth trauma, CT should be performed to detect any hemmorrhages. If the CT findings do not demonstrate bleeding in the baby's brain, then an MRI shoul...Bleach-producing enzyme found to modulate blood vessel dilation during inflammation
...xidase enzyme due to hereditary deficiency display abnormal vascular responses during inflammation....New gene therapy protocol: First successful treatment for 'bubble babies'
...donor, is the recommended treatment to replace the abnormal bone marrow stem cells and create a normal immune ... because only a minute fraction of the genetically abnormal bone marrow products were repaired, Prof. Slavin said. The patients still required ADA replacement t...Hypertension is study focus of $10 million NIH grant to MCG
...explain why. They've also found evidence about how abnormal responses to stress and sodium occur, how damage to the blood vessels results and how it might be prevented. One project under the NIH grant will continue Dr. Treiber's longitudinal studies of children with a family history of hypertension. But now ...Vaccination delays onset of prion brain disease in mice
...ases are characterized by progressive dementia and abnormal limb movements and affect people as well as animal...ul of other conditions, certain proteins fold into abnormal forms, or conformations, in the brain. These misfolded proteins tend to aggregate in toxic, cell-kil...Lingering cognitive impairment may be linked to coronary bypass surgery
...geries -- exposes patients' brains to a variety of abnormal physiological conditions, including inflammation, lack of oxygen, elevated blood sugar, lowered body temperature, showers of microscopic blood clots, and the presence of a lot of amnesia-causing drugs. The Neuropsychology article is both a reminder ...American Heart Association updates heart attack, stroke prevention guidelines
...oke risk in people who have atrial fibrillation an abnormal heart rhythm that can propel blood clots from the ... prevent clot formation, or treatment to eliminate abnormal heartbeats, substantially reduces the risk of stroke associated with atrial fibrillation. The panel...Aspirin's target, the COX-2 enzyme, linked to cancer of the uterus
...et off a cascade of molecular events, including an abnormal increase in estrogen, that leads to tumor growth. "The findings suggest that everyday drugs like aspirin or ibuprofen -- nonsteroidal anti-inflammatory drugs that block the COX-2 enzyme -- might be tried as treatments for uterine cancer in combinatio...