Statement from Dr. Claude Lenfant, director, NHLBI and Dr. Phillip Gorden, director, NIDDK
...ed. Rates of diabetes and milder forms of glucose abnormalities areincreasing in the U.S. Above age 65 years, almost half of Americans haveabnormal glucose levels. Type 2 diabetes most often occurs in overweight or obese adults after the age of30 and typically is preceded by insulin resistance, which also is rel...UT Southwestern to study lipodystrophy syndrome in HIV-infected patients
...hat we learn how to preventlipodystrophy and lipid abnormalities while also successfully treating HIVdisease." Garg, a senior investigator in the Center for Human Nutrition at UTSouthwestern, has been examining genetic and acquired lipodystrophies for morethan a decade and will serve as principal investigator of t...Camelford water contamination did lead to cerebral function damage
...fected people. They found that there were several abnormalities in people exposed to aluminium and other contaminants in the Camelford incident. For example, they found that their psychomotor performance was poorer than the team would have expected based on the IQ of affected individuals before exposure. Altman......s of schizophrenia, by identifying proteinand gene abnormalities in the brain, and by testing concepts with brain imagingtechniques which allows scientists to picture events in the human brain,"commented Paul Herrling, Global Head of Novartis Pharma Research. Finding better drug treatment for schizophrenia has bee......fer from a dyslipidaemia. This is characterized by abnormalities in the way they metabolise fats, which may lead to high levels of both triglycerides and free fatty acids in the blood, and a high total cholesterol:HDL cholesterol (the 'good' cholesterol) ratio. Dyslipidaemia is strongly linked with insulin resista...NICHD funded researchers discover gene for Rett syndrome
...or hand "washing." They may also develop breathing abnormalities andexperience sudden, unexpected heart attacks. "Rett syndrome has long frustrated researchers and clinicians because ofits unusual pattern of inheritance," said NICHD Director Duane Alexander, M.D. "The discovery of Dr. Zoghbi and her cowork...UF researchers show magnetic stimulation may be a safe alternative to shock therapy
...ft frontal lobe,where some researchers believe the abnormalities associated with depressionoriginate. Patients remain awake during the treatment, and none of those treated in the UFstudy developed significant side effects or memory loss. Triggs said the majortheoretical risk of rTMS is the possibility of inducing...NIAID funds three Chronic Fatigue Syndrome (CFS) Research Centers
...attempting to characterize heart andnervous system abnormalities in subsets of persons with CFS. The University ofWashington center, directed by Dedra Buchwald, M.D., will receive its secondcenters award and will continue its examination of identical and non-identicaltwins, including twin sets in which one twin h...Lack of sleep alters hormones, metabolism
...ulin resistance and memoryimpairment. All of these abnormalities quickly returned to baseline during the recoveryperiod, when subjects spent 12 hours in bed. In fact, as the subjects spentmore than eight hours a night in bed, their laboratory values moved beyond the"normal" or baseline standards, suggesting that ...Mayo Clinic investigates new device to regulate beating of the heart and improve pump function
...cent of people with advanced heart failure develop abnormalities of the heart's electrical impulses, which disturb the timing of the contractions of the heart's two lower chambers, called ventricles, so that they do not contract simultaneously. When this occurs, the symptoms of heart failure, including shortness ...Chromosome changes predict more deadly prostate tumors
... study. They found that men with a specific set of abnormalities (including extra copies of the c-myc gene) on chromosome 8 had a 30 percent survival rate after 10 years, compared to a 78 percent 10-year survival among men with normal chromosomes. The lead author of the study, Robert Jenkins, Ph.D., says that the ...Teasing out the early steps of neurodegeneration
...inocerebellar ataxia type 1 (SCA1) have pinpointed abnormalities in gene expression that occur long before signs of the disease appear. The researchers believe that their discovery could lay the groundwork for tracing the cascade of malfunctions that ultimately leads to the degeneration of specific groups of neuro...Duke geneticists unraveling the tangled web of autism
...an their quest to find genes associated with brain abnormalities by using the same approach they used to find genes... they found that the autistic children had genetic abnormalities in this tiny region of chromosome 15 that contains about 50 genes. "Our studies, and those of other...New cancer classification brings quicker treatment to some
...cs -- the study of chromosomal abnormalities -- in identification of subsets of leukemia. It also takes into account such things as the response of the cells to certain antibodies, the clinical course of the disease, and ...Genetic test for melanoma developed at UCSF
...n a year. The test, which detects chromosomal abnormalities that characterize cancerous skin cells, was descr...noses, LeBoit said. "Now we have a common set of abnormalities for melanoma. And most tumors have two, three or four of them," he said. Before pathology labs...New evidence suggests reconsidering causes and treatments for schizophrenia
... says this reinforces their supposition that sleep abnormalities in schizophrenia - like positive symptoms - are reliant on the balance of cholinergic and other transmitters, primarily those of the dopaminergic system. As cholinergic activity is suppressed, there is an increase in dopaminergic activity and vice ve...Biomedical informatics research group develops teaching/diagnostic software
...to work through a process where they "arrange data abnormalities in a causal hierarchy." For example, clinical pathologists routinely evaluate blood and urinary chemistry assays that provide information on blood hemoglobin, white blood cells and a range of other parameters. By systematically identifying all availa...Government asks UNC to develop school program about alcohol and birth defects
...rstanding of the scientific basis of developmental abnormalities resulting from prenatal alcohol use. "For example, we've developed an experiment involving brine shrimp, commonly referred to as 'sea monkeys,'" Sulik said. "In one day, students can observe how incubating shrimp eggs in alcohol affects their devel......erapy (ICAAC). Fat maldistribution and metabolic abnormalities (FMMA), often is referred to as "lipodystrophy syn...ing of fat from the arms, face or legs. Metabolic abnormalities include abnormally high lipid or glucose levels in the blood and insulin resistance. These metaboli...... of Psychiatry shows for the first time that brain abnormalities and social difficulties in schizophrenia are relat...s the first study when fMRI has linked these brain abnormalities to the social problems seen in schizophrenia. Dr Sharma feels that social cognition is an area that...